verapamil — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T20656	Verapamil	NSC 135784,NSC-135784,CP-16533-1,(±)-Verapamil	P450 , Calcium Channel , P-gp
	Verapamil (CP-16533-1) is a calcium channel blocker and an orally active and effective inhibitor of P-gp. Verapamil inhibits CYP3A4 and can be used in studies about the treatment of high blood pressure, heart arrhythmias...		P450 , Calcium Channel , P-gp
T1010	Verapamil hydrochloride	Manidon,(±)-Verapamil hydrochlorid,Verapamil HCl,Calcan hydrochloride	P450 , Calcium Channel , P-gp
	Verapamil hydrochloride (Verapamil HCl) is a calcium channel blocker that is a class IV anti-arrhythmia agent.		P450 , Calcium Channel , P-gp
T12646	(R)-Verapamil hydrochloride	(R)-(+)-Verapamil hydrochloride	Others
	(R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is a inhibitor of P-Glycoprotein.		Others
T13879	(S)-Verapamil hydrochloride	(S)-(-)-Verapamil hydrochloride	Calcium Channel
	(S)-Verapamil hydrochloride is an inhibitor of leukotriene C4 (LTC4) and calcein transport by MRP1,and leads to the death of potentially resistant tumor cells.		Calcium Channel
T40591	Verapamil EP Impurity C hydrochloride	NSC-609249 hydrochloride
	NSC-609249 hydrochloride, an impurity of Verapamil, is a calcium channel blocker with potent orally active properties. It also functions as a first-generation P-glycoprotein (P-gp) inhibitor.
T11353	Gallopamil	Methoxyverapamil	Calcium Channel
	Gallopamil (Methoxyverapamil) inhibits acid secretion in a concentration-dependent manner with an IC50 of 10.9 μM. Gallopamil is a potent antiarrhythmic and vasodilator agent. Gallopamil (Methoxyverapamil), a methoxy der...		Calcium Channel
T11353L	Gallopamil hydrochloride	Methoxyverapamil hydrochloride	Calcium Channel
	Gallopamil hydrochloride (Methoxyverapamil hydrochloride) is an antagonist of phenylalkylamine calcium. Gallopamil hydrochloride can be used in antiarrhythmic and vasodilator studies.		Calcium Channel
T16339	Norverapamil hydrochloride	(±)-Norverapamil hydrochloride,D591 hydrochloride	Calcium Channel , P-gp , Drug Metabolite
	Norverapamil hydrochloride (D591 hydrochloride) ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor.		Calcium Channel , P-gp , Drug Metabolite
T30146	Arverapamil	(R)-Norverapamil,Agi-003,UNII-3J8P56R04P,Rezular
	Arverapamil is a chiral metabolite of Verapamil.
T69317	Dexverapamil
	Dexverapamil is the R-enantiomer of the calcium channel blocker verapamil. Dexverapamil competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1), thereby potentially increasing the effectiveness...
T12244	Norverapamil	D591,(±)-Norverapamil	Calcium Channel
	Norverapamil is a blocker of L-type calcium channel and an inhibitor of P-glycoprotein (P-gp) function .		Calcium Channel
T12243	Norverapamil-d7	D591 D7,(±)-Norverapamil D7	Others
	Norverapamil D7 is a deuterium labeled Norverapamil . Norverapamil is a blocker of L-type calcium channel and an inhibitor of P-glycoprotein (P-gp) function .		Others
T0563	Homoveratronitrile		Others
	Homoveratronitrile is an impurity of Verapamil. It is also an intermediate in the preparation of the muscle relaxant Papverine.		Others
TCS0102	Pulegone	(+)-Pulegone	Calcium Channel , Endogenous Metabolite , TRP/TRPV Channel
	1. Pulegone ((+)-Pulegone) has cytotoxicity followed by regenerative cell proliferation is the MOA for Pulegone-induced urothelial tumors in female rats. 2. Pulegone induces a verapamil-sensitive psychostimulant effect t...		Calcium Channel , Endogenous Metabolite , TRP/TRPV Channel
T26120	Ronipamil	Ronipamilo
	Ronipamil is an analogue of verapamil that used as a calcium entry blocker.
T32912	Lu49888 HCl	Azidopamil,LU49888,LU 49888,Ludopamil,LU-49888
	LU 49888 is a photoaffinity analog of verapamil that has been used to identify specific binding sites for phenylalkylamines of calcium channels present in rabbit skeletal muscle microsomes.
T69956	KR30031
	KR30031 is a novel P-glycoprotein inhibitor with potential anticancer activity. KR30031 is a verapamil analog with fewer cardiovascular effects. The ability of KR-30031 to reduce this efflux transport is equal to that of...
T27302	Falipamil	AQ-A 39,AQ-A-39,AQ-A39
	Falipamil is a verapamil derivative and a calcium channel antagonist. Falipamil exerts antitachycardic effects by a direct action on the sinus node. Falipamil decreases HR at exercise in normal subjects and may exert ant...
TN2726	Jatrophane 5		P-gp
	Jatrophane 5 demonstrates the most powerful inhibition of P-gp, higher than R(+)-verapamil and tariquidar in colorectal multi-drug resistant (MDR) cells (DLD1-TxR).		P-gp
TN2727	Jatrophane 2		P-gp , Antifection
	2,5,7,8,9,14-Hexaacetoxy-3-benzoyloxy-15-hydroxyjatropha-6(17),11E-diene (Jatrophane 2 ) exhibits significant antifeedant activity against a generalist plant-feeding insect, the cotton bollworm (Helicoverpa armigera). Ja...		P-gp , Antifection