keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PAR2 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse and rat PAR2. It also corresponds to residues 39-44 and 37-42 of the mouse and rat full-length sequences, respectively. PAR2 (1-6) induces relaxation in precontracted rat arteries in a concentration-dependent manner, an effect that can be reduced by the nitric oxide synthase inhibitor L-NNA . It inhibits keratinocyte growth in the presence and absence of growth factors. PAR2 (1-6) inhibits LPS-induced pulmonary neutrophil influx and increases in matrix metalloproteinase-2 (MMP-2) activity in mice.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 110.00 | |
5 mg | 35 days | $ 483.00 | |
10 mg | 35 days | $ 853.00 | |
25 mg | 35 days | $ 1,860.00 |
Description | PAR2 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse and rat PAR2. It also corresponds to residues 39-44 and 37-42 of the mouse and rat full-length sequences, respectively. PAR2 (1-6) induces relaxation in precontracted rat arteries in a concentration-dependent manner, an effect that can be reduced by the nitric oxide synthase inhibitor L-NNA . It inhibits keratinocyte growth in the presence and absence of growth factors. PAR2 (1-6) inhibits LPS-induced pulmonary neutrophil influx and increases in matrix metalloproteinase-2 (MMP-2) activity in mice. |
Synonyms | PAR2 (1-6) (mouse, rat) |
Molecular Weight | 657.814 |
Formula | C29H55N9O8 |
CAS No. | 164081-25-8 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: 50 mg/mL
PBS (pH 7.2): 10 mg/mL
Ethanol: 50 mg/mL
DMSO: 50 mg/mL
You can also refer to dose conversion for different animals. More
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PAR2 (1-6) (mouse, rat) 164081-25-8 PAR-2 PAR2 (1 6) (mouse, rat) PAR2 (16) (mouse, rat) PAR 2 PAR2 PAR-2 (1-6) (mouse, rat) inhibitor inhibit