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Search Results for " luciferase "

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Compounds

Cat No. Product Name Synonyms Targets
TP1344 Luciferase Others
Luciferase is a flavin-dependent monooxygenase found in bioluminescent bacteria. Luciferase is an invaluable tool for identifying and characterizing functional variants, allowing investigations of gene expression, intrac...
T38310 Luciferase-IN-1 Reactive Oxygen Species , Antibacterial , Antifungal
Luciferase-IN-1 is a luciferase inhibitor that can be used to study bacterial and fungal infections.
T9943 Firefly luciferase-IN-1 Others
Firefly luciferase-IN-1 is a 2-benzylidene tetrahydronaphthone derivative and can be used as a firefly luciferase inhibitor in kit.
TP1774 Luciferase, firefly
Luciferase, firefly is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles. The enzyme catalyses the oxidation of firefly luciferin, requiring oxygen and ATP.
T82398 Firefly Luciferase circRNA
Firefly Luciferase circRNA, originally isolated from Photinus pyralis (Firefly), expresses a luciferase protein and serves as an optimal marker for monitoring and optimizing transfection efficiency; it is also recommende...
T82397 Firefly Luciferase mRNA(N1-Me-Pseudo UTP)
Firefly Luciferase mRNA, derived from Photinus pyralis (Firefly), codes for a bioluminescent enzyme widely utilized as a reporter in gene regulation and function analyses. This enzyme facilitates assays pertaining to gen...
T1971 WAY-262611 Wnt/beta-catenin
WAY262611 is a Wnt/β-catenin agonist and an inhibitor of Dkk1. It increases bone formation rate with EC50 of 0.63 μM in TCF-luciferase assay.
T5537 IDF-11774 HIF/HIF Prolyl-Hydroxylase , HIF
IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).
T60051 VPC-18005 Others
VPC-18005 is a luciferase inhibitor. VPC-18005 inhibits ERG-induced transcription and interacts directly with the ERG-ETS domain thereby disrupting the ERG binding to DNA.
T3313 D-Luciferin Firefly luciferin,D-(-)-Luciferin Others
D-Luciferin (D-(-)-Luciferin) is a popular bioluminescent substrate of luciferase in the presence of ATP, used in luciferase-based bioluminescence imaging and cell-based high-throughput screening applications.
T19122 3-Methylvaleric Acid Others , Endogenous Metabolite
3-Methylvaleric Acid is an edible grade flavor present in tobacco.3-Methylvaleric Acid enhances intracellular cAMP accumulation and CRE-luciferase activity in CHO-K1 cells and HEK293 cells.
T8086 Decyl aldehyde Others , Endogenous Metabolite
Decyl aldehyde is a ten-carbon aldehyde that is a substrate for bacterial luciferase.
T15030 CycLuc1 Others
CycLuc1 is a brain penetrant luciferase substrate. CycLuc1 may be a superior BLI substrate as compared to D-luciferin for monitoring tumor growth of intracranial GBM xenografts.
T22062 CCG-100602 Rho , Ras
CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).
TN7236 Cephalandole B IL Receptor
cephalandole B, an indole alkaloid isolated from cyanide, significantly inhibited IL-17A gene expression and suppressed IL-17A luciferase reporter in Jukat cells in a dose-dependent manner.
T36711 FM19G11 FM19G11,HIF-1alpha/2alpha Inhibitor HIF
FM19G11 is an inhibitor of hypoxia inducible factor (HIF) α-subunit (IC50 = 80 nM in hypoxia induced luciferase assay).
T4139 D-Luciferin potassium D-Luciferin K Salt,D-Luciferin Potassium Salt Others
D-Luciferin potassium (D-Luciferin K Salt) is a popular bioluminescent substrate of luciferase in the presence of ATP.
T22374 N-(beta-Ketocaproyl)-L-hoMoserine lactone N-(β-Ketocaproyl)-L-hoMoserine lactone,N-(Ketocaproyl)-L-homoserine lactone,N-(β-Ketocaproyl)-L-hoMoserine lactone Others
N-(beta-Ketocaproyl)-L-hoMoserine lactone (N-(Ketocaproyl)-L-homoserine lactone) is a component of quorum regulatory sensing and an autoinducer of P. fischeri luciferase.
TN1334 7-Methoxyrosmanol 7-O-Methylrosmanol cAMP
7-Methoxyrosmanol (7-O-Methylrosmanol) can effectively suppress FSK-induced luciferase expression under the control of the CRE, PEPCK-C and G6Pase gene promoters, it may contribute to its antihyperglycemic activity.
T19743 D-Luciferin Sodium Others
D-Luciferin Sodium is a heterocyclic light-emitting compound and natural ligand for luciferase used to detect cell activity. The salt form of luciferin dissolves in water or other typical buffers.
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