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Search Results for " hydrolase "

20

Compounds

Cat No. Product Name Synonyms Targets
T40317 α/β-Hydrolase-IN-1
α/β-Hydrolase-IN-1 demonstrates exceptional potency, with MICs of 50 μM (25 μg/mL) against M. smegmatis and 16 μM (8.4 μg/mL) against M. tuberculosis H37Ra, establishing it as a superior compound in this class.
T83857 Soluble Epoxide Hydrolase PROTAC 1a sEH Proteolysis-targeting Chimera 1a,Soluble Epoxide Hydrolase Proteolysis-targeting Chimera 1a,sEH PROTAC 1a
Soluble epoxide hydrolase (sEH) PROTAC 1a is a proteolysis-targeting chimera (PROTAC) comprising a cereblon ligand linked to the sEH inhibitor t-TUCB via a linker, promoting selective sEH degradation and inhibiting its h...
T12974 Soluble epoxide hydrolase inhibitor Others
Soluble epoxide hydrolase inhibitor is a soluble epoxide hydrolase inhibitor (human soluble epoxide hydrolase (h-sEH) with pIC50 of 8.4).
T75409 Nucleoside hydrolase (IAGNH)
Nucleoside hydrolase (IAGNH), a type of glycosidase, facilitates the recycling of nucleobases and ribose by catalyzing the cleavage of the N-glycosidic bond in nucleosides.
T78174 Serine Hydrolase inhibitor-21 Others
Serine Hydrolase Inhibitor-21 (compound 8), a pyridine-based serine hydrolase inhibitor, exhibits a K i of 429 nM against BuChE, and shows promise for Alzheimer's disease research [1].
T7898 AUDA Epoxide Hydrolase
AUDA is an inhibitor of sEH(IC50 values of 18 and 69 nM for the mouse and human enzymes, respectively)
T7199 TPPU Epoxide Hydrolase
TPPU is a potent inhibitor of both human and mouse sEH (IC50 of 3.7 and 2.8 nM, respectively)
T14557 BI-1935 Epoxide Hydrolase
BI-1935 is an inhibitor of soluble epoxide hydrolase (sEH). For diseases related to cardiovascular disease.
TN6794 N-(3-methoxybenzyl)-octadecanamide Others
N-(3-methoxybenzyl)-octadecanamide deverts from Maca (Lepidium meyenii Walp.).
T17158 Trans-AUCB t-AUCB Epoxide Hydrolase
trans-AUCB (t-AUCB) is an effective and selective soluble epoxide hydrolase inhibitor (IC50s: 1.3 nM, 8 nM, 8 nM for hsEH, mouse sEH and rat sEH, respectively).
T10900 CUDA PPAR , Epoxide Hydrolase
CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively. CUDA selectively increases the activity of peroxisome proliferator-activated receptor (PPAR...
T14315 AR-9281 APAU Epoxide Hydrolase
AR-9281 (APAU) is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH) potentially for the treatment of hypertension and type 2 diabetes
T6043 PF-3845 FAAH , Autophagy
PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.
T11147 EC5026 BPN-19186 Epoxide Hydrolase
EC5026 (BPN-19186) has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators.
T28353 PDP-EA FAAH
PDP-EA is an activator of fatty acid amide hydrolase(FAAH) and enhances the amidohydrolase activity of FAAH.
T2684 JNJ-1661010 JNJ1661010,Takeda-25,JNJ 1661010 FAAH
JNJ-1661010 (Takeda-25) is an effective and specific FAAH inhibitor (IC50: 10/ 12 nM for rat/human), shows >100-fold selectivity for FAAH-1 than FAAH-2.
T9967 MAGL-IN-5 Lipid
MAGL-IN-5 is a non-selective lipase inhibitor.
T9374 AA38-3 1-Piperidinecarboxylic acid, 4-nitrophenyl ester FAAH , Lipase , MAGL
AA38-3 (1-Piperidinecarboxylic acid, 4-nitrophenyl ester) inhibites three SHs (ABHD6, ABHD11, and FAAH)
T8844 Diflapolin Others , FLAP , Epoxide Hydrolase
Diflapolin is a highly active dual 5-lipoxygenase-activating protein (FLAP)/soluble epoxide hydrolase (sEH) inhibitor with marked anti-inflammatory efficacy and high target selectivity.
T7688 4-Nonylphenylboronic acid FAAH
4-Nonylphenylboronic acid is a inhibitor of FAAH.
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TargetMol