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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16348 | NS5806 | NS-5806 | Potassium Channel |
NS5806 is an effective potassium current activator. NS5806 slows KV4.3 and KV4.2 current decay in channel complexes containing KChIP2. NS5806 enhances KV4.3/KChIP2 peak current amplitudes (EC50: 5.3 μM). | |||
T9796 | 22393-62-0_peak 2 | ||
22393-62-0_peak 2 exhibits some aspects of the antiestrogenic activity and other actions that may be connected to the estrogenic properties. A mixture of the (Z)- and (E)-isomers (Broparestrol, INN) is used in dermatol... | |||
TN2347 | Methylsticin | Methysticin | Others |
Methysticin is a kavalactone isolated from the kava roots. Methylsticin (Methysticin) exhibit osteoclast formation inhibitory activity. It inhibits activation of NF-χB in lung adenocarcinoma tissue, activates Nrf2 in neu... | |||
T33492 | Methyl pyropheophorbide-a | MPPa (Methyl pyropheophorbide-a),NSC267052,Pyropheophorbidea,MPPa,NSC-267052,NSC 267052 | |
Pyropheophorbide-a methyl ester (MPPa) is a PDT photosensitizer, and is also a semisynthetic natural product derived from chlorophyll a. The absorption peak of MPPa in organic solvent and in cells was at 667 and 674 nm, ... | |||
T9009 | ICA-105574 | ICA,3-nitro-N-[4-phenoxyphenyl]-benzamide | HER |
ICA-105574 (ICA) is an activator of hERG that binds to the channel to remove inactivation, thus increasing peak current amplitude and shortening the action potential. It also modulates activation kinetics of the channel. | |||
T8617 | GMQ hydrochloride | NSC 403387 hydrochloride | Others |
GMQ hydrochloride (NSC-403387 hydrochloride) is a potent and selective acid-sensing ion channel (ASIC) modulator. It activates ASIC3 channels under neutral pH and blocks acid-induced maximal peak current. | |||
TN1918 | Medicarpin | Apoptosis , BCL , ROS , JNK | |
Medicarpin, a legume phytoalexin, acts as an estrogen receptor (ER) agonist, can stimulate osteoblast differentiation likely via ERα², promote achievement of peak bone mass, and is devoid of uterine estrogenicity; in add... | |||
T3644 | U93631 | GABA Receptor | |
GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction. Accelerates the decay of GABA-induced Cl- currents with little effect on peak amplitude... | |||
T26862 | BMS-902483 | ||
BMS-902483 is a potent α7 partial agonist. BMS-902483 improved cognition in preclinical rodent models. BMS-902483 showed FLIR α7 EC50=9.3nM; α7 Electrophysiology, rat; Area EC50 = 140 nM; Peak, Area (Ymax %) = 40, 54. 5-... | |||
T28491 | R-1663 | R1663 | |
R-1663 is a factor Xa inhibitor. R-1663 prolonged clotting times, inhibited thrombin generation (peak height and endogenous thrombin potential [ETP]) and anti-factor Xa activity in a concentration-dependent manner withou... | |||
T19304 | EC-17 disodium salt | Others | |
EC-17 (disodium salt), a folate receptor alpha (FRα) targeting contrast agent, exhibits fluorescent properties within the visible light spectrum, characterized by peak excitation and emission wavelengths of 470/520 nm, r... | |||
T70773 | Noberastine citrate | ||
Noberastine citrate, a histamine H1 antagonist, has potent and specific peripheral antihistaminic activity. Noberastine, a furan derivative of nor-astemizole (an astemizole metabolite), has been shown to have a more rapi... | |||
TN6514 | 2-Carboxybenzaldehyde | ||
The major peak of 2-Carboxybenzaldehyde reductase activity in human liver co-purifies with hAFAR protein. Sulphydryl substances and some proteins play important roles in preserving the molecular and catalytic properties ... | |||
T83352 | 3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin | ||
3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin serves as a pteridine-based fluorescent guanosine analogue and DNA uptake tracer utilized extensively for investigation into DNA binding and dynamics. It exhibits an... | |||
T32426 | KT 1 | KT-1,KT1 | |
KT 1 decreased aortic pressure, renal blood flow, left ventricular enddiastolic pressure and resistances of total peripheral, vertebral, coronary and renal vasculatures and increased aortic blood flow, vertebral blood fl... | |||
T39254 | ICG-carboxylic acid | ||
ICG-carboxylic acid is a fluorescent probe in the near-infrared (NIR) range. It is derived from indocyanine green (ICG), a commonly used fluorescent dye in medical diagnostics. ICG exhibits a peak absorption at 800 nm, a... | |||
T71425 | Noberastine maleate | ||
Noberastine maleate, a histamine H1 antagonist, has potent and specific peripheral antihistaminic activity. Noberastine, a furan derivative of nor-astemizole (an astemizole metabolite), has been shown to have a more rapi... | |||
T37764 | Cal Green™ 1 (potassium salt) | ||
Cal Green 1 is a cell-impermeant fluorescent calcium indicator that is characterized by high quantum yield and low phototoxicity. Its peak excitation and emission wavelengths (506 and 531 nm, respectively) are comparabl... | |||
T82726 | Chromotrope 2R | ||
Chromotrope 2R functions as a chromogenic analytical probe for protein quantification, staining basic proteins red and exhibiting a peak wavelength shift from 501.6 nm to 567 nm [1]. | |||
T62376 | GNE-9278 | ||
GNE-9278 is a highly selective NMDAR orthosteric modulator that acts on the GluN1 transmembrane structural domain (TMD).GNE-9278 acts on activated NMDAR and increases peak current and agonist affinity. |