nut — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TJS0123	Guvacine ethyl ester	PT00442-2	Others
	Guvacine ethyl ester (Arecoline) is an alkaloid found in betel nut that is used in the synthesis of GABA uptake inhibitors.		Others
T6023	Nutlin-3a	(-)-Nutlin-3,Nutlin-3a chiral,(−)-Nutlin-3	Apoptosis , E1/E2/E3 Enzyme , Autophagy
	Nutlin-3a ((−)-Nutlin-3), the active enantiomer of Nutlin-3, inhibits MDM2-p53 interactions and stabilizes the p53 protein.		Apoptosis , E1/E2/E3 Enzyme , Autophagy
T6614	Nutlin-3b	(+)-Nutlin-3	Mdm2 , E1/E2/E3 Enzyme
	Nutlin-3b ((+)-Nutlin-3) is a p53/MDM2 antagonist or inhibitor (IC50: 13.6 μM), 150-fold less potent (+)-enantiomer of Nutlin-3 as in comparison with opposite (-)-enantiomer Nutlin-3a.		Mdm2 , E1/E2/E3 Enzyme
T9924	Obinutuzumab	Obinutuzumab/afutuzumab	Others
	Obinutuzumab (Obinutuzumab/afutuzumab) GA101) is a glycoengineered Type II CD20 monoclonal antibody in development for non-Hodgkin lymphoma.		Others
T2158	Nutlin-3	Nutlin3	E1/E2/E3 Enzyme
	Nutlin-3 is an MDM2 antagonist.Nutlin-3 inhibits the MDM2-p53 interaction (IC50: 0.09 μM) and activates p53. Antiproliferative agent; chemotherapeutic agent; induces apoptosis in Y cells.		E1/E2/E3 Enzyme
T6254	Idasanutlin	RG7388,Ro 5503781	Mdm2 , E1/E2/E3 Enzyme
	Idasanutlin (Ro 5503781) (RG-7388) is an effective and specific p53-MDM2 inhibitor (IC50: 6 nM).		Mdm2 , E1/E2/E3 Enzyme
T80878	Vanutide cridificar	PF 05236806,ACC-001
	Vanutide cridificar (ACC-001) is an aminoterminal Aβ1-7 peptide conjugate, employed in Alzheimer’s disease (AD) research [1].
T124114	Microminutin
	Microminutin is a useful organic compound for research related to life sciences. The catalog number is T124114 and the CAS number is 84041-46-3.
T17902	Nutlin-C1-amido-PEG4-C2-N3	E3 ligase Ligand-Linker Conjugates 48,MDM2 Ligand-Linker Conjugates 1	Others
	Nutlin-C1-amido-PEG4-C2-N3 is a novel compound that functions as a ligand-linker conjugate for the E3 ligase. It is a synthesized molecule incorporating the MDM2 ligand derived from Nutlin 3, and a 4-unit PEG linker. Thi...		Others
T36358	Diminutol
	Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization ...
T69115	Nutlin-1
	Nutlin-1 is a p53-MDM2 binding inhibitor, p-Glycoprotein (p-gp) transport substrate, and antitumor agent.
T126508	Cornutaside C
	Cornutaside C is a useful organic compound for research related to life sciences. The catalog number is T126508 and the CAS number is 102848-64-6.
T17873	(4R,5S)-nutlin carboxylic acid	E3 ligase Ligand 15,MDM2 ligand 2	Others
	(4R,5S)-Nutlin Carboxylic Acid (MDM2 Ligand 2), a Nutlin 3-based MDM2 ligand, can be conjugated to a protein-binding ligand via a linker to create PROTACs[1].		Others
T17874	Nutlin carboxylic acid	MDM2 ligand 1,E3 ligase Ligand 16	Others
	Nutlin Carboxylic Acid (MDM2 ligand 1), derived from Nutlin 3, serves as an MDM2 ligand. It can be attached to a protein ligand via a linker to create PROTACs[1].		Others
T75589	Bitis Cornuta Venom
	Bitis Cornuta (Many-horned Adder) Venom, sourced from Bitis Cornuta, comprises snake venom phospholipase A2 (sPLA2) toxins that exhibit anticoagulant properties by inhibiting the prothrombinase complex, consequently prom...
T69114	Nutlin-2
	Nutlin-2 is a potent and selective p53-MDM2 binding inhibitor.
TN3594	Cardanol (C15:1)		Apoptosis , Others
	Cardanol (C15:1), found in cashew nut shell liquid, induces mitochondria-associated apoptosis in human melanoma cells.		Apoptosis , Others
T68953	Arecoline		Reactive Oxygen Species , AChR
	Arecoline is a natural alkaloid derived from areca nut in the palm family and is a potent nicotine and partial agonist of muscarinic acetylcholine receptors. Arecoline has anti-anxiety and anti-parasitic activity, can in...		Reactive Oxygen Species , AChR
T71813	Cardanol diene
	Cardanol diene is a phenol found in cashew nut shell liquid that inhibits tyrosinase with an IC50 value of 52.5 μM in vitro. Cardanol diene is also used to synthesize cardanol-metal complexes that inhibit uropathogenic E...
T37555	Cardanol triene
	Cardanol triene is a phenol found in cashew nut shell liquid that reversibly inhibits tyrosinase with an IC50 value of 40.5 μM in vitro. A mixture of cardanol mono-, di-, and triene is used to synthesize cardanol-metal c...