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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11137 | (E)-GABAB receptor antagonist 1 | GABA Receptor | |
(E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM. GABAB receptor antagonist 1 is ... | |||
T11350 | GABAB receptor antagonist 1 | GABA Receptor | |
(E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM.GABAB receptor antagonist 1 is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric ac... | |||
T21793 | CGP 35348 | GABA Receptor | |
CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after neonatal brain damage in albino mice. | |||
T4363 | CGP52432 | CGP 52432 | GABA Receptor |
CGP52432 is a very potent antagonist of GABAB receptors (IC50 = 85 nM). | |||
T4440 | Saclofen | GABA Receptor | |
Saclofen is a sulfonic analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that acts as a competitive antagonist of the GABAB receptor (IC50: 7.8 μM).1 This compound can be used to determine the function... | |||
T4522 | SSD114 HCl | GABA Receptor | |
SSD114 is a novel GABAB receptor positive allosteric modulator. | |||
T68087 | Inaperisone | Others | |
Inaperisone is a novel centrally acting muscle relaxant that inhibits the voiding reflex. Inaperisone may inhibit the voiding reflex by acting indirectly on GABAB receptors in the brainstem. | |||
T38205 | 3-Aminopropylphosphonic Acid | GABA Receptor | |
3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding assay). | |||
T36520 | COR659 | Cannabinoid Receptor , GABA Receptor | |
COR659 is a GABAB positive allosteric modulator (PAM) . COR659 suppresses alcohol and chocolate self-administration in rats[1]. COR659 apparently exerts its effects via a composite mechanism, including positive allosteri... | |||
T8639 | Phenibut (hydrochloride) | 3-Amino-4-phenylbutyric acid hydrochloride | GABA Receptor |
Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulates dopamine receptor... | |||
T6355 | (R)-baclofen | STX209,Arbaclofen | GABA Receptor |
(R)-baclofen (STX209), a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity. | |||
T2990 | Phenibut | Phenybut,Fenigam,Fenibut,PhGABA,Aminophenylbutyric acid,β-Phenyl-γ-aminobutyric acid | GABA Receptor |
Phenibut (Aminophenylbutyric acid) is a central depressant and derivative of the naturally occurring inhibitory neurotransmitter γ-aminobutyric acid (GABA). | |||
T0508 | γ-Aminobutyric acid | Gamma-aminobutyric acid,4-Aminobutyric acid,GABA,4-Aminobutanoic acid,Piperidic acid | GABA Receptor , Endogenous Metabolite |
γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system. | |||
T4176 | Rac-BHFF | (R,S)-BHFF | GABA Receptor |
rac-BHFF ((R,S)-BHFF) is potent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectively). It exhibits anxiolytic activity in vivo an... | |||
T4881 | Phosphorylethanolamine | O-Phosphorylethanolamine | Others , Endogenous Metabolite |
Phosphorylethanolamine (O-Phosphorylethanolamine) is a phosphomonoester metabolite of the phospholipid metabolism. Phosphorylethanolamine is a precursor of phospholipid synthesis and a product of phospholipid breakdown. ... | |||
T15737 | Lesogaberan | AZD-3355 | GABA Receptor |
Lesogaberan is an effective and selective GABAB receptor agonist (EC50: 8.6 nM for human recombinant GABAB receptors). For rat brain GABAB and GABAA receptors, the binding affinity (Kis) is 5.1 nM and 1.4 μM, respectivel... | |||
T14938 | CGP 36742 | SGS-742 | GABA Receptor |
CGP 36742 is a selective antagonist of the GABAB receptor that can penetrate the blood-brain barrier after peripheral administration (IC50: 32 μM). It is useful in the treatment of depression. | |||
T23368 | SKF 97541 | Others | |
GABAB agonist | |||
T28729 | SCH-50910 free base | SCH50910,SCH 50910 | |
SCH-50910 is an antagonist of GABAB receptor. | |||
T23147 | Phaclofen | Others | |
GABAB antagonist |