pigmentation — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4848	Mandelic acid	acidomandelico,DL-Mandelic acid	Others , Endogenous Metabolite , Antibacterial
	It is an isomer of cresotinic acid (2-hydroxy-3-methylbenzoic acid) and oxymethylbenzoic acid (2-methoxybenzoic acid). Derivatives of mandelic acid are formed as a result of metabolism of adrenaline and noradrenaline by ...		Others , Endogenous Metabolite , Antibacterial
T7769	Nonapeptide-1	Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-,Melanostatine™ 5	Others
	Nonapeptide-1 (Melanostatine™ 5) can inhibit the synthesis of melanin, which makes it of interest for treating certain skin conditions.		Others
TN2296	Vinaginsenoside R4		Others
	Vinaginsenoside R4 was isolated from the leaves of hydroponically grown ginseng. It inhibits melanin biosynthesis and enhances pigmentation in zebrafish without any cytotoxic effects on melan-a cells. It may have potenti...		Others
TP2487	Oligopeptide-68 Acetate	Oligopeptide-68 Acetate(1206525-47-4 Free base)	Others
	Oligopeptide-68 Acetate is a peptide. It is a novel whitening ingredient that mimics the binding of TGF-β to cell surface receptors to reduce induced and hereditary pigmentation by inhibiting MITF intramolecular channels...		Others
T0926	Azelaic acid	Finacea,Azelex,Nonanedioic acid,Anchoic acid	Others , DNA/RNA Synthesis , Endogenous Metabolite
	Azelaic acid (Anchoic acid) is a component of hair and skin conditioners and is produced by the ozonolysis of oleic acid. Azelaic acid has bacteriostatic activity against Propionibacterium acnes and Staphylococcus epider...		Others , DNA/RNA Synthesis , Endogenous Metabolite
T3606	γ-Oryzanol	Gamma-Oryzanol,Oliver,Gammariza	DNA Methyltransferase
	γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the destruction of free radicals in the skin. It has recently b...		DNA Methyltransferase
T25310	Dersimelagon	MT-7117	Melanocortin Receptor
	Dersimelagon (MT-7117) is an orally active, selective agonist for the melanocortin 1 receptor (MC1R), demonstrating EC50 values of 8.16 nM (h), 3.91 nM (cm), 1.14 nM (m), and 0.251 nM (r) across species such as human, cy...		Melanocortin Receptor
T19923	(+)-Pinanediol	2,3-cs/ex-PinD,2,3-cis/exo-pinanediol
	(+)-Pinanediol is an effective inducer of melanogenesis. In S91 cells, it acts by inducing higher levels of pigmentation and synthesis of nitric oxide (NO).
TN3882	Dodoviscin A		cAMP , Tyrosinase , transporter
	Dodoviscin A may be a new promising pigmentation-altering agent for cosmetic and therapeutic applications, it can inhibit melanin biosynthesis induced by 3-isobutyl-1-methylxanthine and PD98059.Dodoviscin A can promote a...		cAMP , Tyrosinase , transporter
T83492	[His7] Corazonin
	[His7] Corazonin, a neurohormone in Locusta migratoria, stimulates dark pigmentation in the insect's cuticle and epidermis [1].
T79996	N,N′-Diferuloylputrescine		Melanocortin Receptor
	N,N′-Diferuloylputrescine acts as a pigment inhibitor, showing a 57% reduction in pigmentation. It also considerably diminishes the protein expression of MITF and displays potent antioxidant properties as a radical scave...		Melanocortin Receptor
T75715	Nonapeptide-1 acetate salt
	Nonapeptide-1 (Melanostatine-5) acetate salt, a peptide hormone, functions as a selective and competitive antagonist of the melanocortin 1 receptor (MC1R) with a binding affinity (K i) of 40 nM. It effectively inhibits α...
T83924	(R)-(+)-Deoxyarbutin
	(R)-(+)-Deoxyarbutin, an isomer of deoxyarbutin, acts as a tyrosinase inhibitor. Effective at a concentration of 21 µM, it diminishes tyrosinase activity and has been demonstrated to lighten the skin in hairless guinea p...
TP2212	A-MSH, amide		Others
	a-MSH, amide is a peptide with the sequence Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2, MW= 1664.9. The melanocyte-stimulating hormones (collectively referred to as MSH or intermedins) are a class of pept...		Others