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Frondoside A

Catalog No. T11325   CAS 127367-76-4

possesses anticancer, anti-invasive, anti-metastasis, anti-angiogenic and pro-apoptosis properties with high safety.Frondoside A, a natural glycoside extracted from the sea cucumber, Cucumaria frondosa,

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Frondoside A Chemical Structure
Frondoside A, CAS 127367-76-4
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Biological Description
Chemical Properties
Storage & Solubility Information
Description possesses anticancer, anti-invasive, anti-metastasis, anti-angiogenic and pro-apoptosis properties with high safety.Frondoside A, a natural glycoside extracted from the sea cucumber, Cucumaria frondosa,
In vitro Frondoside A (0-5 μM, 24 hours)causes concentration-dependent reduction in viability of lung and breast cancer cells through a caspase 3/7-dependent cell death pathway.
In vivo Frondoside A (0.01 and 1 mg/kg/ day i.p. for 25 days) significantly decreases the growth, the lymph node metastasis?and angiogenesis of LNM35 tumor xenografts in mice, without obvious toxic side-effects.
Molecular Weight 1336.45
Formula C60H96NaO29S
CAS No. 127367-76-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Sajwani FH, et al. Frondoside A is a potential anticancer agent from sea cucumbers. J Cancer Res Ther. 2019 Jul-Sep;15(5):953-960. 2. Attoub S, et al. Frondoside a suppressive effects on lung cancer survival, tumor growth, angiogenesis, invasion, and metastasis. PLoS One. 2013;8(1):e53087.

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Keywords

Frondoside A 127367-76-4 Others inhibitor inhibit

 

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