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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8081 | LC3-mHTT-IN-AN1 | Others , Autophagy , ATTECs | |
LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B. LC3-mHTT-IN-AN1 targeted mHTT to autophagosomes reduces the levels of mHTT in an allele-selective manner... | |||
T5181 | CA-5f | Apoptosis , Autophagy | |
CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion. | |||
T61871 | DC-LC3in-D5 | ||
DC-LC3in-D5 is a chemical compound that functions as an autophagy inhibitor by diminishing the process of LC3B lipidation. It forms a binding association with LC3B, disrupting the LC3B-LBP2 interaction with an IC50 of 20... | |||
T61547 | ATG7-IN-2 | ||
ATG7-IN-2 (compound 1) is a highly potent inhibitor of the ATG7 protein, displaying an IC 50 value of 0.089 μM. This compound effectively suppresses the activity of autophagy marker LC3B, thereby regulating the autophagy... | |||
T61552 | ATG7-IN-3 | ||
ATG7-IN-3 (compound 18) is an effective inhibitor of ATG7, with a potency of 0.048 μM as determined by its IC50 value. It exhibits inhibitory actions on autophagy. Moreover, ATG7-IN-3 effectively hampers the development ... | |||
T38469 | (Rac)-Z-Phe-Phe-FMK | Cathepsin L-IN-2 | Beta Amyloid , Cysteine Protease |
(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes . | |||
T36846 | Chromomycin A2 | ||
Chromomycin A2 is an aureolic acid that has been found in several marine actinomycetes and has antibacterial and anticancer activities. Chromomycin A2 inhibits the growth of B. subtilis in an agar diffusion assay. It als... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5070 | LC3-mHTT-IN-AN2 | 5,7-Dihydroxy-4-phenylcoumarin | Antibacterial , Autophagy , ATTECs |
LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) is found in the plant Passiflora serratodigitata with the antibacterial activity. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03749 | LC3B Protein, Human, Recombinant (His) | Human | E. coli |
MAP1LC3B (Microtubule Associated Protein 1 Light Chain 3 beta, also known as LC3B) is a Protein Coding gene. The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are in... | |||
TMPJ-01321 | MAP1LC3B Protein, Human, Recombinant | Human | E. coli |
Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) is a member of the highly conserved ATG8 protein family. ATG8 proteins are present in all known eukaryotic organisms. MAP1LC3B is one of the four genes in t... |