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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22436 | Takeda-6d | VEGFR | |
Takeda-6d, a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor, inhibits B-RAF and VEGFR2 with IC50 of 7.0nM and 2.2nM. | |||
T24850 | Takeda103A | CMPD103A,Takeda-103A,Takeda-103-A,CMPD-103A,Takeda 103 A | GRK |
Takeda103A (CMPD103A) is the GRK2-dependent bovine tubulin oxidation effective inhibitor. | |||
T7499 | TAK-779 | Takeda 779 | HIV Protease , CXCR , CCR |
TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3). | |||
T2684 | JNJ-1661010 | JNJ1661010,Takeda-25,JNJ 1661010 | FAAH |
JNJ-1661010 (Takeda-25) is an effective and specific FAAH inhibitor (IC50: 10/ 12 nM for rat/human), shows >100-fold selectivity for FAAH-1 than FAAH-2. | |||
T8818 | TC-G 1005 | GPCR19 | |
TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and reduces blood glucose in mice. Orally available. | |||
T1530 | Mitiglinide calcium hydrate | KAD-1229 calcium hydrate,Mitiglinide calcium,S-21403 calcium hydrate | Potassium Channel |
Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes. Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) K(ATP) channels in pancreatic ... | |||
T30275 | Azilsartan trimethylethanolamine | Azilsartan,TAK-536 | |
Azilsartan is an angiotensin II receptor antagonist for the treatment of hypertension and was developed by Takeda. Azilsartan Medoxomil lowers blood pressure by blocking the effects of angiotensin II, a type of vasopress... |