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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN1768 | Iriflophenone | Estrogen Receptor/ERR , Estrogen/progestogen Receptor | |
Iriflophenone stimulates cells proliferation in MCF-7 and T-47D human breast cancer. | |||
T0272 | Nilutamide | RU23908 | Androgen Receptor |
Nilutamide (RU23908), an antineoplastic hormonal agent, is mainly used in the treatment of prostate Y. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors, but not for estrogen, progesto... | |||
T3521 | γ-Secretase-IN-1 | Compound E | Beta Amyloid , Gamma-secretase |
γ-Secretase-IN-1 is a potent γ-secretase inhibitor that displays partial antiproliferative activity on T-47D cells and inhibits β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage. | |||
TN4455 | Lucialdehyde B | Integrase , HSV | |
Lucialdehyde B exhibits potent inhibitory activity against herpes simplex virus. It shows cytotoxic effects on Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, and Meth-A tumor cell lines. | |||
T36860 | C22 Sphingomyelin (d18:1/22:0) | C22 Sphingomyelin (d18:1/22:0) | |
C22 Sphingomyelin is a naturally occurring form of sphingomyelin . Plasma levels of C22 sphingomyelin positively correlate with hepatic steatosis severity in patients with chronic hepatitis C virus (HCV). C22 Sphingomyel... | |||
TN4457 | Lucidal | Others | |
Lucialdehyde C (Lucidal) exhibits potent cytotoxicity against LLC, T-47D, Sarcoma 180, and Meth-A tumor cells with ED(50) values of 10.7, 4.7, 7.1, and 3.8 microg/ml, respectively. | |||
T61686 | Steroid sulfatase-IN-3 | ||
Steroid sulfatase-IN-3 (compound 1q) is a highly effective Steroid sulfatase (STS) inhibitor, exhibiting an IC 50 value of 25.8 nM. This compound also demonstrates antiproliferative properties against T-47D estrogen-depe... | |||
T81091 | Steroid sulfatase-IN-5 | ||
Steroid sulfatase-IN-5 (compound 10b), an inhibitor of steroid sulfatase (STS) with an IC50 of 0.32 nM, effectively suppresses T-47D breast cancer cell proliferation, demonstrating an IC50 value of 35.7 μM. This compound... | |||
T14144 | AGN-195183 | Others | |
AGN 195183 is a potent and selective agonist of RARα(Kd=3 nM) with improved binding selectivity relative to AGN 193836; no activity on RARβ/γ. IC50 value: 3 nM (Kd); 200 nM (EC80, RAR Trans.) Target: RARα agonist Compoun... |