Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 2,420.00 | |
50 mg | 10-14 weeks | $ 3,180.00 | |
100 mg | 10-14 weeks | $ 4,300.00 |
Description | Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity. |
In vitro | Squalamine lactate has a more general effect on the cell signaling cascade, which is common to VEGF and other growth factors[1]. Squalamine blocks the action of VEGF and integrin expression, thereby inhibiting angiogenesis, when bound to calmodulin[2]. |
In vivo | When administered intravitreally and therefore requires intravenous dosing, Squalamine is ineffective . However, systemic dosing has yielded promising results in rats as well as humans[2]. |
Synonyms | MSI-1256F |
Molecular Weight | 718.04 |
Formula | C37H71N3O8S |
CAS No. | 320725-47-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 36.66 mg/mL (51.06 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Squalamine lactate 320725-47-1 Others Squalamine Lactate MSI-1256F inhibitor inhibit