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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T77373 | Concizumab | mAb 2021,NN 7415 | Others |
Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that selectively binds to the Kunitz protease inhibitor (KPI) 2 domain of TFPI, thereby blocking the interaction of this domain with the FXa active site. Injecti... | |||
T81854 | Marstacimab | PF-06741086 | |
Marstacimab (PF-06741086), an anti-tissue factor pathway inhibitor (TFPI) monoclonal antibody, is utilized in hemophilia research [1] [2]. | |||
T75152 | ARC19499 | ||
ARC19499, an aptamer, inhibits the tissue factor pathway inhibitor (TFPI), facilitating clot initiation and propagation through the extrinsic pathway. It binds specifically to TFPI, blocking its inhibition of both factor... | |||
T76921 | Befovacimab | ||
Befovacimab (BAY 1093884), a fully human monoclonal IgG2 antibody, binds to the tissue factor pathway inhibitor (TFPI). It is utilized in research for haemophilia A/B [1]. | |||
T38107 | JJH260 | JJH260 | |
JJH260 is an N-hydroxy hydantoin carbamate that inhibits androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). It blocks the hydrolysis of 9-PAHSA with an IC50 value... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01030 | TFPI Protein, Human, Recombinant (His) | Human | HEK293 Cells |
TFPI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.6 kDa and the accession number is P10646-1. | |||
TMPK-00194 | TFPI Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and... | |||
TMPK-00195 | TFPI Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and... | |||
TMPY-05179 | TFPI Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
TFPI Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.6 kDa and the accession number is P10646-1. | |||
TMPY-00928 | TFPI Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
TFPI Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is O54819-1. | |||
TMPH-03211 | TFPI Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 Cells |
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability t... | |||
TMPH-03210 | TFPI Protein, Rabbit, Recombinant (E. coli, His) | Rabbit | E. coli |
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability t... | |||
TMPY-01004 | TFPI2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
TFPI2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.2 kDa and the accession number is P48307-1. | |||
TMPY-02329 | TFPI2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
TFPI2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.8 kDa and the accession number is O35536. | |||
TMPY-02859 | TFPI2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
TFPI2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.4 kDa and the accession number is O35536. | |||
TMPH-00933 | ADTRP Protein, Human, Recombinant (His & Myc) | Human | E. coli |
ADTRP Protein, Human, Recombinant (His & Myc) is expressed in in vitro E. coli expression system. | |||
TMPY-02014 | Coagulation factor VII/F7 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is... |