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Search Results for " pgd "

Targets

14

Compounds

1

Natural Products

8

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T4624 PGD2-IN-1 PGD2-inhibitor Prostaglandin Receptor
PGD2-IN-1 (PGD2-inhibitor) is an effective DP receptor antagonist (IC50:0.3 nM), a compound that can inhibit prostaglandin D2 (PGD2) signaling. PGD2-IN-1 specifically targets and regulates the activity of PGD2 receptors ...
T1804 HPGDS inhibitor 1 HPGDS-inhibitor-1 PGE Synthase
HPGDS inhibitor 1 is a novel and selective inhibitor for Hematopoietic Prostaglandin D Synthase (HPGDS) with an IC50 Value of 0.7 nM.
T26397 6PGD-IN-S3 6PGD Inhibitor S3,S3,Danthron methyl derivative Dehydrogenase
6PGD-IN-S3 (6PGD Inhibitor S3) is an inhibitor of 6-phosphogluconate dehydrogenase (6PGD).
T2681 HPGDS-IN-1 PGE Synthase
hPGDS-IN-1 is a hPGDS inhibitor.
T7948 HPGDS inhibitor 2 GSK-2894631A PGE Synthase
HPGDS inhibitor 2 (GSK-2894631A) is a potent, selective hematopoietic prostaglandin D synthase (h-pgds) inhibitor, IC50 = 9.9 nm.
T38306 Tetranor-PGDM
Prostaglandin D2 is synthesized by hematopoietic-type PGD-synthase (H-PGDS) in mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. PGD2 is also produced in the brain by lipocalin-PGD...
T38257 PGDM
Prostaglandin D2 (PGD2) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smoot...
T61250 HPGDS inhibitor 3
HPGDS inhibitor 3 is a powerful oral compound that selectively inhibits the hematopoietic prostaglandin D synthase (H-PGDS). With an IC50 value of 9.4 nM and EC50 of 42 nM, it demonstrates high potency in peripherally re...
T72950 15-PGDH-IN-1
15-PGDH-IN-1 is an orally active, potent inhibitor of 15-PGDH, exhibiting significant inhibitory activity against recombinant human 15-PGDH with an IC50 value of 3 nM. This compound is utilized in the research of tissue ...
T41267 PROTAC(H-PGDS)-7
PROTAC(H-PGDS)-7 is a selective and potent small molecule hematopoietic prostaglandin D synthase (H-PGDS) PROTAC degradation agent that exhibits degradation activity in KU812 cells with a DC50 of 17.3 pM. PROTAC(H-PGDS)-...
T73336 Ketotifen HC 20-511
Ketotifen (HC 20-511) is a second-generation, orally active noncompetitive histamine 1 (H1) receptor antagonist and mast cell stabilizer. It inhibits 6-phosphogluconate dehydrogenase (PGD) in vitro and displays antiviral...
T36545 Prostaglandin D2 methyl ester Prostaglandin D2 methyl ester
Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis. It causes vasodilation, flushing, hypoten...
T71088 AM-211 sodium
AM-211 sodium is a novel and potent antagonist of the prostaglandin D2 receptor type 2. AM-211 is active in animal models of allergic inflammation. AM211 has high affinity for human, mouse, rat, and guinea pig DP2 and it...
T38389 Prostaglandin D2 Ethanolamide Prostaglandin D2 Ethanolamide
Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential metabolism of anandamide (arachidonoyl ethanolamide) by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase. The ...
Cat No. Product Name Synonyms Targets
T13831 Prostaglandin D2 PGD2 Endogenous Metabolite
Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals,and is a potent endogenous sleep promoting substances.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02801 PHGDH Protein, Human, Recombinant (His) Human E. coli
PHGDH is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family. This new family consists of D-isomer-stereospecific enzymes. The conserved residues in this family appear to be the residues involved in the ...
TMPY-02422 PGD Protein, Human, Recombinant (His) Human E. coli
PGD Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 54.6 kDa and the accession number is P52209.
TMPY-03120 Prostaglandin D2 Synthase Protein, Human, Recombinant (His) Human HEK293 Cells
Prostaglandin D2 Synthase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.1 kDa and the accession number is P41222.
TMPJ-00690 PGDS Protein, Human, Recombinant Human E. coli
Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macroph...
TMPY-04077 HPGDS/PGD2 Protein, Human, Recombinant (His) Human E. coli
HPGDS/PGD2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.2 kDa and the accession number is O60760.
TMPY-04624 Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.9 kDa and the accession number is O09114-1.
TMPY-02273 15-PGDH Protein, Mouse, Recombinant (His) Mouse E. coli
15-PGDH Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30.6 kDa and the accession number is Q8VCC1.
TMPY-01264 15-PGDH Protein, Human, Recombinant (His) Human E. coli
15-PGDH Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 29.7 kDa and the accession number is P15428-1.
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