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Search Result

Search Results for " nk2 "

40

Compounds

10

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T62164 TNK2-IN-1
TNK2-IN-1 is a TNK2 inhibitor (IC50: 224 nM) that can be used in cancer research.
T78829 JNK2-IN-1 JNK
JNK2-IN-1 (Compound J27), a selective JNK2 inhibitor with a dissociation constant (Kd) of 79.2 µM, exhibits anti-inflammatory effects by attenuating TNF-α and IL-6 secretion via inhibition of the NF-κB/MAPK pathway. It e...
TP1772L Hemokinin 1 (mouse) acetate(208041-90-1 free base) Neurokinin receptor
Hemokinin 1 (mouse) acetate is a selective excitogen 1 receptor agonist with a Ki value of 0.175 nM for the human NK1 receptor and 560 nM for the human NK2 receptor.
TP1883 [Lys5,MeLeu9,Nle10]-NKA(4-10) Neurokinin receptor
Highy selective and potent NK2 receptor agonist (IC50 = 6.1 nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10 nM respectively).
TP1385 Neurokinin A(4-10) TFA(97559-35-8 free base) Neurokinin A(4-10) TFA Neurokinin receptor
Neurokinin A(4-10) TFA(97559-35-8 free base) is a tachykinin NK2 receptor agonist[1].
T20413L Spantide acetate Spantide acetate(91224-37-2 Free base) Neurokinin receptor
Spantide acetate is a selective antagonist of NK1 receptor with Kis of 230 nM and 8150 nM for NK1 and NK2.
TP1899L1 Hemokinin 1 (human) acetate(491851-53-7 free base) Neurokinin receptor
Hemokinin 1 (human) acetate is an endogenous substance P homolog that is a selective agonist at the tachykinin NK1 receptor (IC50 values are 1.8, 370 and 480 nM for NK1, NK3 and NK2 receptors respectively). Has prolifera...
TP1086 Men 10376 TFA(135306-85-3,free) Men 10376 TFA,Neurokinin-2 receptor antagonist TFA Neurokinin receptor
Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) is an effective and selective tachykinin nk-2 receptor antagonist with a K I value of 4.4 M for the nk-2 receptor in the small intestine of rats.
T15415 GR 159897 Others
GR 159897 is a competitive, brain-penetrated non-peptide NK2 receptor antagonist with anti-tumor effects. GR 159897 inhibits binding of [3H]GR100679 to human NK2-CHO cells and rat colon membranes (pKis: 9.51 and 10, resp...
T16039 Ibodutant MEN 15596 Others
Ibodutant is an effective and selective tachykinin NK2 receptor antagonist (pKi: 10.1).
T7559 Neurokinin A(4-10) Neurokinin A(4-10)(TFA) Neurokinin receptor
Neurokinin A(4-10)(TFA) is an agonist of tachykinin NK2 receptor .
T70528 GR-112000
GR-112000 is a peptide-based tachykinin NK2 receptor antagonist.
T25197 Bz-Dab(nbd)-awfpp-nle-NH2 Bz-Dab(nbd)-ala-trp-phe-pro-pro-nle-NH2
Bz-Dab(nbd)-ala-trp-phe-pro-pro-nle-NH2 is a fluorescent NK2 antagonist.
T10892 CS-003 Free base Neurokinin receptor
CS-003 free base (CS-003) is a triple tachykinin receptor antagonist with high affinity for human (neurokinin) NK1, NK2 and NK3 receptors, with Ki values of 2.3 nM and 0.54 nM, respectively And 0.74 nM. CS-003 free base ...
T70432 MEN-10627
MEN-10627 is a polycyclic peptide and tachykinin NK2 receptor antagonist.
T22811 GR 94800 Others
Potent and selective tachykinin NK2 receptor antagonist
T25459 GR 100679 GR100679,GR-100679
GR 100679 is an antagonist of NK2 receptor.
T23316 SB 218795 Neurokinin receptor
SB 218795 is an effective and selective antagonist of NK3 with a Ki 13 nM for hNK3 which is about 90-fold and 7000-fold selectivity over hNK2 and hNK1.
T69295 DNK 333
DNK 333 is a dual neurokinin NK1/NK2 receptor antagonist.
T16842 Saredutant SR 48968C,SR 48968 Others
Saredutant is an antagonist of selective NK2 receptors.
TP1998 MDL 29913 MDL 29,913
NK2 tachykinin receptor selective antagonist.
T22811L GR 94800 acetate GR 94800 acetate (141636-65-9 free base) Neurokinin receptor
GR 94800 acetate is a potent and selective neurokinin 2(NK-2) antagonist.
