sn — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1703	SN-38	NK012,SN 38	DNA/RNA Synthesis , Topoisomerase , Autophagy
	SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, which inhibits DNA and RNA synthesis (IC50=0.077/1.3 μM). SN-38 has antitumor activity and induces autophagy.		DNA/RNA Synthesis , Topoisomerase , Autophagy
T19343	sn-Glycerol 3-phosphate	Glycerol 3-phosphate,sn-Glycerol 3-phosphate lithium salt	Endogenous Metabolite
	sn-Glycerol 3-phosphate is produced by the reduction of dihydroxyacetone phosphate by NADH formed during glycolysis of the cytoplasmic glycerol 3-phosphate dehydrogenase pathway.		Endogenous Metabolite
T9554	SN-008		STING
	SN-008 is a less active analog SN-011 which is a STING antagonist. SN-008 can be used as a negative control.		STING
T12941	SN 2		TRP/TRPV Channel
	SN 2 is a novel and potent TRPML3 ion channel activator(EC50 of 1.8±0.13 μM).		TRP/TRPV Channel
T9204	SN-001		STING
	SN-001 was reported as a STING inhbiitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING- mediated disease.		STING
T5457	SN 6	SN6	Calcium Channel , Na+/Ca2+ Exchanger
	SN 6 (SN6) is a selective Na+/Ca2+ exchanger (NCX) inhibitor (IC50s of NCX1: 2.9 μM , NCX2: 16 μM ,NCX3: 8.6 μM)		Calcium Channel , Na+/Ca2+ Exchanger
T8712	1-Palmitoyl-sn-glycero-3-phosphocholine	1-Hexadecanoyl-sn-glycero-3-phosphocholine	Others
	1-Palmitoyl-sn-glycero-3-phosphocholine (1-Hexadecanoyl-sn-glycero-3-phosphocholine) is a phosphocholine for fluorescent probe design		Others
T5238	1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine	1,2-Dipalmitoyl-sn-glycero-3-PE,1,2-Dipalmitoyl-sn-glycerol-3-Phosphoethanolamine,1,2-DPPE	Others , Endogenous Metabolite
	1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE), a phospholipid member of the glycerophosphonoethanolamine family, is a major component in biological membranes. Studies focused on interactions between DPPE and ch...		Others , Endogenous Metabolite
T5249	1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine	1,2-DSPE,1,2-Distearoyl-sn-glycero-3-phosphoethan	Others , Endogenous Metabolite
	1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (1,2-DSPE) is a phosphatidylethanolamine (PE or GPEtn). The stearic acid moieties are derived from animal fats, coco butter, and sesame oil. Phospholipids, are ubiquitou...		Others , Endogenous Metabolite
T9525	1,2-Dimyristoyl-sn-glycero-3-phosphocholine	DMPC,1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOL	Others
	1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) (DMPC) is a synthetic phospholipid used in liposomes which is used for the study of lipid monolayers and bilayers[1].		Others
T35606	1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium	1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)
	1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)) can be used in lipid mixtures with DOPC and DOPE as effective nontoxic and nonviral DNA vectors. 1,2-Dioleoyl-sn-glycero-3-ph...
T9137	SN-011	[1,1'-Biphenyl]-4-carboxamide, N-[3-[[(4-fluorophenyl)sulfonyl]amino]-4-hydroxyphenyl]-,GUN35901	STING
	SN-011 (GUN35901) is a STING inhibitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING- mediated disease. It is a demethyl analogue of DUN99845.		STING
T22463	1,2-Dilauroyl-sn-glycerol	1,2-DLG,(S)-1,2-Dilaurin	Others
	1,2-Dilauroyl-sn-glycerol ((S)-1,2-Dilaurin) is primarily composed of the interaction of 1,2-dilauroyl-sn-glycerol (1,2-DLG) with phosphatidylcholine (PC) bilayers.		Others
T9510	1,2-Distearoyl-sn-glycero-3-phosphorylcholine	DSPC,L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL,1,2-Distearoyl-sn-glycero-3-PC	Others
	1,2-Distearoyl-sn-glycero-3-phosphorylcholine (L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL) is a cylindrical-shaped lipid used to synthesize liposomes. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (L-ALPHA-PHOSPHATIDYLCHOLI...		Others
T19085	1-Palmitoyl-2-oleoyl-sn-glycero-3-PC	POPC,1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine,Palmitoyloleoylphosphatidylcholine	Others
	1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Palmitoyloleoylphosphatidylcholine) is a phospholipid ubiquitous in cell membranes, with compositions in the range 0-60 mol% cholesterol.		Others
T22465	1,2-Distearoyl-sn-glycerol		Others
	1,2-Distearoyl-sn-glycerol is an internal standard for the isolation and characterization of molecular species of 1,2-diacyl-sn-glycerol (DAG).		Others
T8713	1-Oleoyl-sn-glycero-3-phosphocholine		Others
	1-Oleoyl-sn-glycero-3-phosphocholine is a reference for the analysis of lysolecithins		Others
T4950	1,2-Dipalmitoyl-sn-glycerol	(S)-1,2-Dipalmitin	Endogenous Metabolite , PKC
	1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.		Endogenous Metabolite , PKC
T17731L	CL2A-SN-38 DCA 1279680-68-0(free base)		Others
	CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC).. CL2A-SN-38 is composed of a potent a DNA Topoisomerase I inhibito...		Others
T22464	1,2-Dimyristoyl-sn-glycerol	1,2-DMG	Others , PKC
	1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is able to increase AChE activity by 35-40% at concentrations of 25 micrograms/ml in the parasite S. mansoni..		Others , PKC