store under nitrogen,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) is a vitamin B9 derivative that is a common one-carbon donor in organisms and is involved in growth and metabolism.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 30.00 | |
10 mg | In stock | $ 44.00 |
Description | Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) is a vitamin B9 derivative that is a common one-carbon donor in organisms and is involved in growth and metabolism. |
In vitro | In Adh5-/- DT40 cells, Tetrahydrofolic acid (0-200 µM; 3 days) resulted in a rapid drop in cell viability[1]. |
In vivo | In Adh5-/- mice, Tetrahydrofolic acid (62.5 mg/kg; intraperitoneal injection; daily) resulted in disrupted hematopoiesis, increased phosphorylation of Ser139-H2AX, and decreased survival of hematopoietic stem and progenitor cells (HSPCs)[1]. |
Synonyms | 5,6,7,8-tetrahydrofolic acid, folate-H4, Tetrahydropteroylglutamic acid, th-folate |
Molecular Weight | 445.43 |
Formula | C19H23N7O6 |
CAS No. | 135-16-0 |
store under nitrogen,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 1 mg/mL (2.25 mM), Sonication is recommended.
H2O: 1 mg/mL (2.25 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Tetrahydrofolic acid 135-16-0 Metabolism Endogenous Metabolite 5,6,7,8-tetrahydrofolic acid folate-H4 Tetrahydropteroylglutamic acid th-folate inhibitor inhibit