igf1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T76795	Xentuzumab	BI 836845	Akt , IGF-1R
	Xentuzumab (BI836845) is a recombinant monoclonal antibody to humanised IGF ligand that inhibits IGF1 and IGF2 growth-promoting signalling and inhibits AKT activation for the study of solid tumours.
T76810	Ganitumab	AMG 479	IGF-1R
	Ganitumab (AMG 479) is a highly potent monoclonal antibody to type 1 insulin-like growth factor receptor (IGF1R). Ganitumab is recognized to bind to IGF1R at low concentration with KD value of 0.22 nM. Ganitumab can inhi...
T80605	Dusigitumab	MEDI 573	IGF-1R
	Dusigitumab (MEDI 573) is a human IgG2λ monoclonal antibody targeting the insulin-like growth factors IGF2 and IGF1, offering therapeutic potential for conditions related to these proteins [1].
T76746	Figitumumab
	Figitumumab (CP-751871) is a fully human monoclonal antibody targeting the insulin-like growth factor 1 receptor (IGF1R) with high potency. By inhibiting the binding of IGF1 to IGF1R, figitumumab achieves an IC50 value o...

Cat No.	Product Name	Synonyms	Targets
T3871	Daucosterol	Alexandrin,Sitogluside,β-Sitosterol β-D-glucoside,Eleutheroside A	Glucosidase
	Daucosterol (Sitogluside) has proliferation-enhancing activity, may be involved in the IGF1-AKT pathway. Daucosterol(β-Sitosterol β-D-glucoside) has efficient and inexpensive neuroprotectant effect, to contribute to IGF1...

Recombinant Proteins

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Expression System：

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Cat No.	Product Name	Species	Expression System
TMPY-06982	IGF1/IGF-I Protein, Human, Recombinant	Human	E. coli
	IGF1/IGF-I Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.8 KDa. and the accession number is P05019-1.
TMPY-04878	IGF1/IGF-I Protein, Mouse, Recombinant	Mouse	P. pastoris (Yeast)
	IGF1/IGF-I Protein, Mouse, Recombinant is expressed in yeast. The predicted molecular weight is 7.7 kDa and the accession number is E9PU89.
TMPY-00834	IGF1R/CD221 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IGF1R/CD221 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81 kDa and the accession number is P08069.
TMPY-04942	IGF1 LR3 Protein, Human, Recombinant	Human	P. pastoris (Yeast)
	IGF1 LR3 Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 9.1 kDa and the accession number is P05019-1.
TMPH-00273	IGF1/IGF-I Protein, Bovine, Recombinant (hFc)	Bovine	P. pastoris (Yeast)
	IGF1/IGF-I Protein, Bovine, Recombinant (hFc) is expressed in yeast with N-hFc tag. The predicted molecular weight is 34.3 kDa and the accession number is P07455.
TMPH-03314	IGF1/IGF-I Protein, Rat, Recombinant (GST)	Rat	E. coli
	N/A. IGF1/IGF-I Protein, Rat, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 34.7 kDa and the accession number is P08025.
TMPK-00083	IGF1/IGF-I Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	The insulin family consists of insulin, insulin-like growth factor 1 (IGF-1), insulin-like growth factor 2 (IGF-2), their receptors (IR, IGF-1R and IGF-2R), and their binding proteins.Insulin-like growth factor I (IGF-I)...
TMPY-04360	IGF1R/CD221 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	IGF1R/CD221 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 74.6 kDa and the accession number is P08069.
TMPY-06905	IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 106.14 kDa and the accession number is NP_000866.1.
TMPJ-00781	LR3-IGF-1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-termin...
TMPK-00455	IGF1R/CD221 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, prot...
TMPK-00658	IGF1R/CD221 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, prot...
TMPK-00456	IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated	Human	HEK293 Cells
	The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, prot...
TMPY-06195	IGF1R/CD221 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	IGF1R/CD221 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 105.2 kDa and the accession number is E9QNX9.
TMPY-04552	AKT1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to ...
TMPH-01536	ITGB4 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG...
TMPH-03390	TRPV2 Protein, Rat, Recombinant (His)	Rat	E. coli
	Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce phys...
TMPY-02194	SOCS3 Protein, Human, Recombinant (His & Trx)	Human	E. coli
	Suppressor of cytokine signaling 3, also known as SOCS-3, Cytokine-inducible SH2 protein 3, CIS-3, STAT-induced STAT inhibitor 3, SOCS3 and CIS3, is a protein which is widely expressed with high expression in heart, plac...