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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T21658 | ARN14974 | Others | |
ARN14974 is a benzoxazolone carboxamide. ARN14974 is a potent inhibitor of acid ceramidase with IC50 of 79 nM[1]. | |||
T0333 | Aniracetam | Ro 13-5057 | Dopamine Receptor , 5-HT Receptor , GluR , AChR , iGluR |
Aniracetam (Ro 13-5057)(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR. | |||
T38715 | MSDC-0602K | MSDC-0602K,Azemiglitazone potassium | PPAR |
MSDC-0602K (Azemiglitazone potassium) (Azemiglitazone potassium) is a PPARγ-sparing thiazolidinedione (Ps-TZD) compound that binds to PPARγ with an IC50 of 18.25 μM. It also modulates the mitochondrial pyruvate carrier (... | |||
T23709 | AlphaSYN-IN-NAB2 | alphaSYN inhibitor NAB2,alphaSYNINNAB2,alphaSYN-IN-NAB2,NAB2,alphaSYN inhibitor-NAB2 | |
alphaSYN-IN-NAB2, a neuron-protective agent, is a protein encoded by the NAB2 gene. NAB2 effectively and selectively protects a variety of cells from alpha-SYN toxicity. NAB2 promotes endosomal transport dependent on E3 ... | |||
T71243 | ASP3662 | ||
ASP3662, also known as SPI-62, is a potent, selective and CNS-penetrable inhibitor of 11β-HSD1. The effects of ASP3662 suggest that selective inhibition of 11β-HSD1 may be an attractive approach for the treatment of neu... | |||
T79358 | PF-07247685 | Endogenous Metabolite | |
PF-07247685, a potent BCKDC kinase (BDK) inhibitor (EC 50 = 2.2 nM), enhances the binding between BDK and the BCKDH E2 core subunit to block E1 phosphorylation. BDK regulation is crucial for BCKDH activity, which manages... |