convulsant — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2850	Bicuculline	(+)-Bicuculline,d-Bicuculline	GABA Receptor
	Bicuculline ((+)-Bicuculline) is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungos...		GABA Receptor
T73586	Anticonvulsant agent 2		Others
	Anticonvulsant agent 2 is a potent orally active anticonvulsant that has shown antiepileptic activity in a model of drug-resistant epilepsy.		Others
T10027	Anticonvulsant agent 1	4-(2,2-Difluoroethenyl)-α-ethyl-2-oxo-1-pyrrolidineacetamide	Others
	Anticonvulsant agent 1 is an anticonvulsant compound.		Others
T1017	Fluorothyl	Fluoroethyl,Flurothyl,Bis(2,2,2-trifluoroethyl) ether	Others
	Fluorothyl (Bis(2,2,2-trifluoroethyl) ether) is a convulsant used in experimental animals.		Others
T16844	Sarmazenil	R-154513,Ro 15-3505	GABA Receptor
	Sarmazenil (Ro 15-3505) is a partial inverse agonist at the benzodiazepine receptor with pro-convulsant properties and is used in the study of chronic hepatic encephalopathy (HE).		GABA Receptor
T11106	DSP-0565	2-(2'-fluorobiphenyl-2-yl)acetamide	Others
	DSP-0565 exhibits anti-convulsant activity and good safety margin in various models including scPTZ, 6 Hz, MES, and amygdala kindling. DSP-0565 can be used in studies about acting as a broad-spectrum anti-epileptic drug.		Others
T41299	L-Methionine-DL-sulfoximine	MSX,MSO	Others
	L-Methionine-DL-sulfoximine (MSO) inhibits glutamine synthetase and metabolically and morphologically primarily affects astroglia. L-Methionine-DL-sulfoximine can be used in convulsant studies.		Others
T16535	Picrotoxinin		Chloride channel , GABA Receptor
	Picrotoxinin is a blocker of chloride channel and a noncompetitive antagonist of GABAA with an IC50 of 1.15 μM for α1β2γ2L GABAA. Picrotoxinin shows convulsant properties.		Chloride channel , GABA Receptor
T0958	Penicillin G sodium salt	Penicillin G Sodium,Benzylpenicillin sodium salt,Benzylpenicillin Sodium	GABA Receptor , Antibacterial , Antibiotic
	Penicillin G sodium(Benzylpenicillin sodium) salt is a penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-posit...		GABA Receptor , Antibacterial , Antibiotic
T2S1464	Thiocolchicoside	Thiocolchicine 2-glucoside analog,Coltramyl	Others , GABA Receptor
	Thiocolchicoside (Thiocolchicine 2-glucoside analog) (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine rece...		Others , GABA Receptor
T2S2108	Coixol	6-methoxybenzoxazolone,6-MBOA,6-Methoxy-2-benzoxazolinone,MBOA	Others , Antibacterial
	1. Coixol (MBOA) acts as a central muscle relaxant with an anti-convulsant effect. 2. Coixol interacts with the pituitary to stimulate reproduction in voles. 3. Coixol has the ability to interact with FSH to stimulate fo...		Others , Antibacterial
T37190	L-Allylglycine		Dehydrogenase , GABA Receptor
	L-Allylglycine is an amino acid derivative that reduces glutamate decarboxylase (GAD) activity by 60% when administered at a dose of 39.8 μmol/g per hour ex vivo in mouse brain preparations. L-Allylglycine (1.2 mmol/kg, ...		Dehydrogenase , GABA Receptor
T28624	RU5135	RU 5135,RU-5135
	RU5135 is a novel convulsant amidine steroid which inhibits gamma-aminobutyric acid receptor binding.
T70016	Methionine sulfoximine
	Methionine sulfoximine (MSO) is an irreversible glutamine synthetase inhibitor. It is the sulfoximine derivative of methionine with convulsant effects.
T39387	Xanthine amine congener dihydrochloride	XAC dihydrochloride,Xanthine amine congener dihydrochloride
	Xanthine amine congener dihydrochloride (XAC dihydrochloride), a potent antagonist for both Adenosine A1 and A2 receptors, exhibits IC50 values of 1.8 nM for A1 and 114 nM for A2 receptors. Additionally, it functions as ...