capsid — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T16366	NVR 3-778		HBV
	NVR 3-778 is a first-in-Class and oral bioavailable HBV CAM belonging to the SBA class It has anti-HBV activity.		HBV
T11465	Lenacapavir	GS-6207	Others , HIV Protease
	Lenacapavir (GS-6207) is a potent capsid-targeting inhibitor of HIV replication. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells.		Others , HIV Protease
T16500	PF-3450074	PF-74	HIV Protease
	PF-3450074 (PF-74) acts at an early stage of HIV-1 infection inhibits viral replication by directly competing with the binding of CPSF6 (nuclear host factors cleavage and polyadenylation specific factor 6) and NUP153 (nu...		HIV Protease
T9054	RO6889678		HBV
	RO6889678 is HBV inhibitor with a complex ADME profile.		HBV
T6439	Cetylpyridinium Chloride	Cetamium,Pristacin,Hexadecylpyridinium Chloride	Others , HBV , Antibacterial
	Cetylpyridinium Chloride (Hexadecylpyridinium Chloride) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.		Others , HBV , Antibacterial
T4536	Pleconaril	VP 63843,Win 63843,Picovir	Virus Protease , Antiviral
	Pleconaril (VP 63843) is a capsid inhibitor used previously to treat enterovirus infections. Pleconaril is effective in inhibiting replication (IC50: 50 nM).		Virus Protease , Antiviral
T4475	JNJ-632		HBV
	JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator.		HBV
T3345	Hederasaponin B	Eleutheroside M,Hederacoside B	Others , Virus Protease
	Hederasaponin B (Hederacoside B) has antiviral activity, via inhibiting the viral VP2 protein expression and blocking viral capsid protein synthesis.		Others , Virus Protease
TQ0017	AB-423		HBV
	AB-423 is an inhibitor of HBV capsid assembly, and potently inhibits HBV replication (EC50/EC90: 0.08-0.27 μM/0.33-1.32 μM in cells).		HBV
T20000	I-XW-053		HIV Protease
	I-XW-053 is a capsid targeted HIV-1 replication inhibitor.		HIV Protease
T27221	DVR-01	3-(azepan-1-ylsulfonyl)-N-benzyl-4-chlorobenzamide	HBV
	DVR-01 is an HBV capsid inhibitor and can be used in studies about the treatment of Hepatitis B virus (HBV) infection and related conditions.		HBV
T1750	Pirodavir	R77975	Virus Protease , Antiviral
	Pirodavir (R77975) (R 77975), the prototype of broad-spectrum anti-picornavirus compounds, is a potent human rhinovirus (HRV) capsid-binding inhibitor.		Virus Protease , Antiviral
T4492	Pocapavir	SCH-48973,V-073	Virus Protease , Antiviral
	Pocapavir (SCH-48973) is an investigational enterovirus (EV) capsid inhibitor.		Virus Protease , Antiviral
T5782	Bevirimat	YK FH312,MPC-4326,PA-457	HIV Protease
	Bevirimat (PA-457) is a first-in-class inhibitor of HIV-1 maturation, blocking the cleavage of the Gag capsid (CA) precursor, CA-SPI, to mature CA protein during virion maturation.		HIV Protease
TP1739L	HEX3 acetate(688805-40-5 free base)		Others
	HEX3 acetate is a fragment of the adenoviral hexon. Hexon is the major capsid protein of adenovirion and is comprised of three identical polypeptide chains.		Others
T11409	GLP-26		HBV
	GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools. GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM...		HBV
T28860	ST-148	ST148
	ST-148 is a potent inhibitor for Dengue virus capsid. ST-148-enhanced capsid protein self-interaction perturbs assembly and disassembly of DV nucleocapsids, probably by inducing structural rigidity.
T71799	CAP-1
	CAP-1 is an inhibitor of HIV-1 capsid formation.
T26756	BCM-599	BCM 599
	BCM-599 is a HBV capsid assembly inhibitor. BCM-599 showed IC50 of 0.88 μM and CC50 of 144 μM in HepG2.2.15 cells.
T13284	Vapendavir diphosphate	BTA798 diphosphate	Others
	Vapendavir diphosphate is a potent enteroviral capsid binder (CB) and has a potent antiviral activity for enterovirus 71 (EV71) replication (EC50: 0.5-1.4 μM in different EV71 strains).		Others