Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and reduces blood glucose in mice. Orally available.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 44.00 | |
2 mg | In stock | $ 64.00 | |
5 mg | In stock | $ 105.00 | |
10 mg | In stock | $ 163.00 | |
25 mg | In stock | $ 343.00 | |
50 mg | In stock | $ 497.00 | |
100 mg | In stock | $ 742.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 116.00 |
Description | TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and reduces blood glucose in mice. Orally available. |
Targets&IC50 | TGR5 (human):0.72 nM |
Molecular Weight | 399.48 |
Formula | C25H25N3O2 |
CAS No. | 1415407-60-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (25.03 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TC-G 1005 1415407-60-1 GPCR/G Protein GPCR19 TC G 1005 G protein-coupled Bile Acid Receptor 1 levels coupled glucose TCG 1005 Takeda inhibit protein GPBAR1 TC-G1005 TC-G-1005 TGR5 Inhibitor G-protein coupled receptor 19 inhibitor