acinetobacter — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1101	Minocycline hydrochloride	Minocycline HCl	HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
	Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochlor...		HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
T37746	N-phenylacetyl-L-Homoserine lactone		Others
	N-phenylacetyl-L-Homoserine lactone attenuates the group sensing of the pathogen Acinetobacter baumannii and can be used to study bacterial infections.		Others
T11125	Durlobactam sodium salt	ETX2514 sodium salt	Antibacterial
	Durlobactam sodium salt (ETX2514 sodium salt) is an inhibitor of β-lactamase with IC50 values of 4 nM, 14 nM, and 190 nM for Class A KPC-2, Class C AmpC, and Class D OXA-24, respectively. Durlobactam sodium salt can be u...		Antibacterial
T1569	Tigecycline	GAR-936	ribosome , Antibacterial , Antibiotic , Autophagy
	Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome co...		ribosome , Antibacterial , Antibiotic , Autophagy
T14492	BAL-30072		Others
	BAL30072 shows MIC90 values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively[1][2]. BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against m...		Others
T39983	SPR206 acetate
	SPR206 acetate is a polymyxin analog that exhibits antibiotic activity against Gram-negative pathogens, including multidrug-resistant (MDR) variants. By interacting with the outer membrane of the bacterium, SPR206 acetat...
T75279	Tigecycline tetramesylate
	Tigecycline tetramesylate (GAR-936 tetramesylate), a broad-spectrum glycylcycline antibiotic, exhibits a mean inhibitory concentration (MIC) for E. coli (MG1655 strain) of approximately 125 ng/mL [1]. For Acinetobacter b...
T68438	APO-6619
	APO-6619 is an iron chelator which was shown to inhibit growth of the following bacterial strains: Acinetobacter baumannii, Pseudomonas aeruginosa, Staphylococcus aureus, Klebsiella pneumoniae, and Escherichia coli. AP...
T61042	TBT1
	TBT1 is a MsbA ATPase stimulator and an LPS transport inhibitor in Acinetobacter strains. The EC50 value of TBT1 stimulated ATPase activity is 13 μM. TBT1 is a first-generation inhibitor of the MsbA transporter [1].
T39296	DS86760016
	DS86760016 is a highly effective inhibitor of leucyl-tRNA synthetase (LeuRS), demonstrating potent activity against multidrug-resistant (MDR) Gram-negative bacteria including Escherichia coli, Klebsiella pneumoniae, and ...
T74866	Antibacterial agent 116
	Antibacterial agent 116, a benzophenone-containing salicylanilide compound, exhibits potent antibacterial activity by inhibiting peptidoglycan formation. It is employed as a photoaffinity probe to label Acinetobacter bau...
T74341	Antibacterial agent 71
	The compound demonstrates enhanced potency against wild-type (WT) strains of Escherichia coli, Acinetobacter baumannii, and Burkholderia cenocepacia, showing significant improvements of up to (>128-fold) due to increased...
T73798	Colistin
	Colistin (Polymyxin E), a polypeptide antibiotic with oral activity, exhibits strong efficacy against a range of Gram-negative rod-shaped bacteria, such as multidrug-resistant Pseudomonas aeruginosa, Acinetobacter bauman...
T79240	DNA gyrase B-IN-2
	DNA gyrase B-IN-2 (Compound E), a 2-aminobenzothiazole derivative, serves as a potent inhibitor of DNA gyrase B with substantial efficacy against ESKAPE pathogens. The compound exhibits potent nanomolar-range inhibition ...
T12991	SPR206		Others
	SPR206 is a polymyxin analogue and an important class of antibiotic for the treatment of bacterial infections due to multidrug resistant Gram-negative pathogen.		Others