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Search Results for " sum149 "

5

Compounds

Cat No. Product Name Synonyms Targets
T22089 HPI 1 Hedgehog/Smoothened
HPI 1 is a hedgehog (Hh) signaling inhibitor. Inhibits Sonic hedgehog (Shh)-, SAG- and Gli-induced Hh pathway activation in Shh-LIGHT2 cells (IC50 values are 1.5, 1.5, 4, and 6 μM for Shh-, SAG-, Gli2- and Gli1-induced a...
T72968 ZINC00640089 Akt
ZINC00640089 is a selective lipid carrier protein-2 (LCN2) inhibitor. ZINC00640089 inhibited cell proliferation and cell viability, and reduced AKT phosphorylation in SUM149 cells. ZINC00640089 can be used to study infla...
T6982 SGI-7079 FLT , c-Met/HGFR , c-RET , TAM Receptor , Src
SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors. It is also a potential therapeutic target for EGFR inhibitor resistance.
T78149 ZINC00784494 Others
ZINC00784494, a specific Lipocalin-2 (LCN2) inhibitor, impedes cell proliferation and viability while diminishing AKT phosphorylation in SUM149 cells, showing promise for research on inflammatory breast cancer (IBC) [1].
T6120 Pralatrexate Folotyn,10-Propargyl-10-deazaaminopterin Apoptosis , DHFR , Antifolate , TAM Receptor
Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive act...
TargetMol