urokinase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3722	MK-1064	Urokinase inhibitor 1,MK 1064	OX Receptor
	MK-1064 (Urokinase inhibitor 1) is a selective orexin 2 receptor antagonist (2-SORA).		OX Receptor
T73701	Urokinase (peptidolytic)
	Urokinase peptidolytic (Urokinase-type plasminogen activator) is a serine protease, an inactive form (zymogen) of the serine protease plasminogen. Activation of plasmin triggers a proteolytic cascade reaction, which in t...
T13408	ZK824190		Others , Serine Protease
	ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA) as a potential treatment for multiple sclerosis(IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively).		Others , Serine Protease
T8362	Benzamidine hydrochloride	Benzamidine HCl	Serine/threonin kinase , Serine Protease
	Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, respectively).		Serine/threonin kinase , Serine Protease
T21703	4-Chlorophenylguanidine hydrochloride		Others
	4-Chlorophenylguanidine hydrochloride is a potent inhibitor of urokinase selectivity.		Others
T13257	Upamostat		PAI-1 , Serine/threonin kinase , Serine Protease
	Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.		PAI-1 , Serine/threonin kinase , Serine Protease
TP2338L	Cenupatide acetate	Cenupatide acetate(1006388-38-0 Free base)	Others
	Cenupatide acetate is an urokinase plasminogen activator receptor (uPAR) inhibitor for treating disorders associated altered cell migration, such as cancer.		Others
T60248	4-Aminobenzamidine dihydrochloride	p-Aminobenzamidine dihydrochloride	Serine Protease
	4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase type plasminogen activator (uPA) (K i =82 μM). 4-Aminobenzamidine can inh...		Serine Protease
T26629	Angstrom6	A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide	PAI-1
	Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascade and abrogates the downstream effects.Angstrom6 has antitumor a...		PAI-1
T6S1699	Shogaol	[6]-Shogaol,6-Shogaol	Lipoxygenase , Autophagy
	1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the f...		Lipoxygenase , Autophagy
T13251	UKI-1	UKI-1C	Others
	UKI-1 is a urokinase-type plasminogen activator system synthetic inhibitor.		Others
T30911	Chromozym U
	Chromozym U can be used as a chromogenic substrate test for urokinase in Shigella.
T22600	BC 11 hydrobromide		Others
	The compound is a selective urokinase inhibitor (IC50 = 8.2 μM). It also inhibits clot lysis with no effect on clot formation.		Others
T13409	ZK824859		Others
	ZK824859 is an oral available and selective inhibitor of urokinase plasminogen activator (uPA)(IC50s of 79 nM, 1580 nM and 1330 nM for human uPA, tPA, and plasmin, respectively).		Others
T69751	UK-356202
	UK-356,202 is a potent and selective urokinase-type plasminogen activator (Ki = 37 nM). Urokinase plasminogen activator (uPA, urokinase) is a trypsinlike serine protease and a therapeutical target for many cancer types, ...
T70927	UCD74A HCl
	UCD74A HCl is a cell impermeant homolog of UCD38B, inhibitor of uPA (urokinase plasminogen activator).
T35931	GGACK (hydrochloride)
	GGACK is an inhibitor of urokinase-type plasminogen activator (uPA) and factor Xa (Kis = 1.8 and 8.7 μM, respectively).1,2 1.Kettner, C., and Shaw, E.The susceptibility of urokinase to affinity labeling by peptides of ar...
T22451	UK-371804 HCl		Serine Protease
	UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (2700-fold versus plasmin and 4000-fold versus tPA).		Serine Protease
T13409L	ZK824859 hydrochloride (2271122-53-1 free base)	ZK824859 hydrochloride	Others
	ZK824859 hydrochloride is an oral available and selective inhibitor of urokinase plasminogen activator (uPA)(IC50s of 79 nM, 1580 nM and 1330 nM for human uPA, tPA, and plasmin, respectively).		Others
T41085	UK122	UK122
	UK122 is a highly effective and specific inhibitor of urokinase-type plasminogen activator (uPA) with an IC50 value of 0.2 μM. It displays negligible to minimal inhibition towards tissue-type plasminogen activator (tPA),...