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Search Results for " monoamine "

20

Compounds

Cat No. Product Name Synonyms Targets
T75422 Monoamine oxidase
Monoamine oxidase, an enzyme comprising various polypeptides, catalyzes the oxidative deamination of diverse biological amines within both brain and peripheral tissues, yielding hydrogen peroxide in the process. This enz...
T60806 Monoamine Oxidase B inhibitor 2
Monoamine Oxidase B inhibitor 2 is a potent, reversible, orally active and selective inhibitor of monoamine oxidase B (MAO-B) (IC50 = 1.33 nM) which can across the blood-brain barrier (BBB). Monoamine Oxidase B inhibitor...
T61463 Monoamine oxidase/Aromatase-IN-1
Monoamine oxidase/Aromatase-IN-1 (compound 2q) is a potent dual inhibitor of monoamine oxidase (MAO) and aromatase, with IC50 values of 39 nM and 31 nM for MAO-B and aromatase, respectively. It holds significant potentia...
T60656 Monoamine Oxidase B inhibitor 1
Monoamine Oxidase B inhibitor 1 is a potent, reversible, orally active and selective monoamine oxidase B (MAO-B) inhibitor (IC50 = 0.02 nM) that can across the blood-brain barrier (BBB). Monoamine Oxidase B inhibitor 1 s...
T4559 Isocarboxazid Monoamine Oxidase
Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor.[2] It is used in the treatment of major depression, dysthymic disorder, atypical disor...
T22605 Bifemelane hydrochloride MAO , Monoamine Oxidase
Bifemelane hydrochloride is a MAO inhibitor
T8849 PF-9601N MAO
PF-9601N showed high potency and selectivity as a MAO-BI (monoamine oxidase type B inhibitor) and also demonstrated remarkable neuroprotective properties in several in vivo and cellular models of PD.
T7147 Valbenazine NBI-98854 Monoamine Transporter
Valbenazine (NBI-98854), a highly selective vesicular monoamine transporter 2(VMAT2) inhibitor, is approved for the treatment of tardive dyskinesia.
T0235 Modaline sulfate MAO , Monoamine Oxidase
Modaline was a 2-methyl-3-piperidinopyrazine derivative found to inhibit monoamine oxidase (MAO) and showed a curative effect for the anti-depressant. Similar to other MAO inhibitors, it enhanced convulsions induced by t...
T12585 PXS-5153A Others , Monoamine Oxidase
PXS-5153A is an effective, selective, and fast-acting inhibitor of lysyl oxidase like 2/3 enzymes with enzymatic activity almost entirely blocked within 15 minutes. PXS-5153A could reduce crosslinks and ameliorates fibro...
T0084 Moclobemide Ro111163 MAO , Monoamine Oxidase
Moclobemide (Ro111163) is a reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
T2900 Paeonol Peonol MAO , Autophagy , Monoamine Oxidase
Paeonol (Peonol) is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively.
T6073 OG-L002 Histone Demethylase , Monoamine Oxidase , HSV
OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.
TN1120 Osthenol MAO , Monoamine Oxidase
Osthenol is a natural product, and is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM).It shows antitumor-promoting activity, it also has antifungal and antibacterial activ...
T12584 PXS-5120A Others , Monoamine Oxidase
PXS-5120A is an irreversible fluoroallylamine Lysyl Oxidase-like 2/3 (LOXL2/3) inhibitor with anti-fibrotic activity.
T1993 J-147 J147 Epigenetic Reader Domain , Dopamine Receptor , Monoamine Oxidase
J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate...
T3152 Harmol Methylpyridoindolol Others
Harmol (Methylpyridoindolol) is a β-carboline isolated from nature.
T3596 TB5 MAO , Monoamine Oxidase
TB5 is a potent, selective and reversible inhibitor of hMAO-B.
T7626 Budipine Others
Budipine is a low affinity, N-methyl-D-aspartate receptor antagonist,is an antiparkinsonian agent.
T16803 RS 8359 MAO
RS 8359 is a reversible inhibitor of monoamine oxidase A (MAO-A) with a selectivity ratio of about 2200 for the A:B enzyme types. RS 8359 has antidepressant activity.
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