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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T75422 | Monoamine oxidase | ||
Monoamine oxidase, an enzyme comprising various polypeptides, catalyzes the oxidative deamination of diverse biological amines within both brain and peripheral tissues, yielding hydrogen peroxide in the process. This enz... | |||
T60806 | Monoamine Oxidase B inhibitor 2 | ||
Monoamine Oxidase B inhibitor 2 is a potent, reversible, orally active and selective inhibitor of monoamine oxidase B (MAO-B) (IC50 = 1.33 nM) which can across the blood-brain barrier (BBB). Monoamine Oxidase B inhibitor... | |||
T61463 | Monoamine oxidase/Aromatase-IN-1 | ||
Monoamine oxidase/Aromatase-IN-1 (compound 2q) is a potent dual inhibitor of monoamine oxidase (MAO) and aromatase, with IC50 values of 39 nM and 31 nM for MAO-B and aromatase, respectively. It holds significant potentia... | |||
T60656 | Monoamine Oxidase B inhibitor 1 | ||
Monoamine Oxidase B inhibitor 1 is a potent, reversible, orally active and selective monoamine oxidase B (MAO-B) inhibitor (IC50 = 0.02 nM) that can across the blood-brain barrier (BBB). Monoamine Oxidase B inhibitor 1 s... | |||
T4559 | Isocarboxazid | Monoamine Oxidase | |
Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor.[2] It is used in the treatment of major depression, dysthymic disorder, atypical disor... | |||
T22605 | Bifemelane hydrochloride | MAO , Monoamine Oxidase | |
Bifemelane hydrochloride is a MAO inhibitor | |||
T8849 | PF-9601N | MAO | |
PF-9601N showed high potency and selectivity as a MAO-BI (monoamine oxidase type B inhibitor) and also demonstrated remarkable neuroprotective properties in several in vivo and cellular models of PD. | |||
T7147 | Valbenazine | NBI-98854 | Monoamine Transporter |
Valbenazine (NBI-98854), a highly selective vesicular monoamine transporter 2(VMAT2) inhibitor, is approved for the treatment of tardive dyskinesia. | |||
T0235 | Modaline sulfate | MAO , Monoamine Oxidase | |
Modaline was a 2-methyl-3-piperidinopyrazine derivative found to inhibit monoamine oxidase (MAO) and showed a curative effect for the anti-depressant. Similar to other MAO inhibitors, it enhanced convulsions induced by t... | |||
T12585 | PXS-5153A | Others , Monoamine Oxidase | |
PXS-5153A is an effective, selective, and fast-acting inhibitor of lysyl oxidase like 2/3 enzymes with enzymatic activity almost entirely blocked within 15 minutes. PXS-5153A could reduce crosslinks and ameliorates fibro... | |||
T0084 | Moclobemide | Ro111163 | MAO , Monoamine Oxidase |
Moclobemide (Ro111163) is a reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties. | |||
T2900 | Paeonol | Peonol | MAO , Autophagy , Monoamine Oxidase |
Paeonol (Peonol) is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively. | |||
T6073 | OG-L002 | Histone Demethylase , Monoamine Oxidase , HSV | |
OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively. | |||
TN1120 | Osthenol | MAO , Monoamine Oxidase | |
Osthenol is a natural product, and is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM).It shows antitumor-promoting activity, it also has antifungal and antibacterial activ... | |||
T12584 | PXS-5120A | Others , Monoamine Oxidase | |
PXS-5120A is an irreversible fluoroallylamine Lysyl Oxidase-like 2/3 (LOXL2/3) inhibitor with anti-fibrotic activity. | |||
T1993 | J-147 | J147 | Epigenetic Reader Domain , Dopamine Receptor , Monoamine Oxidase |
J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate... | |||
T3152 | Harmol | Methylpyridoindolol | Others |
Harmol (Methylpyridoindolol) is a β-carboline isolated from nature. | |||
T3596 | TB5 | MAO , Monoamine Oxidase | |
TB5 is a potent, selective and reversible inhibitor of hMAO-B. | |||
T7626 | Budipine | Others | |
Budipine is a low affinity, N-methyl-D-aspartate receptor antagonist,is an antiparkinsonian agent. | |||
T16803 | RS 8359 | MAO | |
RS 8359 is a reversible inhibitor of monoamine oxidase A (MAO-A) with a selectivity ratio of about 2200 for the A:B enzyme types. RS 8359 has antidepressant activity. |