endothelin-1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T19309L1	Endothelin 1 (swine, human) acetate	Endothelin 1 (swine, human) acetate(117399-94-7 free base)	Endothelin Receptor
	Endothelin 1 (swine, human) acetate is a synthetic peptide with the sequence of human and swine Endothelin 1. Endothelin 1 is a potent endogenous vasoconstrictor and acts through two types of receptors ETA and ETB.		Endothelin Receptor
T22540L	Ac-Endothelin-1 (16-21), human acetate		Others
	Ac-Endothelin-1 (16-21), human acetate, the principal peptide of the endothelin family, has been shown to have a variety of biological activities in both vascular and nonvascular tissues. The C-terminal fragment, which i...		Others
T36480	Big Endothelin-1 (1-39), porcine
	The big endothelins comprise residues 53-90 (human big ET-1) and 53-91 (porcine big ET-1) of the endothelin precursor (preproendothelin). Compared to the mature endothelin-1 (ET-1), both peptides show less vasoconstricto...
T19309	Endothelin 1 (swine, human)		Others
	Endothelin 1 (swine, human), a synthetic peptide mirroring the sequence of both human and swine Endothelin 1, functions as a robust endogenous vasoconstrictor by interacting with two receptor types, ETA and ETB.		Others
T22540	Ac-Endothelin-1 (16-21), human		Others
	ENDOTHELIN-1 (ET-1), the principal peptide of the endothelin family, has been shown to have a variety of biological activities in both vascular and nonvascular tissues. The C-terminal fragment, which is a highly cons...		Others
TP2246	Endothelin-1 (1-15), amide, human		Others
	Endothelin-1 is one of the there isoforms of endothelin (identified as ET-1, -2, -3) with varying regions of expression and binding to at least four known endothelin receptors, ETA, ETB1, ETB2 and ETC.		Others
T36479	Big Endothelin-1 (1-38), human
	Human Big ET-1 comprises residues 53-90 of the endothelin precursor (preproendothelin). Compared to the mature endothelin-1 (hET-1), the peptide show less vasoconstrictor activity in vitro, but similar pressor effects in...
T76329	[Asn18] Endothelin-1, human
	[Asn18] Endothelin-1, human, a peptide, represents a predominant isoform of Endothelin, significantly contributing to the regulation of vascular function [1].
T15232	TBC3711	Endothelin Mordulator 1	Others
	TBC3711 is an endothelin receptor modulator. It is used for the research of endothelin-mediated disorders.		Others
T2026	CYM5442		S1P Receptor , LPL Receptor
	CYM5442 is an S1P agonist, targeting to Sphingosine.		S1P Receptor , LPL Receptor
T78063	Endothelin-1 (1-31) (Human) TFA		ERK
	Endothelin-1 (1-31) (Human) TFA, a potent vasoconstrictor and hypertensive agent, originates from the chymase-mediated selective hydrolysis of big ET-1 [1].		ERK
T76564	Endothelin-1 (1-31) (Human)
	Endothelin-1 (1-31) (Human) is a powerful vasoconstrictor and agent for inducing hypertension, originating from the specific hydrolysis of big ET-1 by chymase [1].
TP1512	[Ala1,3,11,15]-Endothelin TFA
	[Ala1,3,11,15]-Endothelin (TFA) is a highly selective for endothelin A (ETA) and endothelin B (ETB) receptor.[Ala1,3,11,15]-Endothelin is a selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for ...
T75731	Endothelin 1 (swine, human) (TFA)
	Endothelin 1 (swine, human) (TFA) is a synthetic peptide mirroring the sequence of the potent endogenous vasoconstrictor found in both human and swine Endothelin 1. It operates via two receptor types, ET A and ET B [1].
T76564L	Endothelin-1 (1-31) (Human) acetate
	Endothelin-1 (1-31) (Human) acetate, a potent vasoconstrictor and hypertensive agent, is produced through the selective hydrolysis of big ET-1 by chymase [1].
T82886	Big endothelin-1 (rat 1-39)
	Big endothelin-1 (rat 1-39), a 39-residue peptide, induces a diuretic and natriuretic response in conscious Sprague-Dawley rats and elevates blood pressure in mice [1].
T76081	Endothelin 1 (swine, human), Alexa Fluor 488-labeled
	Endothelin 1 (swine, human), Alexa Fluor 488-labeled, is a synthetic peptide corresponding to the sequence of human and swine Endothelin 1, a powerful endogenous vasoconstrictor, and is tagged with Alexa Fluor 488 for fl...
T6265	Bosentan (hydrate)	Bosentan Hydrate,Benzenesulfonamide,Actelion,Ro 47-0203	Endothelin Receptor
	Bosentan hydrate (Ro 47-0203) is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.		Endothelin Receptor
T6264	Bosentan	Actelion,Ro 47-0203,Benzenesulfonamide	Endothelin Receptor
	Bosentan (Benzenesulfonamide) is a sulfonamide-derived, competitive and specific endothelin receptor antagonist with a slightly higher affinity for the endothelin A receptor than endothelin B receptor. Bosentan blocks th...		Endothelin Receptor
T36008	Nebentan potassium
	Nebentan potassium (YM598) is a potent, selective and orally active non-peptide endothelin ETA receptor antagonist through the modification of Bosentan . Nebentan potassium inhibits [125I] endothelin-1 binding to cloned ...