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Search Results for " endogenously "

20

Compounds

Cat No. Product Name Synonyms Targets
T12192 NCGC00229600 Others , TSH Receptor
NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves' disease studies.
T38612 Linaprazan glurate Others
Linaprazan glurate inhibits exogenously or endogenously stimulated gastric acid secretion. Linaprazan glurate can be used in studies about gastrointestinal inflammatory diseases and peptic ulcer diseases.
T19023 Lucigenin NSC-151912,L-6868 Others
Lucigenin (NSC-151912) (L-6868) is a chemiluminescent probe used to indicate the presence of endogenously generated superoxide anion radicals in cells.
T7224 Anabasine (S)-Anabasine,(-)-Anabasine AChR
Anabasine ((S)-Anabasine) is an alkaloid extracted from tobacco. Anabasine is a full agonist of nicotinic acetylcholine receptors (nAChRs) with insecticidal activity. Anabasine depolarizes TE671 cells endogenously expres...
T5089 5-Aminovaleric acid Others , Endogenous Metabolite
5-aminovalerate (or 5-aminopentanoic acid) is a lysine degradation product. It can be produced both endogenously or through bacterial catabolism of lysine. 5-aminovalerate is formed via the following multi-step reaction:...
T6926 Palmitoylethanolamide Mackpeart DR 14V,N-palmitoylethanolamine,Loramine P 256,Impulsin,AM 3112,Palmidrol Influenza Virus , Endogenous Metabolite , PPAR
Palmitoylethanolamide (Impulsin) is an endogenously fatty acid amide. It has a role as an anti-inflammatory drug, an antihypertensive agent, a neuroprotective agent and an anticonvulsant.Upon administration, palmitoyleth...
T5303 Isethionic acid sodium salt Sodium isethionate Others , Endogenous Metabolite
Isethionic acid sodium salt (Sodium isethionate) is an organosulfur compound containing a short chain alkane sulfonate linked to a hydroxyl group. Mammals are able to endogenously synthesize Isethionic acid sodium salt v...
T5302 (R)-pyrrolidine-2-carboxylic acid D-Proline Others , Endogenous Metabolite
(R)-pyrrolidine-2-carboxylic acid (D-Proline) is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva. These amino acids may be...
T2563 Acetyl-L-carnitine hydrochloride Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride Others , Endogenous Metabolite
Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) is a nutritional supplement composed of the hydrochloride salt form of the acetylated form of the endogenously produced L-carnitine, with potential neur...
T19039 NIR-Thiol dinitrobenzenesulfonate Others
NIR-Thiol dinitrobenzenesulfonate has both absorption and emission in the NIR region. It is capable of imaging endogenously produced thiol in living cells and mice.
T36833 A6770
A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.1It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P l...
T71212 Lornoxicam-d4
Lornoxicam-d4 is intended for use as an internal standard for the quantification of lornoxicam by GC- or LC-MS. Lornoxicam is a COX inhibitor and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and an...
T28140 NCG21 NCG-21,NCG 21
NCG21 is a GPR120 agonist, which showed potent extracellular signal-regulated kinase (ERK) activation in a cloned GPR120 system. NCG21 potently activated ERK, intracellular calcium responses and GLP-1 secretion in murine...
T37409 DPC-AJ1951 (trifluoroacetate salt) DPC-AJ1951 (trifluoroacetate salt)
DPC-AJ1951 is a peptide agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR; EC50 = 0.15 nM in HEK293 cells expressing human PPR). It induces cAMP production in SAOS-2 and UMR106 cells that endogen...
T37634 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils. 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by asp...
T37633 17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid
17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DHA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2...
T36051 Lipoxin A4 LXA4
Lipoxin A4 (LXA4) is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of (±)15-HETE or 15-HpETE with human leukocytes.[1] LXA4 is equipotent to leukotriene B4 in inducing superoxide g...
T37199 Bilaid C
Bilaid C is a tetrapeptide μ-opioid receptor agonist (Ki= 210 nM in HEK293 cell membranes expressing the human receptor) that has been found inPenicillium.1It inhibits forskolin-induced cAMP accumulation by 77% in HEK293...
T82771 CB2-H
CB2-H is a dual-channel fluorescent probe designed for the concurrent detection of HOCl and ONOO- with two separate channels that avoid spectral cross-interference. It facilitates dual-channel fluorescence imaging to mon...
T37503 Maresin 2 3R,14S-diHDHA
Docosahexaenoic acid is an ω-3 fatty acid that is abundant in the brain and the retina and is known to be important in early development.[1] [2] Maresin 2 (MaR2) is a 13R,14S-dihydroxy DHA formed by recombinant human mac...
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