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Search Results for " indazole "

20

Compounds

Cat No. Product Name Synonyms Targets
T2192 Indazole Sodium Channel
Indazole is also called benzpyrazole or isoindazone. Its derivatives exhibit a wide range of biological activities. Indazole and its derivatives can be used in the research of cancer, neurological diseases, cardiovascula...
T25534 Indazole-Cl Indazole Cl Estrogen/progestogen Receptor
Indazole-Cl is a selective ERß agonist and a selective estrogen receptor modifier (SERM).
T83625 INOS-IN-14 3-bromo-1H-indazole-7-carbonitrile NOS
iNOS-IN-14 (3-bromo-1H-indazole-7-carbonitrile) is a potent nitric oxide synthase (NOS) inhibitor that inhibits the NADPH oxidase activity of nNOS.
T28886 Suprafenacine N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide Microtubule Associated
Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2/M phase. Suprafenacine ...
T22988 MK-4827 Racemate Niraparib Racemate,2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide PARP
MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.
T32417 KP1019 FFC14A,KP 1019,indazolium trans-tetrachlorobis(1H-indazole)ruthenate-(III)
KP1019 is now discontinued.
Fr21265 2-Methyl-2H-indazole-3-carboxylic acid
2-Methyl-2H-indazole-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is Fr21265 and the CAS number is 34252-44-3.
T10107 3-Bromo-7-nitroindazole NOS
3-Bromo-7-nitroindazole is a more potent and selective inhibitor of neuronal nitric oxide synthase (nNOS) than eNOS or iNOS. It affects the intercellular messenger NO synthesis throughout the brain and body.
T1369 1-Methylindazole-3-carboxylic acid Others
1-Methylindazole-3-carboxylic acid is an excellent solvent with a proper boiling point.
T7474 7-Nitroindazole NOS
7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS.
T67133 6-Hydroxyindazole
6-Hydroxyindazole is a useful organic compound for research related to life sciences. The catalog number is T67133 and the CAS number is 23244-88-4.
T0239 Lonidamine AF1890,DICA,Diclondazolic Acid Apoptosis , Hexokinase , Mitochondrial Metabolism
Lonidamine (Diclondazolic Acid) is an indazole carboxylic acid derivative, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK).
T64396 Antiviral agent 38 Antiviral
2H-Pyrido[2',1':3,4]pyrazino[1,2-b]indazole-3-carboxylic acid, 6-(1, 1-Dimethylethyl)-6, 7-Dihydro-10 -(3-methoxypropoxy)-2-oxo-, (6R)- has antibacterial and antiviral activity and can be used to study Hepatitis B virus.
T8807 Benzydamine Others
Benzydamine is a benzyl-indazole having analgesic, antipyretic, and anti-inflammatory effects. Benzydamine is used to reduce post-surgical and post-traumatic pain and edema and to promote healing.
T30103 APP-CHMINACA PX-3,PX3
APP-CHMINACA is a synthetic cannabinoid (CB) featuring a 1-(cyclohexylmethyl)-1H-indazole-3-carboxamide (CHMINACA) base. It displays a 10-fold greater affinity for the central CB1 receptor than that of JWH 018.
T28006 MDMB-CHMINACA (S)-MDMB-CHMINACA
MDMB-CHMINACA, an indazole-based synthetic cannabinoid, acts as a potent agonist of the CB1 receptor.
T27013 CHS-111 CHS 111
CHS-111 is a benzyl indazole compound. CHS-111 inhibits superoxide anion (O(2)(-)) generation. CHS-111 reduces the fMLP-stimulated PLD activity (IC(50) 3.9±1.2μM). CHS-111 inhibits the interaction of PLD1 with ADP-ribosy...
T28320 PD 121373 PD121373,PD-121373
PD 121373 is a Benzothiopyrano-indazole cpd. The benzothiopyranoindazoles are potent inhibitors of nucleic acid synthesis, reducing both DNA and RNA synthesis to the same extent at similar concentrations.
T19322 FKK Others
FKK is an indazole derivative and also a novel bronchodilator.
T28310 PD 114595 PD-114595,PD114595
PD 114595 is a Benzothiopyrano-indazole cpd. PD 114595 belongs to a class of DNA complexers, PD 114595 has curative properties against murine solid tumor models.
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