TP1177 Eledoisin Eledone peptide Neurokinin receptor
Eledoisin (Eledone peptide) is a specific agonist of NK2 and NK3 receptors.Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family of neuropeptides.
T71935 WIN 66306
WIN 66306 is a cyclic heptapeptide antagonist of neurokinin-1 (NK1) and NK2 receptors originally isolated from A. flavipes. It binds to NK1 and NK2 receptors and inhibits contractions induced by substance P in isolated g...
TP1100 [bAla8]-Neurokinin A(4-10) MEN 10210
[bAla8]-Neurokinin A(4-10) is a neurokinin 2 (NK2) receptor agonist.
T75882 [Lys5,MeLeu9,Nle10]-NKA(4-10) TFA
[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA is a potent and highly selective NK2 receptor agonist, exhibiting an IC50 value of 6.1 nM [1].
TP1772 Hemokinin 1 (mouse)
Hemokinin 1 (mouse) is a selective excitogen 1 receptor agonist with a Ki value of 0.175 nM for the human NK1 receptor and 560 nM for the human NK2 receptor.
T75840 Hemokinin 1, human TFA
Hemokinin 1, human TFA acts as a selective full agonist at the tachykinin neurokinin 1 (NK1) receptor, while also being a full agonist at NK2 and NK3 receptors. It is capable of inducing opioid-independent analgesia [1] ...
T76430 GR 87389
GR 87389, a potent NK2 receptor antagonist, competitively inhibits GA 64349-induced contractions in smooth muscle strips of the human detrusor, prostate, and prostatic urethra [1] [2].
TP2023 GR 64349
Potent and selective tachykinin NK2 receptor agonist (EC50 = 3.7 nM in rat colon). Displays > 1000- and > 300-fold selectivity over NK1 and NK3 receptors respectively. Active in vivo.
T75881 GR 64349 TFA
GR 64349 is a potent and highly selective NK2 receptor peptide antagonist, demonstrating an EC50 of 3.7 nM in rat colon. It exhibits over 1000-fold selectivity against NK1 receptors and over 300-fold selectivity against ...
TP1899 Hemokinin 1, human Hemokinin 1 (human)
Endogenous substance P homolog that is a selective agonist at the tachykinin NK1 receptor (IC50 values are 1.8, 370 and 480 nM for NK1, NK3 and NK2 receptors respectively). Has proliferative and antiapoptotic actions on ...
T75880 GR 94800 TFA
GR 94800 TFA is a potent, selective antagonist of the NK 2 receptor peptide, demonstrating pK B values of 9.6 for NK 2, 6.4 for NK 1, and 6.0 for NK 3 receptors, respectively [1] [2].
T76426 [Lys5,MeLeu9,Nle10]Neurokinin A(4-10)
[Lys5,MeLeu9,Nle10]Neurokinin A(4-10) (LMN-NKA), a Neurokinin A analogue, serves as a selective and potent agonist for the NK2 receptor (NK2R). This compound exhibits prokinetic activity, making it a valuable tool for re...
T75837 Spantide I TFA
Spantide I TFA, a selective NK1 receptor antagonist and a substance P analog, exhibits K(i) values of 230 nM for NK1 and 8150 nM for NK2 receptors, respectively. It offers a method to decrease type 1 while increasing typ...
T75742 Neurokinin A(4-10) TFA
Neurokinin A (4-10) TFA is a tachykinin NK 2 receptor agonist [1] .
T71000 RO-5328673
RO-5328673 is a dual NK2/NK3 antagonist. O5328673. [(3)H]RO5328673 bound to a single saturable site on hNK2, hNK3 and gpNK3 with high-affinity. RO5328673 acted as an insurmountable antagonist at both human and guinea-pig...
T70456 Nolpitantium Free Base
Nolpitantium Free Base is a highly selective nonpeptide antagonist of neurokinin-1 (NK1) receptor. Nolpitantium potently, selectively and competitively inhibited substance P binding to NK1 receptors from various animal s...
T16038 Men 10376 Neurokinin-2 receptor antagonist CDK
Men 10376 is a selective antagonist of tachykinin NK-2 receptor. It has a Ki of 4.4 μM for rat small intestine NK-2 receptor.
T20413 Spantide I Spantide
Spantide antagonizes both bombesin & substance P. It is also tachykinin receptor antagonist.

