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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T37709 | 2,2,2-Trichloroethanol | Potassium Channel , Endogenous Metabolite | |
2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4)[1]. 2,2,2-trichloroethanol activates a nonclassical ... | |||
T35394 | Sintilimab (anti-PD-1) | IBI308,Sintilimab (anti-PD-1) | PD-1/PD-L1 |
Sintilimab (IBI308) is a humanized IgG4 monoclonal antibody with significant anti-tumor activity that restores endogenous anti-tumor T-cell responses by binding to PD-1 and thereby blocking the interaction of PD-1 with i... | |||
T68070 | Fezolamine | Norepinephrine | |
Fezolamine is a novel orally available non-tricyclic compound with antidepressant activity. It is three to two times more selective in blocking synaptosomal uptake of [3H]norepinephrine than uptake of [4H]3-hydroxytrypta... | |||
TP1565L1 | Foxy-5 Ammonium Salt | Foxy-5 Ammonium Salt(881188-51-8 Free base) | Wnt/beta-catenin |
Foxy-5 Ammonium Salt is a WNT5A agonist, a mimetic peptide of WNT5A, a non-classical member of the Wnt family.Foxy-5 Ammonium Salt triggers cytoplasmic free calcium signaling without affecting β-catenin activation and in... | |||
T26611 | AM7499 | AM 7499,AM-7499 | |
AM7499 is a non-selective cannabinoid receptor agonist with remarkably high in vitro and in vivo potency. It is readily hydrolysed by plasma esterases and to be less prone to deposition in bodily fat than existing classi... | |||
T76709 | Zimberelimab | ||
Zimberelimab, a fully human IgG4 monoclonal antibody targeting PD-1 with high affinity and selectivity, exhibits antitumor activities. It is applicable in research on various cancers, including cervical cancer, non-small... | |||
T81423 | Polzastobart | JTX 8064 | |
Polzastobart (JTX-8064), a humanized IgG4 monoclonal antibody, functions as an antagonist selectively targeting LILRB2. It inhibits its interaction with both classical and non-classical MHC I molecules. By preventing LIL... |