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Search Results for " t-47d "

9

Compounds

Cat No. Product Name Synonyms Targets
TN1768 Iriflophenone Estrogen Receptor/ERR , Estrogen/progestogen Receptor
Iriflophenone stimulates cells proliferation in  MCF-7 and T-47D human breast cancer.
T0272 Nilutamide RU23908 Androgen Receptor
Nilutamide (RU23908), an antineoplastic hormonal agent, is mainly used in the treatment of prostate Y. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors, but not for estrogen, progesto...
T3521 γ-Secretase-IN-1 Compound E Beta Amyloid , Gamma-secretase
γ-Secretase-IN-1 is a potent γ-secretase inhibitor that displays partial antiproliferative activity on T-47D cells and inhibits β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage.
TN4455 Lucialdehyde B Integrase , HSV
Lucialdehyde B exhibits potent inhibitory activity against herpes simplex virus. It shows cytotoxic effects on Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, and Meth-A tumor cell lines.
T36860 C22 Sphingomyelin (d18:1/22:0) C22 Sphingomyelin (d18:1/22:0)
C22 Sphingomyelin is a naturally occurring form of sphingomyelin . Plasma levels of C22 sphingomyelin positively correlate with hepatic steatosis severity in patients with chronic hepatitis C virus (HCV). C22 Sphingomyel...
TN4457 Lucidal Others
Lucialdehyde C (Lucidal) exhibits potent cytotoxicity against LLC, T-47D, Sarcoma 180, and Meth-A tumor cells with ED(50) values of 10.7, 4.7, 7.1, and 3.8 microg/ml, respectively.
T61686 Steroid sulfatase-IN-3
Steroid sulfatase-IN-3 (compound 1q) is a highly effective Steroid sulfatase (STS) inhibitor, exhibiting an IC 50 value of 25.8 nM. This compound also demonstrates antiproliferative properties against T-47D estrogen-depe...
T81091 Steroid sulfatase-IN-5
Steroid sulfatase-IN-5 (compound 10b), an inhibitor of steroid sulfatase (STS) with an IC50 of 0.32 nM, effectively suppresses T-47D breast cancer cell proliferation, demonstrating an IC50 value of 35.7 μM. This compound...
T14144 AGN-195183 Others
AGN 195183 is a potent and selective agonist of RARα(Kd=3 nM) with improved binding selectivity relative to AGN 193836; no activity on RARβ/γ. IC50 value: 3 nM (Kd); 200 nM (EC80, RAR Trans.) Target: RARα agonist Compoun...
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