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Eledoisin

Catalog No. TP1177 CAS 69-25-0

Synonyms: Eledone peptide

Eledoisin (Eledone peptide) is a specific agonist of NK2 and NK3 receptors.Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family of neuropeptides.

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Eledoisin, CAS 69-25-0

Pack Size	Availability	Price/USD
1 mg	4-5 weeks	$ 215.00
5 mg	4-5 weeks	$ 840.00
10 mg	4-5 weeks	$ 1,470.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Eledoisin (Eledone peptide) is a specific agonist of NK2 and NK3 receptors.Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family of neuropeptides.
In vitro	Eledoisin increases basal activity by 24.5±3.7%; however, its stimulation is significantly reduced to 13.1±1.9% in the presence of CP99994 (P<0.01). This effect demonstrates the compound's sensitivity to CP99994, further validated through similar tests with 0.1 μM SR48968 and 0.1 μM SB222200. SR48968 significantly decreases Eledoisin's effect (P<0.01), whereas SB222200 does not alter it. This data collectively indicates that Eledoisin's stimulatory action is diminished by CP99994 and SR48968, which are NK1 and NK2 antagonists, respectively[1].
In vivo	Injection of Eledoisin (0.1-1 nmol/kg) into rats produces a biphasic cardiovascular response that consists of an initial fall of systemic blood pressure (8-15 mm Hg) followed by a rise (20-22 mm Hg).

Synonyms	Eledone peptide
Molecular Weight	1188.4
Formula	C54H85N13O15S
CAS No.	69-25-0

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 18.15 mg/mL (15.27 mM), Sonication and heating are recommended.

References and Literature

1. Lippe C, et al. Eledoisin and Kassinin, but not Enterokassinin, stimulate ion transport in frog skin. Peptides. 2004 Nov;25(11):1971-5.

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Keywords

Eledoisin 69-25-0 GPCR/G Protein Neuroscience Neurokinin receptor Eledone peptide inhibit Inhibitor inhibitor

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