interleukin-8 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T83712	Interleukin-8 (54-72) (human) TFA	IL-8 (54-72),C-X-C Motif Chemokine Ligand (54-72),CXCL8 (54-72)
	Interleukin-8 (IL-8) (54-72), a peptide comprising amino acids 54-72 from the mature IL-8 sequence and 81-99 from the pre-processed form, inhibits the flow-based adhesion of primary human neutrophils to human umbilical v...
T6761	Ossirene	AS101	IL Receptor , Caspase , Interleukin
	Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.		IL Receptor , Caspase , Interleukin
T11179	Elubrixin	SB-656933	IL Receptor , CXCR
	Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammat...		IL Receptor , CXCR
T21389	Enprofylline	Enprofilina,3-propylxanthine,3-n-Propylxanthine,Enprofyllinum	Others
	Enprofylline (Enprofilina), a bronchodilator, acts primarily as a competitive nonselective phosphodiesterase inhibitor. Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of sick...		Others
T27695	JTE-607	JTE-607 dihydrochloride,JTE-607 HCl	Cysteine Protease
	JTE-607 is a cytokine production inhibitor. JTE-607 induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.		Cysteine Protease
T9537	N'-Nitro-D-arginine	N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid	Others
	N'-Nitro-D-arginine (N'-Nitro-D-arginine) is a Building Block.		Others
T1955	SB225002		CXCR
	SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.		CXCR
T5680	Aloin(mixture of A&B)		MMP , IL Receptor , Antibacterial , Antifungal
	ALOIN Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells.		MMP , IL Receptor , Antibacterial , Antifungal
T68455	AP23846	AP-23846	Src
	AP23846 is a novel and potent Src family kinase inhibitor that reduces vascular endothelial growth factor and interleukin-8 expression and abrogates downstream angiogenic processes in human solid tumor cell lines.		Src
TP1516L	C-Reactive Protein (CRP) 77-82 acetate	C-Reactive Protein (CRP) 77-82 acetate(130349-01-8 free base)	Others
	C-Reactive Protein (CRP) 77-82 acetate is the 77-82 fragment of C-Reactive Protein. C-Reactive Protein (CRP), the prototypic marker of inflammation, is a cardiovascular risk marker and may promote atherogenesis.C-reactiv...		Others
T27255	Elubrixin HCl	SB656933,SB-656933AAF,SB-656933-AAF,SB 656933,SB-656933 AAF,SB-656933
	Elubrixin is a interleukin 8 inhibitor and CXCR2 selective antagonist.
T31877	Freselestat	ONO-PO 736,ONO-6818,ONO 6818,ONO6818
	Freselestat (ONO-6818) is a potent neutrophil elastase inhibitor that significantly reduces the production of interleukin 8 and C5B-9. Freselestat reduces inflammatory mediators during simulated cardiopulmonary bypass.
T69599	ABT-510
	ABT-510 is synthetic peptide that mimics the anti-angiogenic activity of the endogenous protein thrombospondin-1 (TSP-1). ABT-510 inhibits the actions of several pro-angiogenic growth factors important to tumor neovascul...
T78079	NF546 hydrate		P2Y Receptor
	NF546 (hydrate), a selective non-nucleotide P2Y11 agonist, exhibits a pEC50 value of 6.27 and induces interleukin-8 secretion from human monocyte-derived dendritic cells [1].		P2Y Receptor
T79256	DPP-4-IN-8
	DPP-4-IN-8 (compound 27) is a potent and selective inhibitor of dipeptidyl peptidase 4 (DPP4), with an inhibition constant (Ki) of 0.96 μM. It inhibits the dipeptidase activity of DPP4 in both Caco-2 and HepG-2 cells and...
T69451	R-130823
	R-130823 is a ighly selective inhibition against mitogen-activated protein kinase p38alpha (IC50=22 nM). The release of tumor necrosis factor-alpha, interleukin-1beta, -6 and -8 was inhibited in lipopolysaccharide-stimul...