Compounds

TNK2-IN-1
T62164
Synonym:
Target:
JNK2-IN-1
T78829
Synonym:
Target: JNK
Hemokinin 1 (mouse) acetate(208041-90-1 free base)
TP1772L
Synonym:
Target: Neurokinin receptor
[Lys5,MeLeu9,Nle10]-NKA(4-10)
TP1883
Synonym:
Target: Neurokinin receptor
Neurokinin A(4-10) TFA(97559-35-8 free base)
TP1385
Synonym: Neurokinin A(4-10) TFA
Target: Neurokinin receptor
Spantide acetate
T20413L
Synonym: Spantide acetate(91224-37-2 Free base)
Target: Neurokinin receptor
Hemokinin 1 (human) acetate(491851-53-7 free base)
TP1899L1
Synonym:
Target: Neurokinin receptor
Men 10376 TFA(135306-85-3,free)
TP1086
Synonym: Men 10376 TFA,Neurokinin-2 receptor antagonist TFA
Target: Neurokinin receptor
GR 159897
T15415
Synonym:
Target: Others
Ibodutant
T16039
Synonym: MEN 15596
Target: Others
Neurokinin A(4-10)
T7559
Synonym: Neurokinin A(4-10)(TFA)
Target: Neurokinin receptor
GR-112000
T70528
Synonym:
Target:
Bz-Dab(nbd)-awfpp-nle-NH2
T25197
Synonym: Bz-Dab(nbd)-ala-trp-phe-pro-pro-nle-NH2
Target:
CS-003 Free base
T10892
Synonym:
Target: Neurokinin receptor
MEN-10627
T70432
Synonym:
Target:
GR 94800
T22811
Synonym:
Target: Others
GR 100679
T25459
Synonym: GR100679,GR-100679
Target:
SB 218795
T23316
Synonym:
Target: Neurokinin receptor
DNK 333
T69295
Synonym:
Target:
Saredutant
T16842
Synonym: SR 48968C,SR 48968
Target: Others
MDL 29913
TP1998
Synonym: MDL 29,913
Target:
GR 94800 acetate
T22811L
Synonym: GR 94800 acetate (141636-65-9 free base)
Target: Neurokinin receptor
Eledoisin
TP1177
Synonym: Eledone peptide
Target: Neurokinin receptor
WIN 66306
T71935
Synonym:
Target:
[bAla8]-Neurokinin A(4-10)
TP1100
Synonym: MEN 10210
Target:
[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA
T75882
Synonym:
Target:
Hemokinin 1 (mouse)
TP1772
Synonym:
Target:
Hemokinin 1, human TFA
T75840
Synonym:
Target:
GR 87389
T76430
Synonym:
Target:
GR 64349
TP2023
Synonym:
Target:
GR 64349 TFA
T75881
Synonym:
Target:
Hemokinin 1, human
TP1899
Synonym: Hemokinin 1 (human)
Target:
GR 94800 TFA
T75880
Synonym:
Target:
[Lys5,MeLeu9,Nle10]Neurokinin A(4-10)
T76426
Synonym:
Target:
Spantide I TFA
T75837
Synonym:
Target:
Neurokinin A(4-10) TFA
T75742
Synonym:
Target:
RO-5328673
T71000
Synonym:
Target:
Nolpitantium Free Base
T70456
Synonym:
Target:
Men 10376
T16038
Synonym: Neurokinin-2 receptor antagonist
Target: CDK
Spantide I
T20413
Synonym: Spantide
Target:

Recombinant Proteins

Species：
Human (5)
Mouse (5)
Expression System：
Baculovirus Insect Cells (6)
HEK293 Cells (3)
E. coli (1)
Tag：
Tag Free (3)
His, GST (2)
C-His (1)
C-hFc (1)
GST (1)
His (1)
N-10xHis, C-Myc (1)
Cat No. Product Name Species Expression System
TMPY-03290 HGF Protein, Mouse, Recombinant Mouse HEK293 Cells
HGF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 79.3 kDa and the accession number is Q08048-1.
TMPY-03237 HGF Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
HGF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 80.8 kDa and the accession number is Q08048-1.
TMPY-04750 CSNK2A2 Protein, Human, Recombinant Human Baculovirus Insect Cells
CSNK2A2 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 41.4 kDa and the accession number is P19784.
TMPY-00163 SPINK2 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Human serine proteinase inhibitor Kazal-type 2 (SPINK2) functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. The SPINK2 protein ...
TMPY-04441 CK2 alpha/CSNK2A1 Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus Insect Cells
CK2 alpha/CSNK2A1 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 72.9 kDa and the accession number is Q60737.
TMPY-04393 CSNK2A2 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
CSNK2A2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69 kDa and the accession number is P19784.
TMPH-02898 SPINK2 Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
As a strong inhibitor of acrosin, it is required for normal spermiogenesis. It probably hinders premature activation of proacrosin and other proteases, thus preventing the cascade of events leading to spermiogenesis defe...
TMPY-04372 CK2 alpha/CSNK2A1 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
CK2 alpha/CSNK2A1 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 71.4 kDa and the accession number is P68400-1.
TMPY-04758 CK2 alpha/CSNK2A1 Protein, Mouse, Recombinant Mouse Baculovirus Insect Cells
CK2 alpha/CSNK2A1 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 45.3 kDa and the accession number is Q60737.
TMPY-04550 JNK2 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Mitogen-activated protein kinase 9 (MAPK9), also well known as c-Jun N-terminal kinase (JNK2), is a member of the MAP kinase subfamily belonging to the protein kinase superfamily. MAPK9 responds to activation by environm...
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