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Search Results for " t-type "

20

Compounds

Cat No. Product Name Synonyms Targets
T13173 TMPA Others , AMPK
TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.
T64203 T-Type calcium channel inhibitor 2
T-Type calcium channel inhibitor 2 (compound 6g) is a potent inhibitor of the T-type calcium channel, acting on Cav3.1 (α1G) (IC50: 31.0 μM), Cav3.2 (α1H) (IC50: 83.1 μM), Cav3.3 (α1I) (α1H) ( T-Type calcium channel inhi...
T8944 TTA-A2 Calcium Channel
TTA-A2 is a selective T-type calcium channel antagonist as a potent anticonvulsant that the Cav3.1 isoform plays a prominent role in mediating. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels ...
T0283 Trimethadione 3,5,5,-Trimethyloxazolidine-2,4-dione Calcium Channel
Trimethadione (3,5,5,-Trimethyloxazolidine-2,4-dione) is a dione-type anticonvulsant with antiepileptic activity.
T12032 Mibefradil dihydrochloride Ro 40-5967 (dihydrochloride) Calcium Channel
Mibefradil dihydrochloride (Ro 40-5967 (dihydrochloride)) is an blocker of calcium channel with moderate selectivity for T-type Ca2+ channels (T-type and L-type currents with IC50s of 2.7 μM and 18.6 μM, respectively).
T10024 1-Octanol Octanol Calcium Channel , Endogenous Metabolite
1-Octanol, a saturated fatty alcohol, functions as an inhibitor of T-type calcium channels (T-channels), showing an inhibitory concentration (IC50) of 4 μM for native T-currents[1]. Additionally, 1-Octanol is recognized ...
T71990 TTA-A8 Calcium Channel
TTA-A8 is an antagonist of T-type calcium channel.
T2323 Efonidipine (±)-Efonidipine,NZ-105 Calcium Channel
Efonidipine (NZ-105)(NZ-105) is a dihydropyridine calcium channel blocker, blocking both T-type and L-type calcium channels.
T5632 Suvecaltamide MK-8998 Calcium Channel
Suvecaltamide (MK-8998) as potent inhibitors of T-type calcium channels.
T3703 ABT-639 ABT 639 Calcium Channel
ABT-639 is a potent and selective T-type calcium channel blocker.
T6571 Lomerizine dihydrochloride Terranas,Lomerizine 2HCl,Lomerizine hydrochloride,KB-2796 Calcium Channel
Lomerizine dihydrochloride (KB-2796) is an antagonist of L- and T-type voltage-gated calcium channels used to treat migraine.
T12238 NNC 55-0396 NNC 55-0396 dihydrochloride Calcium Channel
NNC 55-0396 is a highly selective blocker of T-type calcium channel with IC50 of 6.8 μM. NNC 55-0396 can be used in studies about preventing human ovarian cancer cell proliferation.
T29201 Z944 Z 944,Z-944 Calcium Channel
Z944 is a T-type calcium channel blocker. Z944 delays the progression of seizures in the amygdala kindling model. Z944 disrupts prepulse inhibition in both epileptic and non-epileptic rats.
T0728 Ethosuximide Zarontin Calcium Channel
Ethosuximide (Zarontin) is an anticonvulsant, blocks the low voltage-activated T-type calcium channel used in the treatment of absence seizures unaccompanied by other types of seizures.
T8716 Physalin F Apoptosis
Physalin F is a natural blocker of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels.It is a secosteroid with potent anti-inflammatory and immunomodulatory activities. Physalin F induces apoptosis of PBM...
T8448 ZSET1446 ZSET-1446,ST-101 Calcium Channel , AChR
ZSET1446 (ST-101) is a T-type calcium channel activator potentially for the treatment of learning deficits in various types of Alzheimer disease (AD) models.
T64387 2-Nitrobenzoic acid o-Nitrobenzoic acid Others
2-Nitrobenzoic acid (o-Nitrobenzoic acid) is a antiproliferation agent. 2-Nitrobenzoic acid shows IC50 of 8.3 μM to jurkat cell line expressing T type calcium channel alpha 1H or its splice variant delta 25.
T23411L T-0156 T 0156 PDE , Parasite
T-0156 is a novel, potent and selective phosphodiesterase type 5 inhibitor that inhibits the hydrolysis of cyclic guanosine monophosphate (cGMP) with low affinity for PDE6, PDE1, PDE2, PDE3 and PDE4.
T37427 (2R/S)-6-PNG 6-Prenylnaringenin,(±)-6-Prenylnaringenin Calcium Channel , HDAC
(2R/S)-6-PNG (6-Prenylnaringenin) is a novel natural histone deacetylase inhibitor with anticancer and antitumor activity, and blocks T-type calcium channels to reduce neuropathic and visceral pain in mice.
T68123 Oxodipine Calcium Channel
Oxodipine, a dihydropyridine-type calcium antagonist , inhibited KCl-induced aortic contraction in rabbits and reduced cardiac force in less potent rat ventricular test-paper contractions. In rat cultured neonatal ventri...
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