lipase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T11199	Endothelial lipase inhibitor-1		Lipase
	Endothelial lipase inhibitor-1 is a potent endothelial lipase inhibitor with an IC50 of 49 nM.		Lipase
T39383	Lipase Substrate
	Lipase Substrate is a substrate of lipase to detect activity.
T73610	Lipoprotein lipase
	Lipoprotein lipase, a multifunctional enzyme present in adipose tissue, heart, skeletal muscle, islets, and macrophages, plays a crucial role in normal lipoprotein metabolism, and the distribution and utilization of tiss...
T65529	Lipase, triacylglycerol
	Lipase, triacylglycerol is a useful organic compound for research related to life sciences. The catalog number is T65529 and the CAS number is 9001-62-1.
T61294	Monoacylglycerol lipase inhibitor 1
	Monoacylglycerol lipase inhibitor 1, also known as compound 13 [1], is a potent inhibitor of monoacylglycerol lipase.
T63015	Pancreatic lipase/Carboxylesterase 1-IN-1
	Pancreatic lipase/Carboxylesterase 1-IN-1 (Compound 39) is a potent, dual inhibitor of pancreatic lipase (PL) and human carboxylesterase 1A (hCES1A), acting on PL (IC50: 2.13 μM) and hCES1A (IC50: 0.055 μM).
T15082	DDAO		Others
	DDAO is a promising near-infrared (NIR) red fluorescent probe with long emission wavelength (λem = 656 nm) and tunable excitation wavelength (600-650 nm). It can de desiged for detection of the activities of different en...		Others
T1875	Atglistatin		Lipase
	Atglistatin is a highly effective, specific and competitive ATGL inhibitor with an IC50 of ~0.7 μM for inhibition of lipolysis in vitro, and no toxicity when the concentration up to 50 μM.		Lipase
T5737	Euphol		Others , Lipase , Endogenous Metabolite
	Euphol, an alcohol tetracyclic triterpene, has a wide range of pharmacological properties and is considered to have anti-inflammatory action.		Others , Lipase , Endogenous Metabolite
T15635	JZP-430		Lipase , MAGL
	JZP-430 is an effective, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50: 44 nM). It also shows ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL...		Lipase , MAGL
T15614	JJKK 048		Lipase
	JJKK 048 is a potent and selective MAGL inhibitor.		Lipase
T9687	MAGL-IN-4	His121 ARG57	Lipase
	MAGL-IN-4 (His121 ARG57) is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.		Lipase
T8974	ML-211		Others
	ML-211 is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and the related LYPLA2 (IC50 = 30 nM)		Others
T9967	MAGL-IN-5		Lipid
	MAGL-IN-5 is a non-selective lipase inhibitor.		Lipid
T5353	ABX-1431	Elcubragistat	Lipase
	ABX-1431 (Elcubragistat) is a selective and orally available CNS-penetrant monoacylglycerol lipase (MAGL/MGLL) inhibitor (IC50: 14 nM).		Lipase
T15632	JW 642		Lipase
	JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL) (IC50: 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively).		Lipase
T17260	WWL70		Lipase , MAGL
	WWL70 is a selective alpha/beta hydrolase domain 6 inhibitors (IC50: 70 nM).		Lipase , MAGL
T41160	Lalistat 2		Lipase
	Lalistat 2 is a selective inhibitor of lysosomal acid lipase with IC50 of 152 nM and exhibits no inhibition of human pancreatic lipase or bovine milk lipoprotein lipase (up to 10 μM).		Lipase
T4052	KML29		Lipase
	KML29 is highly selective and effective monoacylglycerol lipase (MAGL) inhibitor. It has effective inhibition of human/mouse/rat MAGL (IC50: 5.9/15/43 nM). It has not inhibitory for FAAH (IC50 > 50 μM). It also effective...		Lipase
T2338	JZL195		FAAH , Lipase , Autophagy
	JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.		FAAH , Lipase , Autophagy