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Neurokinin A(4-10) TFA(97559-35-8 free base)

Catalog No. TP1385   CAS TP1385
Synonyms: Neurokinin A(4-10) TFA

Neurokinin A(4-10) TFA(97559-35-8 free base) is a tachykinin NK2 receptor agonist[1].

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Neurokinin A(4-10) TFA(97559-35-8 free base) Chemical Structure
Neurokinin A(4-10) TFA(97559-35-8 free base), CAS TP1385
Pack Size Availability Price/USD Quantity
1 mg In stock $ 68.00
5 mg In stock $ 263.00
10 mg In stock $ 459.00
25 mg In stock $ 755.00
50 mg In stock $ 1,060.00
100 mg In stock $ 1,430.00
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Purity: 100%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Neurokinin A(4-10) TFA(97559-35-8 free base) is a tachykinin NK2 receptor agonist[1].
In vitro Neurokinin A (NKA) and its truncated form NKA(4-10) are potent spasmogens of human colon circular muscle, an action mediated exclusively via tachykinin NK2 receptors. A structure-activity study of the neurokinin A (NKA) fragment NKA(4-10) is performed to investigate the importance of amino acid residues for receptor efficacy, potency and affinity at the NK2 receptor in human colon circular muscle. A high density of NK2 receptors has been demonstrated in this tissue, using in vitro autoradiography and radioligand binding[1].
Synonyms Neurokinin A(4-10) TFA
Molecular Weight 880.93
Formula C36H55F3N8O12S
CAS No. TP1385

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: < 0.1 mg/mL (insoluble)

TargetMolReferences and Literature

1. Warner FJ, et al. Structure-activity relationship of neurokinin A(4-10) at the human tachykinin NK(2) receptor: the effect of amino acid substitutions on receptor affinity and function. Biochem Pharmacol. 2002 Jun 15;63(12):2181-6.

Related compound libraries

This product is contained In the following compound libraries:
Peptide Compound Library NO PAINS Compound Library

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Keywords

Neurokinin A(4-10) TFA(97559-35-8 free base) TP1385 GPCR/G Protein Neuroscience Neurokinin receptor Neurokinin A TFA(97559-35-8 free base) Neurokinin A(4-10) TFA Neurokinin A(410) TFA(97559358 free base) Neurokinin A TFA Neurokinin A(4 10) TFA(97559 35 8 free base) inhibitor inhibit

 

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