20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7695 | PNU-282987 S enantiomer free base | AChR | |
PNU-282987 S enantiomer free base is an agonist of α7 nicotinic acetylcholine receptor (α7 nAChR). | |||
T10819 | Cipropride S enantiomer | Others | |
Cipropride S enantiomer is the S enantiomer of cipropride which is an antiemetic drug. | |||
T17102 | Tipifarnib (S enantiomer) | Tipifarnib S enantiomer,(S)-(-)-R-115777,(S)-Tipifarnib,IND-58359 S enantiomer | Transferase |
Tipifarnib S enantiomer ((S)-(-)-R-115777) is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase inhibitor (IC50: 0.6 nM). | |||
T7058 | Selisistat S-enantiomer | EX-527 S-enantiomer,EX-527 (S-enantiomer) | Sirtuin |
Selisistat S-enantiomer (EX-527 S-enantiomer) is an effective and specific SIRT1 inhibitor (IC50 = 98 nM) and shows >200-fold selectivity against SIRT2/3. | |||
T80678 | (S)-AK-242 | (-)-Resatorvid,(S)-Resatorvid,AK-242 (S enantiomer),(-)-AK-242 | Others |
(S)-AK-242 ((S)-Resatorvid) is a cytokine inhibitor used in the treatment of heart disease, autoimmune disease, and inflammatory disease. | |||
T6156 | Ruxolitinib (S enantiomer) | S-Ruxolitinib,Ruxolitinib S enantiomer,INCB018424,INCB18424 | Tyrosine Kinases , JAK |
Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor. | |||
T11391 | Gepotidacin S enantiomer | GSK2140944 S enantiomer | Others |
Gepotidacin S enantiomer is an S enantionmer of gepotidacin. | |||
T11173 | Elacestrant S enantiomer | RAD1901 S enantiomer | Others |
Elacestrant S enantiomer is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively. | |||
T11335 | Fulvestrant (S enantiomer) | ZM 182780 S enantiomer,ICI 182780 S enantiomer,Fulvestrant S enantiomer,ZD 9238 S enantiomer | Others |
Fulvestrant S enantiomer is the less active S enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM. | |||
T10465 | Atuveciclib S-Enantiomer | BAY-1143572 S-Enantiomer | CDK |
Atuveciclib S-Enantiomer (BAY-1143572 S-Enantiomer) is the (S)-enantiomer of BAY-1143572. Atuveciclib S-Enantiomer is a potent and selective CDK9 inhibitor, which inhibits CDK9 / CycT1 with an IC 50 of 16 nM. | |||
T12200 | Firsocostat S enantiomer | ND-630 S enantiomer,NDI-010976 S enantiomer,GS-0976 S enantiomer | Others |
Firsocostat S enantiomer is the less active S enantiomer of Firsocostat. | |||
T11156 | Nazartinib S-enantiomer | EGF816 (S-enantiomer) | Others |
Nazartinib is an EGFR inhibitor. Nazartinib S-enantiomer is the less active S-enantiomer of Nazartinib. | |||
T22401 | PNU-282987 S enantiomer hydrochloride | (S)-PNU-282987 HCl | Others |
(S)-PNU-282987 is the absolute stereochemistry form of PNU-282987. PNU 282987, a potent agonist of α7-containing neuronal nicotinic acetylcholine receptors (nAChRs) with Ki of 26 nM for the rat receptor, has negligible a... | |||
T11628 | IACS-8968 S-enantiomer | IDO/TDO Inhibitor (S-enantiomer) | IDO |
IACS-8968 S-enantiomer is the S-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO). | |||
T11173L | Elacestrant S enantiomer dihydrochloride | RAD1901 S enantiomer dihydrochloride,RAD-1901 S enantiomer dihydrochloride,RAD 1901 S enantiomer dihydrochloride | Others |
Elacestrant (RAD1901) dihydrochloride is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant S enantiomer dihydrochloride is an l... | |||
T12203 | Necrostatin 2 S enantiomer | Others | |
Necrostatin 2 S enantiomer is the S enantiomer of Necrostatin 2 | |||
T12067 | MK-7246 S enantiomer | Others | |
MK-7246 S enantiomer is a potent and selective CRTH2 antagonist. | |||
T11378 | GDC-0834 S-enantiomer | Others | |
GDC-0834, the S-enantiomer, is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK). | |||
T11902 | LY 344864 S-enantiomer | Others | |
LY 344864 S-enantiomer, the S-enantiomer of LY344864, serves as a 5-HT1F receptor agonist. | |||
T9848 | GSK2850163 (S enantiomer) | IRE1 | |
GSK2850163 (S enantiomer) is the inactive enantiomer of GSK2850163. GSK2850163 is an novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1a). |