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Search Results for " non-classical "

7

Compounds

Cat No. Product Name Synonyms Targets
T37709 2,2,2-Trichloroethanol Potassium Channel , Endogenous Metabolite
2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4)[1]. 2,2,2-trichloroethanol activates a nonclassical ...
T35394 Sintilimab (anti-PD-1) IBI308,Sintilimab (anti-PD-1) PD-1/PD-L1
Sintilimab (IBI308) is a humanized IgG4 monoclonal antibody with significant anti-tumor activity that restores endogenous anti-tumor T-cell responses by binding to PD-1 and thereby blocking the interaction of PD-1 with i...
T68070 Fezolamine Norepinephrine
Fezolamine is a novel orally available non-tricyclic compound with antidepressant activity. It is three to two times more selective in blocking synaptosomal uptake of [3H]norepinephrine than uptake of [4H]3-hydroxytrypta...
TP1565L1 Foxy-5 Ammonium Salt Foxy-5 Ammonium Salt(881188-51-8 Free base) Wnt/beta-catenin
Foxy-5 Ammonium Salt is a WNT5A agonist, a mimetic peptide of WNT5A, a non-classical member of the Wnt family.Foxy-5 Ammonium Salt triggers cytoplasmic free calcium signaling without affecting β-catenin activation and in...
T26611 AM7499 AM 7499,AM-7499
AM7499 is a non-selective cannabinoid receptor agonist with remarkably high in vitro and in vivo potency. It is readily hydrolysed by plasma esterases and to be less prone to deposition in bodily fat than existing classi...
T76709 Zimberelimab
Zimberelimab, a fully human IgG4 monoclonal antibody targeting PD-1 with high affinity and selectivity, exhibits antitumor activities. It is applicable in research on various cancers, including cervical cancer, non-small...
T81423 Polzastobart JTX 8064
Polzastobart (JTX-8064), a humanized IgG4 monoclonal antibody, functions as an antagonist selectively targeting LILRB2. It inhibits its interaction with both classical and non-classical MHC I molecules. By preventing LIL...
TargetMol