import — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8741	MitoBloCK-10	3-fluoro-N'-[(E)-(5-nitrothiophen-2-yl)m	Others
	MitoBloCK-10 (3-fluoro-N'-[(E)-(5-nitrothiophen-2-yl)m) inhibits Tim44 binding to the precursor and to Hsp70.MitoBloCK-10 is the first small molecule modulator to attenuate protein-associated motor (PAM) complex activity...		Others
T7535	RGX-202	β-GPA,3-Guanidinopropionic Acid	AMPK , PPAR
	RGX-202 (β-GPA) is a creatine analog that alters skeletal muscle energy expenditure. It reduces cellular ATP, creatine, and phosphocreatine levels and stimulates AMP-activated protein kinase (AMPK), activating PPARγ coac...		AMPK , PPAR
T3445	Importazole		Apoptosis , Others
	Importazole is an inhibitor of the nuclear transport receptor importin-β.		Apoptosis , Others
T3445L	Importazole HCl (662163-81-7 free base)	Importazole hydrochloride,Importazole HCl,Importazole
	Importazole specifically inhibits the importin-β likely by altering its interaction with RanGTP.
T27612	INI-43	INI 43,INI43	Others
	INI-43, an inhibitor of Nuclear Import-43, shows a significant cytotoxic effect on various cervical and oesophageal cancer cell lines by targeting Kpnβ1 and interferes with the nuclear localization of Kpnβ1 and known Kpn...		Others
T8782	MitoBloCK-11 (MB-11)		Others
	MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, con...		Others
T60165	VB124		Monocarboxylate transporter
	VB124 is an orally active, potent, and selective MCT4 inhibitor, demonstrating specificity in hindering lactate efflux, with IC50 values of 8.6 nM and 19 nM for lactate import and export, respectively, in MDA-MB-231 cell...		Monocarboxylate transporter
T81675	NICE-01	AP1867-PEG2-JQ1,AP-PEG2-JQ1
	NICE-01 (AP1867-PEG2-JQ1; AP-PEG2-JQ1) is a bifunctional compound that facilitates the nuclear import of cytosolic cargoes by leveraging the nuclear-localized bromodomain-containing protein 4 (BRD4) as a carrier for thei...
T38153	NF-κB Inhibitor (trifluoroacetate salt)
	NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells.1It blocks the...
TP1830	SV40 large T antigen NLS
	SV40 large T antigen NLS is from Large T antigen residue 47 to 55, enables protein import into cell nucleus. This peptide is generated from Large T antigen residue 47 to 55.
T37559	NF-κB Control
	NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It bloc...
TP1830L	SV40 large T antigen NLS acetate		Others
	SV40 large T antigen NLS acetate is from Large T antigen residue 47 to 55, enables protein import into cell nucleus.		Others
T76419	Protein Kinase C γ Peptide
	Protein Kinase C (gamma) Peptide, a fragment of Protein Kinase Cγ, plays a role in dominant ataxia by inhibiting the nuclear import of aprataxin, which is associated with recessive ataxia [1].
T24692	QAQ dichloride
	QAQ dichloride is a photoswitchable compound that blocks voltage-gated Na v and K v channels. Its channel-blocking activity is observed in the trans form of the azobenzene photoswitch, while the cis form does not exhibit...
T60511	Theophylline sodium glycinate
	Theophylline (1,3-Dimethylxanthine) sodium glycinate is a potent inhibitor of phosphodiesterase (PDE) that inhibits PDE3 activity to relax airway smooth muscle. Theophylline sodium glycinate can be used for the research ...