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Cat No. | Product Name | Synonyms | Targets |
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T1643 | Penciclovir | BRL 39123,VSA 671 | HCV Protease , Antifection , HSV |
Penciclovir (BRL 39123) is a Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor. In HSV infected cells, penciclovir is phosphorylated by viral thymidine kinase and subsequently converted by cellular kinases into the ... | |||
T8669 | 3,3',4,4'-Benzophenonetetracarboxylic dianhydride | Others | |
3,3',4,4'-Benzophenonetetracarboxylic dianhydride is a compound used as a polyimide precursor in the production of polyimide films and adhesives. It is a non-toxic material with no known adverse effects on human health. | |||
T67791 | BMS-903452 | GPR | |
BMS-903452 is a potent and selective GPR119 agonist with EC50 of 14 nM. BMS-903452 is indicated for the treatment of acute and chronic rodent diabetes. GPR119 was mainly expressed in pancreatic b cells and gastrointestin... | |||
T12009 | Telomerase-IN-1 | Telomerase | |
Telomerase-IN-1 is a telomerase inhibitor (IC50: 0.19 μM). telomerase-IN-1 activates hTERT expression through the endoplasmic reticulum stress (ERS) of the ER overreaction (EOR), which then induces ERS, leading to apopto... | |||
T3779 | Crocin II | Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B | Caspase , COX , NO Synthase |
Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expres... | |||
T4776 | Glycerol | Glycerin | Endogenous Metabolite |
Glycerol or glycerin is a colourless, odourless, viscous liquid that is sweet-tasting and mostly non-toxic. It is widely used in the food industry as a sweetener and humectant and in pharmaceutical formulations. Glycerol... | |||
T28815 | SM21 perchlorate | SM21,SM 21,SM-21 | |
SM21 is a highly potent antifungal agent (MIC = 0.2-1.6 µg/ml) with no toxic to various human cell lines or bacterial species in vitro and was active against Candida isolates that are resistant to existing antifungal age... | |||
TN4801 | Piscidinol A | Others | |
Piscidinol A is toxic against the 4T1 and HEp2 cancer cell lines, the IC50 of 8.0 ± 0.03 and 8.4 ± 0.01 uM, respectively. It can inhibit NO production in mouse peritoneal macrophages with inhibitory ratios ranging from 3... | |||
T78693 | Anticancer agent 108 | ||
Anticancer Agent 108 (Compound 3.10) serves as a potent P-gp inhibitor exhibiting considerable antitumor properties while maintaining reduced toxicity to both normal and pseudonormal cells; it also demonstrated no acute ... | |||
T38152 | Gilvocarcin M | ||
Gilvocarcin M is an antibiotic originally isolated from S. gilvotanareus. It is active against S. aureus when used at a concentration of 32 μg/ml. Gilvocarcin M inhibits growth of KB cells (IC50 = 0.52 μg/ml) but has no ... | |||
T68502 | Dibrospidium Free Base | ||
Dibrospidium Free Base is a dispirotripiperazine derivative and alkylating agent with potential antineoplastic and anti-inflammatory activities. The duration of DNA synthesis inhibition in tumor cells was found to correl... | |||
T66029 | 3,4-Dehydro-L-proline | ||
The leguminous shrub,Leucaena leucocephala(Leucaena) is wide‐spread in tropical and subtropical agricultural systems and provides a ready source of protein for livestock. However, the presence of mimosine, a non‐protein,... | |||
T35904 | O-11 | ||
O-11 is an analog of the fully saturated, 14-carbon fatty acid myristic acid, in which the methylene group at position 11 is replaced with oxygen. It is highly effective and selective at killingTrypanosoma brucei, the pr... |