longevity — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7909	α-Terpinene		Others , Parasite , Antifungal
	α-Terpinene is a terpenoid,has acaricidal, antiprotozoal, and antioxidant properties		Others , Parasite , Antifungal
T2745	18α-Glycyrrhetinic acid	Enoxolone,Glycyrrhetinic acid	Apoptosis , NF-κB , Proteasome
	18α-Glycyrrhetinic acid (Enoxolone) is an inhibitor of NF-kB and an activator of the proteasome, and functions as a longevity-promoting and anti-aggregation factor in multicellular organisms. It induces apoptosis.		Apoptosis , NF-κB , Proteasome
T9257	1,3-BUTANEDIOL		Others , Endogenous Metabolite
	1,3-Butanediol (BD) is a ketogenic substance. Ketone bodies are essential energy substrates in the absence of exogenous nutrients, and more recently, they have been suggested to prevent disease and improve longevity.		Others , Endogenous Metabolite
TP2312	MOTS-c(Human) Acetate（1627580-64-6 free）		Others , AMPK
	MOTS-c(Human) Acetate is a mitochondrial-derived peptide. MOTS-c(human) acetate induces the accumulation of AMP analog AICAR, increases activation of AMPK and expression of its downstream GLUT4. MOTS-c(human) acetate ind...		Others , AMPK
TN4410	Lappaol C		P-gp , JNK
	Lappaol C has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol C also has potential chemosensitizing activity, it may be candidat...		P-gp , JNK
TN1072	Lappaol A		P-gp , JNK
	Lappaol A has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol A also has potential chemosensitizing activity, it may be candidat...		P-gp , JNK
T28898	T145	T 145,T-145
	T145 inhibits growth of Enterococcus faecalis, Staphylococcus aureus and Mycobacterium tuberculosis (Mtb) with sub μg/ml potencies that are potentially therapeutically valuable. T145 minimizes selection of spontaneous re...
TN5044	Specioside		Others
	Specioside has antioxidant, analgesic, anti-dyspeptic, astringent, liver stimulating and wound healing activities. It ameliorates oxidative stress and promotes longevity in Caenorhabditis elegans.		Others
TN4411	Lappaol F		CDK , P-gp , JNK
	1. Lappaol F has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. 2. Lappaol F has potential chemosensitizing activity, it may be c...		CDK , P-gp , JNK
T18061	KB02-SLF		Others
	KB02-SLF is a PROTAC-based nuclear FKBP12 degrader, known as a molecular glue. It facilitates the degradation of nuclear FKBP12 by covalently modifying DCAF16, an E3 ligase. Moreover, KB02-SLF enhances the longevity of p...		Others
T76039	MOTS-c(human) acetate
	MOTS-c(human) acetate, a mitochondrial-derived peptide, induces the accumulation of AMP analog AICAR, enhances AMPK activation, and upregulates its downstream target, GLUT4. This compound promotes glucose uptake and enha...
T74139	MPEG-2000-DSPE
	MPEG-2000-DSPE is a phospholipid PEG conjugate, has both hydrophilicity and hydrophobility. MPEG-2000-DSPE is used in the synthesis of liposomes, increases the hydrophilicity on the surface of liposomes, consequently inc...
T74672	Sirtuin modulator 5
	Sirtuin Modulator 5, a sirtuin modulating agent, activates SIRT1 with an efficacy marked by a DC50 value of less than 50 μM. It is applicable in enhancing cell longevity and is researched for its therapeutic potential in...