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Search Results for " tfpi "

Targets

5

Compounds

12

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T77373 Concizumab mAb 2021,NN 7415 Others
Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that selectively binds to the Kunitz protease inhibitor (KPI) 2 domain of TFPI, thereby blocking the interaction of this domain with the FXa active site. Injecti...
T81854 Marstacimab PF-06741086
Marstacimab (PF-06741086), an anti-tissue factor pathway inhibitor (TFPI) monoclonal antibody, is utilized in hemophilia research [1] [2].
T75152 ARC19499
ARC19499, an aptamer, inhibits the tissue factor pathway inhibitor (TFPI), facilitating clot initiation and propagation through the extrinsic pathway. It binds specifically to TFPI, blocking its inhibition of both factor...
T76921 Befovacimab
Befovacimab (BAY 1093884), a fully human monoclonal IgG2 antibody, binds to the tissue factor pathway inhibitor (TFPI). It is utilized in research for haemophilia A/B [1].
T38107 JJH260 JJH260
JJH260 is an N-hydroxy hydantoin carbamate that inhibits androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). It blocks the hydrolysis of 9-PAHSA with an IC50 value...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01030 TFPI Protein, Human, Recombinant (His) Human HEK293 Cells
TFPI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.6 kDa and the accession number is P10646-1.
TMPK-00194 TFPI Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and...
TMPK-00195 TFPI Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and...
TMPY-05179 TFPI Protein, Human, Recombinant (His), Biotinylated Human HEK293 Cells
TFPI Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.6 kDa and the accession number is P10646-1.
TMPY-00928 TFPI Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
TFPI Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is O54819-1.
TMPH-03211 TFPI Protein, Rabbit, Recombinant (His) Rabbit HEK293 Cells
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability t...
TMPH-03210 TFPI Protein, Rabbit, Recombinant (E. coli, His) Rabbit E. coli
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability t...
TMPY-01004 TFPI2 Protein, Human, Recombinant (His) Human HEK293 Cells
TFPI2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.2 kDa and the accession number is P48307-1.
TMPY-02329 TFPI2 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
TFPI2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.8 kDa and the accession number is O35536.
TMPY-02859 TFPI2 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
TFPI2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.4 kDa and the accession number is O35536.
TMPH-00933 ADTRP Protein, Human, Recombinant (His & Myc) Human E. coli
ADTRP Protein, Human, Recombinant (His & Myc) is expressed in in vitro E. coli expression system.
TMPY-02014 Coagulation factor VII/F7 Protein, Human, Recombinant (His) Human HEK293 Cells
Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is...
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