20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13173 | TMPA | Others , AMPK | |
TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist. | |||
T64203 | T-Type calcium channel inhibitor 2 | ||
T-Type calcium channel inhibitor 2 (compound 6g) is a potent inhibitor of the T-type calcium channel, acting on Cav3.1 (α1G) (IC50: 31.0 μM), Cav3.2 (α1H) (IC50: 83.1 μM), Cav3.3 (α1I) (α1H) ( T-Type calcium channel inhi... | |||
T8944 | TTA-A2 | Calcium Channel | |
TTA-A2 is a selective T-type calcium channel antagonist as a potent anticonvulsant that the Cav3.1 isoform plays a prominent role in mediating. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels ... | |||
T0283 | Trimethadione | 3,5,5,-Trimethyloxazolidine-2,4-dione | Calcium Channel |
Trimethadione (3,5,5,-Trimethyloxazolidine-2,4-dione) is a dione-type anticonvulsant with antiepileptic activity. | |||
T12032 | Mibefradil dihydrochloride | Ro 40-5967 (dihydrochloride) | Calcium Channel |
Mibefradil dihydrochloride (Ro 40-5967 (dihydrochloride)) is an blocker of calcium channel with moderate selectivity for T-type Ca2+ channels (T-type and L-type currents with IC50s of 2.7 μM and 18.6 μM, respectively). | |||
T10024 | 1-Octanol | Octanol | Calcium Channel , Endogenous Metabolite |
1-Octanol, a saturated fatty alcohol, functions as an inhibitor of T-type calcium channels (T-channels), showing an inhibitory concentration (IC50) of 4 μM for native T-currents[1]. Additionally, 1-Octanol is recognized ... | |||
T71990 | TTA-A8 | Calcium Channel | |
TTA-A8 is an antagonist of T-type calcium channel. | |||
T2323 | Efonidipine | (±)-Efonidipine,NZ-105 | Calcium Channel |
Efonidipine (NZ-105)(NZ-105) is a dihydropyridine calcium channel blocker, blocking both T-type and L-type calcium channels. | |||
T5632 | Suvecaltamide | MK-8998 | Calcium Channel |
Suvecaltamide (MK-8998) as potent inhibitors of T-type calcium channels. | |||
T3703 | ABT-639 | ABT 639 | Calcium Channel |
ABT-639 is a potent and selective T-type calcium channel blocker. | |||
T6571 | Lomerizine dihydrochloride | Terranas,Lomerizine 2HCl,Lomerizine hydrochloride,KB-2796 | Calcium Channel |
Lomerizine dihydrochloride (KB-2796) is an antagonist of L- and T-type voltage-gated calcium channels used to treat migraine. | |||
T12238 | NNC 55-0396 | NNC 55-0396 dihydrochloride | Calcium Channel |
NNC 55-0396 is a highly selective blocker of T-type calcium channel with IC50 of 6.8 μM. NNC 55-0396 can be used in studies about preventing human ovarian cancer cell proliferation. | |||
T29201 | Z944 | Z 944,Z-944 | Calcium Channel |
Z944 is a T-type calcium channel blocker. Z944 delays the progression of seizures in the amygdala kindling model. Z944 disrupts prepulse inhibition in both epileptic and non-epileptic rats. | |||
T0728 | Ethosuximide | Zarontin | Calcium Channel |
Ethosuximide (Zarontin) is an anticonvulsant, blocks the low voltage-activated T-type calcium channel used in the treatment of absence seizures unaccompanied by other types of seizures. | |||
T8716 | Physalin F | Apoptosis | |
Physalin F is a natural blocker of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels.It is a secosteroid with potent anti-inflammatory and immunomodulatory activities. Physalin F induces apoptosis of PBM... | |||
T8448 | ZSET1446 | ZSET-1446,ST-101 | Calcium Channel , AChR |
ZSET1446 (ST-101) is a T-type calcium channel activator potentially for the treatment of learning deficits in various types of Alzheimer disease (AD) models. | |||
T64387 | 2-Nitrobenzoic acid | o-Nitrobenzoic acid | Others |
2-Nitrobenzoic acid (o-Nitrobenzoic acid) is a antiproliferation agent. 2-Nitrobenzoic acid shows IC50 of 8.3 μM to jurkat cell line expressing T type calcium channel alpha 1H or its splice variant delta 25. | |||
T23411L | T-0156 | T 0156 | PDE , Parasite |
T-0156 is a novel, potent and selective phosphodiesterase type 5 inhibitor that inhibits the hydrolysis of cyclic guanosine monophosphate (cGMP) with low affinity for PDE6, PDE1, PDE2, PDE3 and PDE4. | |||
T37427 | (2R/S)-6-PNG | 6-Prenylnaringenin,(±)-6-Prenylnaringenin | Calcium Channel , HDAC |
(2R/S)-6-PNG (6-Prenylnaringenin) is a novel natural histone deacetylase inhibitor with anticancer and antitumor activity, and blocks T-type calcium channels to reduce neuropathic and visceral pain in mice. | |||
T68123 | Oxodipine | Calcium Channel | |
Oxodipine, a dihydropyridine-type calcium antagonist , inhibited KCl-induced aortic contraction in rabbits and reduced cardiac force in less potent rat ventricular test-paper contractions. In rat cultured neonatal ventri... |