par2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T36531	PAR2 (1-6) (mouse, rat)	PAR2 (1-6) (mouse, rat)
	PAR2 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse and rat PAR2. It also corresponds to residues 3...
T35955	PAR2 (1-6) amide (human) (trifluoroacetate salt)	PAR2 (1-6) amide (human) (trifluoroacetate salt)
	PAR2 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR2 and residues 37-42 of the full-lengt...
T8917	PAR-2-IN-1	IUN76750	Protease-activated Receptor
	PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects.		Protease-activated Receptor
TP1046L	PAR-2 Activating Peptide acetate	SLIGRL-NH2 acetate,PAR-2 Activating Peptide acetate(171436-38-7 free base),Protease-Activated Receptor-2 Activating Peptide acetate	Protease-activated Receptor
	PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate) is an agonist of Protease-Activated Receptor-2 (PAR-2).		Protease-activated Receptor
T7513	Protease-Activated Receptor-2, amide	SLIGKV-NH2	Protease-activated Receptor
	Protease-Activated Receptor-2, amide (SLIGKV-NH2) is an agonist of PAR2 (IC50 : 10.4 M)		Protease-activated Receptor
T2370	AC-55541	AOB2796	Proteasome , Protease-activated Receptor
	AC-55541 (AOB2796) is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM.		Proteasome , Protease-activated Receptor
TQ0012	AZ3451		Protease-activated Receptor
	AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).		Protease-activated Receptor
TP1378	2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base)	2-Furoyl-LIGRLO-amide	Protease-activated Receptor
	2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) is a potent and selective protease-activated receptor 2 (PAR2) agonist.		Protease-activated Receptor
T21699L	VKGILS-NH2 Acetate	VKGILS-NH2 Acetate (942413-05-0 Free base)	Protease-activated Receptor
	VKGILS-NH2 Acetate is a reversed amino acid sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist.		Protease-activated Receptor
T7137	I-191		Protease-activated Receptor
	I-191 is a potent antagonist of protease-activated receptor 2 (PAR2), inhibits multiple signaling functions in human cancer cells.		Protease-activated Receptor
T41190	AY 77	Unk-Cha-Chg-NH2	ERK , Calcium Channel , Protease-activated Receptor
	AY 77 (Unk-Cha-Chg-NH2) is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1/2 signaling (ec50 value of Ca2+ release was 40 nM and ec50 value of ERK1/2 phosphorylation was 2 μM). AY 77 can p...		ERK , Calcium Channel , Protease-activated Receptor
TP1904L	FSLLRY-NH2 TFA(245329-02-6 free base)		Protease-activated Receptor
	FSLLRY-NH2 TFA is a is a protease-activated receptor 2 (PAR2) inhibitor. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in iso...		Protease-activated Receptor
TN6872	Trypsin		Protease-activated Receptor
	Trypsin is a serine protease that can be isolated from fish to hydrolyze lysine or arginine carboxy-side proteins. With the anti-inflammatory activity, Trypsin could induce the cell membrane fusion of PDCoV-infected cell...		Protease-activated Receptor
T11370	GB-88		Others
	GB-88 is an selective , oral non-peptide antagonist of PAR2, inhibits PAR2 activated Ca2+ release with an IC50 of 2 μM.		Others
T27406	GB83	GB-83,GB 83
	GB83 is a selective human protease activated receptor 2 (PAR2) antagonist.
T4186	AC-264613	AC264613	Protease-activated Receptor
	AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613(AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macropha...		Protease-activated Receptor
T11369	GB-110		Others
	GB-110 selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM. GB-110 is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist.		Others
T75903	VKGILS-NH2 TFA
	VKGILS-NH2 TFA is a reversed-sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist. It demonstrates no impact on cellular DNA synthesis [1] [2].
T75871	FSLLRY-NH2 TFA
	FSLLRY-NH2 TFA is a protease-activated receptor 2 (PAR2) inhibitor [1] .
T73854	GB-110 hydrochloride
	GB-110 hydrochloride, a potent and orally active nonpeptidic agonist of the protease-activated receptor 2 (PAR2), selectively triggers PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM [1].