anxiety-like — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T16421	P-MPPI hydrochloride		5-HT Receptor
	p-MPPI hydrochloride is a selective antagonist of 5-HT1A receptor, and has antidepressant and anxiolytic-like effects.		5-HT Receptor
T7644	DPN	Diarylpropionitrile	Apoptosis , Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Autophagy
	DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .
T23444	TCS 1105	N-(4-fluorobenzyl)-2-(1H-indol-3-yl)-2-oxoacetamide	Others
	TCS 1105 is a GABAA benzodiazepine receptor (BZR) ligand. TCS 1105 blocks Sema3A induced axonal growth cones collapse. TCS 1105 reduces anxiety-like behavior and enhances offensive behavior and social dominance in mice.		Others
T5828	MS21570		GPR
	MS21570 as a GPR171 antagonist based on its ability to block,with an IC50 of 220 Nm,that reduces anxiety-like behavior and fear conditioning in mice.		GPR
T35707	3'-Sialyllactose sodium	3'-SL sodium	NF-κB
	3'-Sialyllactose sodium is a prebiotic with anti-inflammatory activity that maintains immune homeostasis. 3'-Sialyllactose sodium reduces stressor-induced anxiety-like behaviors and can be used in studies of inflammation...		NF-κB
T16401	Org-12962		5-HT Receptor
	Org-12962 is an effective and selective 5-HT2C receptor agonist pEC50: 7.01). Org-12962 shows antiaversive effects in a rat model of panic-like anxiety. Org-12962 also shows high effacy for the 5-HT2A and 5-HT2B receptor...		5-HT Receptor
T2940	6-Hydroxyflavone	6-HF	GABA Receptor
	6-Hydroxyflavone (6-HF) is a noncompetitive inhibitors of cytochrome P450 2C9. It is a flavone, a type of chemical compound. It is reported in leaves of Barleria prionitis Linn. (a common Acanthaceae from India). 6-Hydro...		GABA Receptor
TP1982	Neuropeptide S(Rat)	Neuropeptide S (Rat)
	Potent endogenous neuropeptide S receptor (NSPR) agonist (EC50 = 3.2 nM). Increases locomotor activity and wakefulness in mice. Also reduces anxiety-like behavior in mice.
TP1983	Neuropeptide S (human)
	Potent endogenous neuropeptide S receptor agonist (EC50 = 9.4 nM). Increases locomotor activity and wakefulness in mice. Also reduces anxiety-like behavior in mice.
T75951	Neuropeptide S(Rat) TFA
	Neuropeptide S(Rat) TFA, a robust endogenous agonist for the neuropeptide S receptor (NSPR) with an EC50 of 3.2 nM, enhances locomotor activity and promotes wakefulness while concurrently diminishing anxiety-like behavio...
TP1981	Neuropeptide S(Mouse)	Neuropeptide S (Mouse)
	Potent endogenous neuropeptide S receptor (NPSR) agonist (EC50 = 3 nM). Induces mobilization of intracellular Ca2+. Increases locomotor activity and wakefulness in mice. Also reduces anxiety-like behavior in mice.
T75950	Neuropeptide S(Mouse) TFA
	Neuropeptide S(Mouse) TFA, an endogenous agonist for the neuropeptide S receptor (NPSR) with an EC50 value of 3 nM, plays a significant role in physiological processes by inducing the mobilization of intracellular Ca2+. ...
T83665	α-Helical CRF (9-41) TFA	α-Helical Corticotropin-Releasing Factor (9-41)
	α-Helical CRF (9-41) is a synthetic peptide antagonist that targets corticotropin-releasing factor (CRF), effectively inhibiting CRF-induced adrenocorticotropic hormone (ACTH) release both in vitro, with isolated rat ant...
T37114	SB 242084 dihydrochloride
	SB 242084 hydrochloride is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively.IC50 value: 9.0(pKi) [1]Target: 5-HT2C antagonistin vitro: SB 242...
T38145	Eltoprazine
	Eltoprazine(DU28853) is a serenic or antiaggressive agent which as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor.IC50 value:Target: 5-HT1A/1B agonist; 5-HT2C antagonistin vitro...