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Compounds

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Recombinant Proteins

Cat No. Product Name Synonyms Targets
T71029 RCC-36 HCl
Rcc 36 is an active metabolite of temiverine that has inhibitory actions toward the atropine-resistant part of contractions, which may be related to the calcium antagonistic actions of these compounds.
T26046 Razoxane Topoisomerase
Razoxane is used as an antimitotic agent with immunosuppressive properties.
T6683 STF-62247 STF 62247 Estrogen/progestogen Receptor , Autophagy
STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively.
T9698 UC2288 Mdm2 , p53
UC2288 is a relatively selective p21 attenuator which is synthesized based Sorafenib. UC2288 attenuates p21 protein levels with minimal effect on p21 protein stability.
T71027 KDI-792 hydrochloride
KDI-792 hydrochloride is a thromboxane dual blocker.
T60904 ERCC1-XPF-IN-2 Others
ERCC1-XPF-IN-2 is active in nucleotide excision repair, cisplatin enhancement and γH2AX assays. ERCC1-XPF-IN-2 is a potent inhibitor of ERCC1-XPF endonuclease with an IC 50 value of 0.6 μM [1].
T63464 ERCC1-XPF-IN-1
ERCC1-XPF-IN-1 is a potent, high-affinity inhibitor of ERCC1-XPF (IC50: 0.49 μM). ERCC1-XPF-IN-1 inhibits the removal of CPDs, reduces the toxicity of cyclophosphamide to colorectal cancer cells, enhances the cytotoxic e...
T14318 ARCC-4 Others
ARCC-4 is an enzalutamide-based von Hippel-Lindau (VHL)-recruiting AR PROTAC and outperforms enzalutamide and it is a low-nanomolar androgen receptor (AR) degrader based on PROTAC, with a DC50 of 5 nM. ARCC-4 effectively...
T41227 ARCC 4 negative control
ARCC 4 negative control is a negative control for ARCC 4. Binds androgen receptors (AR) without inducing degradation.
T63505 Tivozanib hydrochloride hydrate
Tivozanib hydrochloride hydrate is a selective, potent, orally active VEGFR tyrosine kinase inhibitor that acts on VEGFR-1 (IC50: 0.21 nM), VEGFR-2 (IC50: 0.16 nM), and VEGFR-3 (IC50: 0.24 nM). Tivozanib hydrochloride hy...
T76723 Tilvestamab
Tilvestamab (BGB149), a humanized anti-AXL antibody, effectively blocks AXL-mediated cell signaling, significantly reduces Gas6-induced AXL activation, and inhibits downstream AKT phosphorylation in 786-0-Luc RCC cells. ...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00283 Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated Human HEK293 Cells
Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzym...
TMPK-00283 CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tu...
TMPK-00524 CA9/Carbonic Anhydrase IX Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tu...
TMPK-00478 Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues. Carbonic anhydrase XII (CA XII) is a key mediator of several signaling pathways that are involved in ...
TMPH-01380 ERCC3 Protein, Human, Recombinant (GST) Human E. coli
ERCC3 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 115.6 kDa and the accession number is P19447.
TMPH-02314 XRCC5 Protein, Human, Recombinant (His & MBP) Human Baculovirus Insect Cells
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a...
TMPH-02159 SMARCC1 Protein, Human, Recombinant (His & SUMO) Human E. coli
SMARCC1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 41.5 kDa and the accession number is Q92922.
TMPH-01621 BRCC3 Protein, Human, Recombinant (His & SUMO) Human E. coli
Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not have activity toward 'Lys-48'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes...
TMPH-02315 XRCC5 Protein, Human, Recombinant (His & Myc) Human E. coli
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a...
TMPY-01763 Cadherin 16/CDH16 Protein, Human, Recombinant (His) Human HEK293 Cells
KSP-Cadherin/Cadherin-16 is a member of the cadherin superfamily, calcium-dependent, membrane-associated glycoproteins. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane regio...
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