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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2192 | Indazole | Sodium Channel | |
Indazole is also called benzpyrazole or isoindazone. Its derivatives exhibit a wide range of biological activities. Indazole and its derivatives can be used in the research of cancer, neurological diseases, cardiovascula... | |||
T25534 | Indazole-Cl | Indazole Cl | Estrogen/progestogen Receptor |
Indazole-Cl is a selective ERß agonist and a selective estrogen receptor modifier (SERM). | |||
T83625 | INOS-IN-14 | 3-bromo-1H-indazole-7-carbonitrile | NOS |
iNOS-IN-14 (3-bromo-1H-indazole-7-carbonitrile) is a potent nitric oxide synthase (NOS) inhibitor that inhibits the NADPH oxidase activity of nNOS. | |||
T28886 | Suprafenacine | N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide | Microtubule Associated |
Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2/M phase. Suprafenacine ... | |||
T22988 | MK-4827 Racemate | Niraparib Racemate,2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide | PARP |
MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1. | |||
T32417 | KP1019 | FFC14A,KP 1019,indazolium trans-tetrachlorobis(1H-indazole)ruthenate-(III) | |
KP1019 is now discontinued. | |||
Fr21265 | 2-Methyl-2H-indazole-3-carboxylic acid | ||
2-Methyl-2H-indazole-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is Fr21265 and the CAS number is 34252-44-3. | |||
T10107 | 3-Bromo-7-nitroindazole | NOS | |
3-Bromo-7-nitroindazole is a more potent and selective inhibitor of neuronal nitric oxide synthase (nNOS) than eNOS or iNOS. It affects the intercellular messenger NO synthesis throughout the brain and body. | |||
T1369 | 1-Methylindazole-3-carboxylic acid | Others | |
1-Methylindazole-3-carboxylic acid is an excellent solvent with a proper boiling point. | |||
T7474 | 7-Nitroindazole | NOS | |
7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS. | |||
T67133 | 6-Hydroxyindazole | ||
6-Hydroxyindazole is a useful organic compound for research related to life sciences. The catalog number is T67133 and the CAS number is 23244-88-4. | |||
T0239 | Lonidamine | AF1890,DICA,Diclondazolic Acid | Apoptosis , Hexokinase , Mitochondrial Metabolism |
Lonidamine (Diclondazolic Acid) is an indazole carboxylic acid derivative, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK). | |||
T64396 | Antiviral agent 38 | Antiviral | |
2H-Pyrido[2',1':3,4]pyrazino[1,2-b]indazole-3-carboxylic acid, 6-(1, 1-Dimethylethyl)-6, 7-Dihydro-10 -(3-methoxypropoxy)-2-oxo-, (6R)- has antibacterial and antiviral activity and can be used to study Hepatitis B virus. | |||
T8807 | Benzydamine | Others | |
Benzydamine is a benzyl-indazole having analgesic, antipyretic, and anti-inflammatory effects. Benzydamine is used to reduce post-surgical and post-traumatic pain and edema and to promote healing. | |||
T30103 | APP-CHMINACA | PX-3,PX3 | |
APP-CHMINACA is a synthetic cannabinoid (CB) featuring a 1-(cyclohexylmethyl)-1H-indazole-3-carboxamide (CHMINACA) base. It displays a 10-fold greater affinity for the central CB1 receptor than that of JWH 018. | |||
T28006 | MDMB-CHMINACA | (S)-MDMB-CHMINACA | |
MDMB-CHMINACA, an indazole-based synthetic cannabinoid, acts as a potent agonist of the CB1 receptor. | |||
T27013 | CHS-111 | CHS 111 | |
CHS-111 is a benzyl indazole compound. CHS-111 inhibits superoxide anion (O(2)(-)) generation. CHS-111 reduces the fMLP-stimulated PLD activity (IC(50) 3.9±1.2μM). CHS-111 inhibits the interaction of PLD1 with ADP-ribosy... | |||
T28320 | PD 121373 | PD121373,PD-121373 | |
PD 121373 is a Benzothiopyrano-indazole cpd. The benzothiopyranoindazoles are potent inhibitors of nucleic acid synthesis, reducing both DNA and RNA synthesis to the same extent at similar concentrations. | |||
T19322 | FKK | Others | |
FKK is an indazole derivative and also a novel bronchodilator. | |||
T28310 | PD 114595 | PD-114595,PD114595 | |
PD 114595 is a Benzothiopyrano-indazole cpd. PD 114595 belongs to a class of DNA complexers, PD 114595 has curative properties against murine solid tumor models. |