hdac — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T63399L	MTOR/HDAC-IN-1 HCl	mTOR/HDAC-IN-1 HCl（2815286-02-1 Free base)	HDAC , mTOR
	mTOR/HDAC-IN-1 HCl is a potent dual inhibitor of mTOR and HDAC with potential anti-inflammatory, anti-proliferative, autophagy and apoptosis-inducing effects for cancer research.		HDAC , mTOR
T60082	HDAC-IN-40		HDAC
	HDAC-IN-40 is a potent alkoxyamide-based HDAC inhibitor with Ki of 60 nM and 30 nM for HDAC2 and HDAC6, respectively. HDAC-IN-40 had antitumor effects		HDAC
T8508	HDAC-IN-3	GSK3117391A	HDAC
	HDAC-IN-3 (GSK3117391A) is a potent histone deacetylase (HDAC) inhibitor, and treatment chronic inflammatory disorders.		HDAC
T77334	HDAC-IN-57		Apoptosis , HDAC
	HDAC-IN-57 is an orally active pan-inhibitor of histone deacetylase (HDAC), inhibiting HDAC1, HDAC2, HDAC6, and HDAC8 with IC50 values of 2.07 nM, 4.71 nM, 2.4 nM, and 107 nM, respectively. HDAC-IN-57 inhibits LSD1 with ...		Apoptosis , HDAC
T2025	HDAC-IN-7	HBI-8000,CS055,Chidamide impurity	HDAC
	HDAC-IN-7 (HBI-8000) (Chidamide impurity) is an impurity of Chidamide. Chidamide is a potent and orally bioavailable inhibitor of HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10).		HDAC
T73181	HDAC-IN-51		HDAC
	HDAC-IN-51 is an HDAC inhibitor.		HDAC
T10245	ACY-957	HDAC Inhibitor C001	HDAC
	ACY-957 (HDAC Inhibitor C001) is an orally active and selective inhibitor of HDAC1 and HDAC2 (IC50s: 7 nM, 18 nM, and 1300 nM against HDAC1/2/3) and shows no inhibition on HDAC4/5/6/7/8/9.		HDAC
T67878	HDAC-IN-52		HDAC
	HDAC-IN-52 is a pyridine-containing HDAC inhibitor that inhibits HDAC1, HDAC2, HDAC3 and HDAC10 with IC50s of 0.189, 0.227, 0.440 and 0.446 μM, respectively. HDAC-IN-52 can be used in cancer research.		HDAC
T25489	HDAC-IN-20	HDACIN20,HDAC-inhibitor-20,HDAC inhibitor 20
	HDAC-IN-20 is used as an HDAC inhibitor that acts by preventing HDAC-mediated diseases.
T3661	Citarinostat	ACY241,HDAC-IN-2	HDAC
	ACY-241, also known as Citarinostat (ACY241), is a potent, selective and orally available histone deacetylase (HDAC) inhibitor, with potential antineoplastic activity. Upon oral administration, ACY-241 inhibits the activ...		HDAC
T2078	Fimepinostat	CUDC-907,PI3K/HDAC Inhibitor,CUDC 907	Apoptosis , PI3K , HDAC
	Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan-histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, C...		Apoptosis , PI3K , HDAC
T39990	HDAC-IN-26
	HDAC-IN-26 is a highly selective class I HDAC inhibitor with an EC 50 value of 4.7 nM.
T6392	AR42	OSU-HDAC42,AR-42,AR 42,HDAC-42	HDAC
	AR42 (OSU-HDAC42) is an HDAC inhibitor (IC50: 30 nM).		HDAC
T11543	HDAC-IN-5		HDAC
	HDAC-IN-5 is a histone deacetylase (HDAC) inhibitor.		HDAC
T11542	HDAC-IN-4		HDAC
	HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor (pIC50s: 7.2 and 6.8 in BRET assay) with antitumoral activity.		HDAC
T12455	PI3K/HDAC-IN-1		PI3K
	PI3K/HDAC-IN-1 is a potent PI3K and HDAC dual inhibitor(IC50s of 8.1 nM and 1.4 nM, respectively).		PI3K
T62708	HDAC-IN-37
	HDAC-IN-37 is a potent inhibitor of HDAC, acting on HDAC1 (IC50: 0.0551 μM), HDAC3 (IC50: 1.24 μM), HDAC8 (IC50: 0.948 μM) and HDAC6 (IC50: 34.2 μM). HDAC-IN-37 is able to slowly induce histone acetylation. HDAC-IN-37 pr...
T61916	HDAC-IN-35
	HDAC-IN-35 (Compound 14) is an effective and selective inhibitor of VEGFR-2 and HDAC, with IC50 values of 13.2 and 0.166 μM for VEGFR-2 and HDAC6, respectively.
T73179	HDAC-IN-50
	HDAC-IN-50, a potent, orally active inhibitor targeting both FGFR (Fibroblast Growth Factor Receptor) and HDAC (Histone Deacetylase), exhibits IC50 values of 0.18, 1.2, 0.46, 1.4, 1.3, 1.6, 2.6, 13 nM for FGFR1, FGFR2, F...
T74783	HDAC-IN-53		HDAC
	HDAC-IN-53 is an orally active, selective inhibitor of HDAC1-3, demonstrating IC50 values of 47 nM, 125 nM, and 450 nM, respectively. It exhibits no inhibitory effects on class II HDACs (HDAC4, 5, 6, 7, 9; IC50 >10 μM). ...		HDAC