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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10379 | Arzoxifene hydrochloride | SERM 3,LY 353381 HCl | Others |
Arzoxifene hydrochloride is a selective estrogen receptor modulator that is a potent estrogen antagonist in mammary and uterine tissue. | |||
T2544 | Bazedoxifene acetate | WAY-TES 424,TSE 424,WAY-140424 | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Bazedoxifene acetate (WAY-TES 424) is a novel selective estrogen receptor modulator (SERM). | |||
T6404 | Bazedoxifene hydrochloride | Bazedoxifene HCl,TSE-424 | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Bazedoxifene hydrochloride (TSE-424) is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM, respectively. | |||
T73702 | Mecasermin | ||
Mecasermin (Human IGF-I; FK 780), a recombinant form of human insulin-like growth factor I (IGF-I), holds promise for investigating growth failure attributed to growth hormone (GH) insensitivity, which may be due to defe... | |||
T24002 | Disermolide | XAA 296,XAA296,XAA-296 | |
Disermolide is a polyketide natural product found to stabilize microtubules. Disermolide was found to be a potent inhibitor of tumor cell growth in several MDR cancer cell lines. | |||
T26186 | Sermetacin | Sermetacina,SH G 318 AB,SHG 318 AB,TVX 3158 | |
Sermetacin is an anti-inflammatory agent. | |||
T25534 | Indazole-Cl | Indazole Cl | Estrogen/progestogen Receptor |
Indazole-Cl is a selective ERß agonist and a selective estrogen receptor modifier (SERM). | |||
T27322 | Fispemifene | HM-101,HM 101,HM101 | Others |
Fispemifene (HM-101) is an estrogen receptor modulator (SERM) used to treat genitourinary syndromes and vaginal atrophy. | |||
T4420 | 4-Hydroxytamoxifen | ICI 79280,(Z)-4-hydroxy Tamoxifen,trans-4-Hydroxytamoxifen | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
4-Hydroxytamoxifen (ICI 79280) is the active metabolite of Tamoxifen, an estrogen receptor modulator (SERM) with selective and oral potency. 4-Hydroxytamoxifen has antitumor activity and may be used in breast cancer rese... | |||
T15249 | Estrogen receptor modulator 1 | Estrogen Receptor/ERR | |
Estrogen receptor modulator 1 causes regression of Tamoxifen-resistant, hormone-independent xenograft tumors. Estrogen receptor modulator 1 is an orally active and selective estrogen receptor modulator (SERM) (pIC50: 0.4... | |||
T1549 | Raloxifene hydrochloride | LY156758 hydrochloride,Raloxifene HCl,LY139481 hydrochloride,Keoxifene hydrochloride,LY156758 (Keoxifene) HCl | Estrogen Receptor/ERR , Others , MAO , Estrogen/progestogen Receptor , Autophagy |
Raloxifene hydrochloride (LY156758 hydrochloride) is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and chol... | |||
T2569 | Chlorotrianisene | tris(p-methoxyphenyl)chloroethylene,CTA,tri-p-anisylchloroethylene,TACE | Estrogen Receptor/ERR , Estrogen/progestogen Receptor , COX |
Chlorotrianisene (tri-p-anisylchloroethylene) is an orally bioavailable, highly lipophilic, synthetic triphenylethylene (TPE) derivative and selective estrogen receptor modulator (SERM), with predominantly estrogenic but... | |||
T6620 | Ospemifene | FC-1271a | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Ospemifene (FC-1271a) is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. FDA ap... | |||
T7839 | Lasofoxifene Tartrate | CP-336156 | Estrogen Receptor/ERR |
Lasofoxifene Tartrate (CP-336156) is a third-generation, non-steroidal selective estrogen receptor modulator. | |||
T28957 | TFR4OHT | TFR-4-OHT,TFR 4 OHT | |
TFR4OHT is a selective ER modulator (SERM). | |||
T25700L | Levormeloxifene fumarate | ||
Levormeloxifene fumarate is an osteoporosis drug and selective estrogen receptor modulator (SERM). | |||
T3645 | Endoxifen E-isomer hydrochloride | E-Endoxifen hydrochloride | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Endoxifen E-isomer hydrochloride (E-Endoxifen hydrochloride) , a tamoxifen metabolite, is effective specific Estrogen Response Modifier (SERM). | |||
T27946 | LY-329146 | LY 329146 | |
LY-329146 is a selective estrogen receptor modulator (SERM). LY-329146 prevents doxorubicin resistance in tumor cells expressing multidrug resistance-associated protein (MRP) by inhibiting the binding of MRP substrates t... | |||
T13076 | Tamoxifen-d5 | ICI 47699-d5,(Z)-Tamoxifen-d5,trans-Tamoxifen-d5 | HSP |
Tamoxifen-d5 is a deuterium labeled Tamoxifen. Tamoxifen is a selective modulator of estrogen receptor (SERM). Tamoxifen is a potent activator of Hsp90 and enhances the Hsp90 molecular chaperone ATPase activity. | |||
T62119 | Lasofoxifene | ||
Lasofoxifene (CP-336156) is a selective, orally active estrogen receptor modulator (SERM) that inhibits the growth and metastasis of primary tumours and is also anti-osteoporotic. |