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Search Results for " gabab "

20

Compounds

Cat No. Product Name Synonyms Targets
T11137 (E)-GABAB receptor antagonist 1 GABA Receptor
(E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM. GABAB receptor antagonist 1 is ...
T11350 GABAB receptor antagonist 1 GABA Receptor
(E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM.GABAB receptor antagonist 1 is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric ac...
T21793 CGP 35348 GABA Receptor
CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after neonatal brain damage in albino mice.
T4363 CGP52432 CGP 52432 GABA Receptor
CGP52432 is a very potent antagonist of GABAB receptors (IC50 = 85 nM).
T4440 Saclofen GABA Receptor
Saclofen is a sulfonic analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that acts as a competitive antagonist of the GABAB receptor (IC50: 7.8 μM).1 This compound can be used to determine the function...
T4522 SSD114 HCl GABA Receptor
SSD114 is a novel GABAB receptor positive allosteric modulator.
T68087 Inaperisone Others
Inaperisone is a novel centrally acting muscle relaxant that inhibits the voiding reflex. Inaperisone may inhibit the voiding reflex by acting indirectly on GABAB receptors in the brainstem.
T38205 3-Aminopropylphosphonic Acid GABA Receptor
3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding assay).
T36520 COR659 Cannabinoid Receptor , GABA Receptor
COR659 is a GABAB positive allosteric modulator (PAM) . COR659 suppresses alcohol and chocolate self-administration in rats[1]. COR659 apparently exerts its effects via a composite mechanism, including positive allosteri...
T8639 Phenibut (hydrochloride) 3-Amino-4-phenylbutyric acid hydrochloride GABA Receptor
Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulates dopamine receptor...
T6355 (R)-baclofen STX209,Arbaclofen GABA Receptor
(R)-baclofen (STX209), a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity.
T2990 Phenibut Phenybut,Fenigam,Fenibut,PhGABA,Aminophenylbutyric acid,β-Phenyl-γ-aminobutyric acid GABA Receptor
Phenibut (Aminophenylbutyric acid) is a central depressant and derivative of the naturally occurring inhibitory neurotransmitter γ-aminobutyric acid (GABA).
T0508 γ-Aminobutyric acid Gamma-aminobutyric acid,4-Aminobutyric acid,GABA,4-Aminobutanoic acid,Piperidic acid GABA Receptor , Endogenous Metabolite
γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system.
T4176 Rac-BHFF (R,S)-BHFF GABA Receptor
rac-BHFF ((R,S)-BHFF) is potent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectively). It exhibits anxiolytic activity in vivo an...
T4881 Phosphorylethanolamine O-Phosphorylethanolamine Others , Endogenous Metabolite
Phosphorylethanolamine (O-Phosphorylethanolamine) is a phosphomonoester metabolite of the phospholipid metabolism. Phosphorylethanolamine is a precursor of phospholipid synthesis and a product of phospholipid breakdown. ...
T15737 Lesogaberan AZD-3355 GABA Receptor
Lesogaberan is an effective and selective GABAB receptor agonist (EC50: 8.6 nM for human recombinant GABAB receptors). For rat brain GABAB and GABAA receptors, the binding affinity (Kis) is 5.1 nM and 1.4 μM, respectivel...
T14938 CGP 36742 SGS-742 GABA Receptor
CGP 36742 is a selective antagonist of the GABAB receptor that can penetrate the blood-brain barrier after peripheral administration (IC50: 32 μM). It is useful in the treatment of depression.
T23368 SKF 97541 Others
GABAB agonist
T28729 SCH-50910 free base SCH50910,SCH 50910
SCH-50910 is an antagonist of GABAB receptor.
T23147 Phaclofen Others
GABAB antagonist
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TargetMol