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Cat No. | Product Name | Synonyms | Targets |
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T4624 | PGD2-IN-1 | PGD2-inhibitor | Prostaglandin Receptor |
PGD2-IN-1 (PGD2-inhibitor) is an effective DP receptor antagonist (IC50:0.3 nM), a compound that can inhibit prostaglandin D2 (PGD2) signaling. PGD2-IN-1 specifically targets and regulates the activity of PGD2 receptors ... | |||
T1804 | HPGDS inhibitor 1 | HPGDS-inhibitor-1 | PGE Synthase |
HPGDS inhibitor 1 is a novel and selective inhibitor for Hematopoietic Prostaglandin D Synthase (HPGDS) with an IC50 Value of 0.7 nM. | |||
T26397 | 6PGD-IN-S3 | 6PGD Inhibitor S3,S3,Danthron methyl derivative | Dehydrogenase |
6PGD-IN-S3 (6PGD Inhibitor S3) is an inhibitor of 6-phosphogluconate dehydrogenase (6PGD). | |||
T2681 | HPGDS-IN-1 | PGE Synthase | |
hPGDS-IN-1 is a hPGDS inhibitor. | |||
T7948 | HPGDS inhibitor 2 | GSK-2894631A | PGE Synthase |
HPGDS inhibitor 2 (GSK-2894631A) is a potent, selective hematopoietic prostaglandin D synthase (h-pgds) inhibitor, IC50 = 9.9 nm. | |||
T38306 | Tetranor-PGDM | ||
Prostaglandin D2 is synthesized by hematopoietic-type PGD-synthase (H-PGDS) in mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. PGD2 is also produced in the brain by lipocalin-PGD... | |||
T38257 | PGDM | ||
Prostaglandin D2 (PGD2) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smoot... | |||
T61250 | HPGDS inhibitor 3 | ||
HPGDS inhibitor 3 is a powerful oral compound that selectively inhibits the hematopoietic prostaglandin D synthase (H-PGDS). With an IC50 value of 9.4 nM and EC50 of 42 nM, it demonstrates high potency in peripherally re... | |||
T72950 | 15-PGDH-IN-1 | ||
15-PGDH-IN-1 is an orally active, potent inhibitor of 15-PGDH, exhibiting significant inhibitory activity against recombinant human 15-PGDH with an IC50 value of 3 nM. This compound is utilized in the research of tissue ... | |||
T41267 | PROTAC(H-PGDS)-7 | ||
PROTAC(H-PGDS)-7 is a selective and potent small molecule hematopoietic prostaglandin D synthase (H-PGDS) PROTAC degradation agent that exhibits degradation activity in KU812 cells with a DC50 of 17.3 pM. PROTAC(H-PGDS)-... | |||
T73336 | Ketotifen | HC 20-511 | |
Ketotifen (HC 20-511) is a second-generation, orally active noncompetitive histamine 1 (H1) receptor antagonist and mast cell stabilizer. It inhibits 6-phosphogluconate dehydrogenase (PGD) in vitro and displays antiviral... | |||
T36545 | Prostaglandin D2 methyl ester | Prostaglandin D2 methyl ester | |
Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis. It causes vasodilation, flushing, hypoten... | |||
T71088 | AM-211 sodium | ||
AM-211 sodium is a novel and potent antagonist of the prostaglandin D2 receptor type 2. AM-211 is active in animal models of allergic inflammation. AM211 has high affinity for human, mouse, rat, and guinea pig DP2 and it... | |||
T38389 | Prostaglandin D2 Ethanolamide | Prostaglandin D2 Ethanolamide | |
Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential metabolism of anandamide (arachidonoyl ethanolamide) by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase. The ... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13831 | Prostaglandin D2 | PGD2 | Endogenous Metabolite |
Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals,and is a potent endogenous sleep promoting substances. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02801 | PHGDH Protein, Human, Recombinant (His) | Human | E. coli |
PHGDH is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family. This new family consists of D-isomer-stereospecific enzymes. The conserved residues in this family appear to be the residues involved in the ... | |||
TMPY-02422 | PGD Protein, Human, Recombinant (His) | Human | E. coli |
PGD Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 54.6 kDa and the accession number is P52209. | |||
TMPY-03120 | Prostaglandin D2 Synthase Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Prostaglandin D2 Synthase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.1 kDa and the accession number is P41222. | |||
TMPJ-00690 | PGDS Protein, Human, Recombinant | Human | E. coli |
Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macroph... | |||
TMPY-04077 | HPGDS/PGD2 Protein, Human, Recombinant (His) | Human | E. coli |
HPGDS/PGD2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.2 kDa and the accession number is O60760. | |||
TMPY-04624 | Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.9 kDa and the accession number is O09114-1. | |||
TMPY-02273 | 15-PGDH Protein, Mouse, Recombinant (His) | Mouse | E. coli |
15-PGDH Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30.6 kDa and the accession number is Q8VCC1. | |||
TMPY-01264 | 15-PGDH Protein, Human, Recombinant (His) | Human | E. coli |
15-PGDH Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 29.7 kDa and the accession number is P15428-1. |