Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B. LC3-mHTT-IN-AN1 targeted mHTT to autophagosomes reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 119.00 | |
2 mg | In stock | $ 168.00 | |
5 mg | In stock | $ 255.00 | |
10 mg | In stock | $ 378.00 | |
25 mg | In stock | $ 639.00 | |
50 mg | In stock | $ 913.00 | |
100 mg | In stock | $ 1,230.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 279.00 |
Description | LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B. LC3-mHTT-IN-AN1 targeted mHTT to autophagosomes reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons. |
In vitro | LC3-mHTT-IN-AN1 targeted mHTT to autophagosomes, reduced mHTT levels in an allele-selective manner, and rescued disease-relevant phenotypes in cells and in vivo in fly and mouse models of Huntington's disease. |
Molecular Weight | 411.04 |
Formula | C15H9Br2NO3 |
CAS No. | 486443-73-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 120 mg/ml(291.94 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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LC3-mHTT-IN-AN1 486443-73-6 Autophagy Others PROTAC ATTECs Autophagosome-tethering compounds LC3mHTTINAN1 LC3 mHTT IN AN1 Inhibitor LC-3-mHTT-IN-AN1 inhibit inhibitor