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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16732 | Reproxalap | NS-2,ADX-102 | Others |
Reproxalap (NS-2) covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal. Reproxalap is a reactive aldehyde species sequestering agent for the treatment of the dry eye. | |||
T3214 | NS-398 | N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide,NS398 | COX |
NS-398 (N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide) is a COX-2 inhibitor wih anti-inflammatory activity. | |||
T6481 | Droxinostat | NS 41080 | Apoptosis , HDAC |
Droxinostat (NS 41080) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10. | |||
T16345 | NS13001 | N-(4-chlorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-9-methylpurin-6-amine,N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine | Potassium Channel |
NS13001 (N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine) is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance calcium-activated potassium ch... | |||
T23652 | AFD-21 | AFD21,NS-2 Class 1 antiarrhythmic agent | |
AFD-21 is a class I antiarrhythmic drug. It binds to sodium channels in their inactivated state and exerts use- and voltage-dependent inhibition of sodium channels with unbinding rates comparable to those of class I anti... | |||
T9450 | NS3861 fumarate | ||
NS3861 fumarate is an agonist of nicotinic acetylcholine receptors (nAChRs). NS3861 fumarate is a partial agonist at α3β4 nAChR and binds with high affinity to heteromeric α3β4 nAChR. The binding Ki values of 0.62, 25, 7... | |||
T39503 | Hepatitis Virus C NS3 Protease Inhibitor 2 | ||
Hepatitis Virus C NS3 Protease Inhibitor 2 is a peptide inhibitor derived from a product that targets the NS3 protease of the hepatitis C virus (HCV). Its inhibitory activity against the NS3 protease is characterized by ... | |||
T39292 | NS2 (114-121), Influenza | NS2 (114-121), Influenza | |
NS2 (114-121), Influenza, is a fragment derived from the nonstructural protein 2 (NS2) of the influenza virus. This compound serves as an epitope for influenza research and can be utilized to study the CD8+ cytotoxic T l... | |||
T8494 | NS-3-008 hydrochloride | NS-3-008 HCl | Others |
NS-3-008 hydrochloride (NS-3-008 HCl) is a transcriptional G0/G1 switch 2 (G0s2) inhibitor( IC50 of 2.25 μM). | |||
T4294 | NS 11021 | NS11021 | Potassium Channel |
NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channels | |||
T73572 | NS-8 | ||
NS-8, a pyrrole derivative, activates the calcium (Ca 2+)-sensitive potassium (K+)-channel, leading to the suppression of the micturition reflex through the reduction of afferent pelvic nerve activity. This compound is v... | |||
TMIH-0520 | Selexipag-d7 | ||
Selexipag-d7 is a deuterated compound of Selexipag. Selexipag has a CAS number of 475086-01-2. Selexipag(NS-304) is prostacyclin receptor agonist that causes vasodilation in pulmonary vasculature and is used in the thera... |