msi — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T12116L	MSI-1701		Others
	MSI-1701 is an analogue of MSI-1436.		Others
T12116	MSI-1436	Aminosterol-1436,Trodusquemine	Others
	MSI-1436 is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM)		Others
T12117	MSI-1436 lactate	Trodusquemine lactate,Aminosterol-1436 lactate	Others
	MSI-1436 lactate is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM)		Others
T12995	Squalamine	MSI-1256	Others
	Squalamine is an aminosterol compound, with potent broad spectrum antiviral activity.		Others
T12996	Squalamine lactate	MSI-1256F	Others
	Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.		Others
T16766	Ro 08-2750
	Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 µM. Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM. Ro 08-2...
T2145	Temsirolimus	NSC 683864,CCI-779	Apoptosis , mTOR , Autophagy
	Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.		Apoptosis , mTOR , Autophagy
T21314	Amsilarotene	TAC-101,TAC 101,TAC101	CDK
	Amsilarotene (TAC101) inhibits the phosphorylation of retinoblastoma gene product (RB) and increases the presence of 2 cyclin-dependent kinases (CDK) inhibitors resulting in cell cycle arrest. This agent also causes a cy...		CDK
T69669	Camsirubicin HCl
	Camsirubicin, also known as GPX-150, MNPR-201, and CNDO1011, is a synthetic non-cardiotoxic analogue of the anthracycline antibiotic doxorubicin with potential antineoplastic activity. Anthracycline analogue GPX-150 inte...
T125382	Extensumside F
	Extensumside F is a useful organic compound for research related to life sciences. The catalog number is T125382 and the CAS number is 2079912-12-0.
T68811	Trimetaphan camsilate
	Trimetaphan camsilate is a drug that counteracts cholinergic transmission at the ganglion type of nicotinic receptors of the autonomic ganglia and therefore blocks both the sympathetic nervous system and the parasympathe...
T125381	Extensumside H
	Extensumside H is a useful organic compound for research related to life sciences. The catalog number is T125381 and the CAS number is 2079912-14-2.
T125383	Extensumside E
	Extensumside E is a useful organic compound for research related to life sciences. The catalog number is T125383 and the CAS number is 2079912-11-9.
T77032	Imsidolimab
	Imsidolimab (ANB 019), a high-affinity, humanized monoclonal antibody targeting IL-36R, antagonizes IL-36 cytokine signal transduction, showing potential in treating generalized pustular psoriasis (GPP) and other inflamm...
T77025	Gimsilumab
	Gimsilumab (MORAb-022), a humanized anti-GM-CSF monoclonal antibody, shows promise in the research of COVID-19 and rheumatoid arthritis (RA) [1] [2].
T125384	Extensumside C
	Extensumside C is a useful organic compound for research related to life sciences. The catalog number is T125384 and the CAS number is 2079912-09-5.
T80548	mSIRK		ERK
	mSIRK (G-Protein βγ Binding Peptide) is a cell-permeable activator of ERK 1/2 with an EC50 of 2.5-5 μM. It disrupts the interaction between the α and βγ subunits, facilitating α subunit dissociation without inducing nucl...		ERK
T25201	Camsirubicin
	Camsirubicin is a drug candidate of antineoplastic.
T73653	Pexiganan
	Pexiganan (MSI 78 free base), a synthetic analog of magainin 2, is a potent, broad-spectrum antimicrobial peptide with oral activity. It is utilized in researching infections, including diabetic foot ulcer infections [1]...
T72216	DPM-1001 trihydrochloride
	DPM-1001 trihydrochloride, an analog of the specific protein-tyrosine phosphatase (PTP1B) inhibitor MSI-1436, is a potent, specific, non-competitive, orally active inhibitor of PTP1B with an IC50 of 100 nM, exhibiting an...