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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T23523 | W-5 hydrochloride | W-5 HCl,W 5 (hydrochloride),N-(6-Aminohexyl)-1-naphthalenesulfonamide HCl | CaMK |
W-5 hydrochloride (N-(6-Aminohexyl)-1-naphthalenesulfonamide HCl) is a potent calmodulin antagonist. | |||
T9766 | GW590735 | PPAR | |
GW590735 is an effective and selective PPARα agonist with an EC50 of 4 nM on PPARα and at least 500-fold selectivity versus PPARδ and PPARγ. GW590735 can be used in dyslipidemia studies. | |||
T6080 | NVP-AEW541 | AEW541 | FLT , Tyrosine Kinases , IGF-1R , Autophagy |
NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-based assay. | |||
TP2131L | Rac1 Inhibitor W56 acetate(1095179-01-3 free base) | Rho | |
Rac1 Inhibitor W56 acetate(1095179-01-3 free base) is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1. Rac1 Inhibitor W56 acetate(1095179-01-3 free ... | |||
T69408 | GW590735 sodium | ||
GW590735 is a potent and selective agonist of PPARα with an EC50 value of 4 nM for the expression a GAL4-responsive reporter gene and at least 500-fold selectivity versus PPARγ and PPARδ. GW590735 significantly increased... | |||
T71082 | DW532 | ||
DW532 is one of simplified analogues of hematoxylin that has shown broad-spectrum inhibition on tyrosine kinases and in vitro anti-cancer activities. DW532 inhibited EGFR and VEGFR2 in vitro kinase activity (the IC50 val... | |||
T18106 | M-PEG-OH (MW5000) | Others | |
m-PEG-OH (MW5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | |||
T75932 | Rac1 Inhibitor W56 TFA | ||
Rac1 Inhibitor W56 TFA, a peptide comprised of residues 45-60 of Rac1, selectively obstructs Rac1's interaction with the guanine nucleotide exchange factors TrioN, GEF-H1, and Tiam [1]. | |||
T27510 | GW568377A | ||
GW568377A is an inhibitor of Mer Kinase and EGFR. | |||
T69682 | AEW541 HCl | ||
AEW541, also known as NVP-AEW541, is a novel, potent IGF-IR kinase inhibitor. NVP-AEW541 is capable of distinguishing between the IGF-IR (IC50 = 0.086 microM) and the closely related InsR (IC50 = 2.3 microM) in cells. NV... | |||
T83901 | BDW568 | ||
BDW568, a prodrug of BDW-OH, serves as a stimulator of interferon genes (STING) agonist. This compound effectively induces STING transcriptional activity, evidenced by a reporter assay in THP-1 cells, with an EC50 value ... | |||
TP2131 | Rac1 Inhibitor W56 | ||
Rac1 Inhibitor W56 is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1. Rac1 Inhibitor W56 selectively inhibits Rac1 interaction with Rac1-specific G... |