thioredoxin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1604L	Thioredoxin reductase peptide acetate	Thioredoxin reductase peptide acetate(950890-23-0 free base)	Others
	Thioredoxin reductase peptide acetate corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research.Mammalian thioredoxin reductase (TR) catalyzes the reduction of the redox-active...		Others
TP1604	Thioredoxin reductase peptide
	Thioredoxin reductase peptide corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research.Mammalian thioredoxin reductase (TR) catalyzes the reduction of the redox-active disulfi...
TP1375	Thioredoxin reductase peptide TFA
	Thioredoxin reductase peptide TFA corresponds to residues 53-67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research..
T13230	TXNIP-IN-1		Others
	TXNIP-IN-1 is an inhibitor of the TXNIP-TRX complex and used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease, or inflammatory disease.		Others
T5481	TRi-1		Others
	TRi-1 is irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy		Others
T20168	Aurothiomalate sodium	Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate	Others , PKC
	Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate sodium (Miochrysin) is a potent and selective inhibitor of oncogenic PKC-ι signaling. Aurothiomalate ...		Others , PKC
T9118	KEA1-97		Apoptosis , Others , Caspase
	Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M). Kea1-97 destroys the interaction between thioredoxin and caspase 3 and activates caspases without affecting the activity ...		Apoptosis , Others , Caspase
T4414	Eprenetapopt	APR-246,PRIMA-1Met	Apoptosis , Others , Ferroptosis , p53 , Autophagy
	Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells. PRIMA-1MET also targets the selenoprotein thioredoxin reductase 1 (TrxR1), a key regulator of c...		Apoptosis , Others , Ferroptosis , p53 , Autophagy
T5372	L-SelenoMethionine	L-(+)-Selenomethionine	Apoptosis , Amino Acids and Derivatives , Endogenous Metabolite
	L-SelenoMethionine (L-(+)-Selenomethionine) is a naturally occurring amino acid. It promotes cell cycle progression and elevates the expression of the antioxidant enzymes thioredoxin reductase, glutathione reductase.
T60446	LCS3		Apoptosis , Glutathione reductase
	LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3 μM and 3.8 μM, respectively. LCS3 has antitumour activity, in...		Apoptosis , Glutathione reductase
T2283	PX-12	IV-2,PX12	Thioredoxin
	PX-12 (PX12) (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits tumor gr...		Thioredoxin
T29018	TrxR inhibitor D9	D9,TrxR-IN-D9
	TrxR-IN-D9 is a novel inhibitor of thioredoxin reductase (TrxR).
T23166	PMX 464		Others
	inhibitor of the thioredoxin-thioredoxin reductase (Trx-TrxR) system		Others
T24593	PAO-PDT	PAO PDT
	PAO-PDT is a highly selective thioredoxin reductase inhibitor.
T28906	T6603185	T-6603185,T 6603185
	T6603185 is a novel inhibitor of peroxiredoxin (Prx) and thioredoxin (Trx) systems.
T70131	TPP2a bromide
	TPP2a is a mitochondrial thioredoxin reductase (TrxR) inhibitor.
T11130	DVD-445		Others
	Dvd-445 has good anti-cancer effect.Dvd-445 is an effective peptide covalent thioredoxin reductase 1 (TrxR1) inhibitor with IC50 value of 0.60 mol/L M.		Others
T34922	TRFS-red	TRFSred
	TRFS-red is the first red emission off-on probe for thioredoxin reductase.
T33413	Mito-TRFS	MitoTRFS
	Mito-TRFS is the first off-on probe for imaging the mitochondrial thioredoxin reductase (TrxR2) in live cells.
T40946	Seph-PAO
	Seph-PAO, a modified form of polyalphaolefin (PAO) compound, is created by coupling a sepharose fluorophore. Its primary application lies in the detection of thioredoxin reductase (TrxR).